Euflammation Attenuates Central and Peripheral Inflammation and Cognitive Consequences of an Immune Challenge after Tumor Development
Conclusion: These results suggest that induction of euflammation may be useful in alleviating the negative side effects of bacterial-based tumor treatments and in potentially attenuating common behavioral comorbidities associated with cancer or other chronic diseases.Neuroimmunomodulation 2017;24:74-86 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - October 25, 2017 Category: Allergy & Immunology Source Type: research
Treatment of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: Follow-Up in 7 Cases
Conclusions: Some patients with GFAP astrocytopathy experienced a poor response to treatment although they received steroids and immunosuppressive agents.Neuroimmunomodulation 2017;24:113-119 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - October 25, 2017 Category: Allergy & Immunology Source Type: research
The Effect of Perceived Stress on Epstein-Barr Virus Antibody Titers in Appalachian Ohio Women
Conclusion: Young Appalachian women reported high levels of perceived stress that were significantly associated with higher EBV titers. Higher perceived social support was associated with lower EBV titers. Health behaviors and Appalachian self-identity did not impact the relationship between perceived stress and EBV titers.Neuroimmunomodulation 2017;24:67-73 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - October 25, 2017 Category: Allergy & Immunology Source Type: research
The Effect of Perceived Stress on Epstein-Barr Virus Antibody Titers in Appalachian Ohio Women
Conclusion: Young Appalachian women reported high levels of perceived stress that were significantly associated with higher EBV titers. Higher perceived social support was associated with lower EBV titers. Health behaviors and Appalachian self-identity did not impact the relationship between perceived stress and EBV titers.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - September 21, 2017 Category: Allergy & Immunology Source Type: research
Treatment of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: Follow-Up in 7 Cases
Conclusions: Some patients with GFAP astrocytopathy experienced a poor response to treatment although they received steroids and immunosuppressive agents.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - September 18, 2017 Category: Allergy & Immunology Source Type: research
Euflammation Attenuates Central and Peripheral Inflammation and Cognitive Consequences of an Immune Challenge after Tumor Development
Conclusion: These results suggest that induction of euflammation may be useful in alleviating the negative side effects of bacterial-based tumor treatments and in potentially attenuating common behavioral comorbidities associated with cancer or other chronic diseases.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - September 12, 2017 Category: Allergy & Immunology Source Type: research
Macrophage-Derived Chemokine: A Putative Marker of Pharmacological Therapy Response in Major Depression?
In this study, we investigated the changes of plasma chemokine levels (eotaxin-1, eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1 α, MIP-1β, and TARC) in 47 MDD patients before (PRE) and after 1 and 6 weeks of pharmacological treatment (POST1 and POST6) in relation to the response to antidepressive therapy. We hypothesized that the direction of alterations in levels of chemokines would significantly differ between the 2 grou ps, responders and nonresponders.Results: Among the investigated chemokines, only the level of macrophage-derived chemokine (MDC) changed significantly in relation to therapy response. MDC levels were sig...
Source: Neuroimmunomodulation - September 12, 2017 Category: Allergy & Immunology Source Type: research
Reply concerning Statistical Comments on “Cytokine and Chemokine Profiles in Patients with Neuromyelitis Optica Spectrum Disorder”
Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 30, 2017 Category: Allergy & Immunology Source Type: research
Statistical Comments on “Cytokine and Chemokine Profiles in Patients with Neuromyelitis Optica Spectrum Disorder”
Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 30, 2017 Category: Allergy & Immunology Source Type: research
Behavioral Conditioning of Immune Responses with Cyclosporine A in a Murine Model of Experimental Autoimmune Uveitis
Conclusions: We conclude that CsA conditioning in the EAU model mitigates Th1 but enhances Th17 immune responses, and does not ameliorate disease. The results imply that in EAU the mechanism of immune conditioning interacts with CFA components during active immunization, most likely via the TLR2/NOD2 pathway, and induces differentiation of Th17 cells that drive autoimmune diseases.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 24, 2017 Category: Allergy & Immunology Source Type: research
Interferon- & #x03B3; Is Associated with Cerebral Atrophy in Systemic Lupus Erythematosus
Objective: We evaluated the cerebrospinal fluid (CSF) cytokine profile and magnetic resonance imaging (MRI) findings in systemic lupus erythematosus (SLE) patients with central nervous system (CNS) involvement.Methods: Consecutive SLE patients followed at the rheumatology unit were enrolled into this study. Neurologically asymptomatic controls were matched for age and sex and recruited during myelography. SLE patients were assessed for disease activity (Systemic Lupus Erythematosus Disease Activity Index; SLEDAI) and cumulative damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology Dama...
Source: Neuroimmunomodulation - August 21, 2017 Category: Allergy & Immunology Source Type: research
GPER Agonist G1 Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson Disease
Conclusion: Our data suggest that GPER mediates the anti-neuroinflammatory effect of estrogen in experimental PD progression.Neuroimmunomodulation 2017;24:60-66 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 15, 2017 Category: Allergy & Immunology Source Type: research
The Effects of Adenosinergic Modulation on Cytokine Levels in a Pentylenetetrazole-Induced Generalized Tonic-Clonic Seizure Model
Conclusion: Our results show that there is a clear relation between adenosinergic system and brain tissue cytokine levels. Our findings indicated that TNF- α, IL-1β, and IL-6 participate in the pathogenesis of generalized seizures, and the inhibition of TNF-α, IL-1β, and IL-6 with adenosinergic modulation may decrease seizure severity.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 9, 2017 Category: Allergy & Immunology Source Type: research
Beta-Adrenergic Blockade Decreases the Neuroimmune Changes in Mice Induced by Cohabitation with an Ehrlich Tumor-Bearing Cage Mate
Conclusion: These results confirm and strengthen our hypothesis that the SNS is involved in the effects induced by cohabitation with ETB mice and point towards β2-AR participation in the immune effects analyzed.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 8, 2017 Category: Allergy & Immunology Source Type: research
Deletion of the Inflammasome Sensor Aim2 Mitigates A β Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model
Conclusion: AlthoughAim2 knockout mitigates A β deposition and microglial activation,Aim2 deletion does not have a beneficial effect on the spatial memory or cytokine expression of 5XFAD mice. Our findings suggest that A β aggregation and microglial activation may not always be correlated with the expression of inflammatory cytokines or cognitive function of 5XFAD mice. Our study also implies that different inflammasomes likely perform distinct roles in different physiological and/or pathological events.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - June 16, 2017 Category: Allergy & Immunology Source Type: research
