Neuroprotective Effect of HOTAIR Silencing on Isoflurane-Induced Cognitive Dysfunction via Sponging microRNA-129-5p and Inhibiting Neuroinflammation
Conclusion: Lowly expressed HOTAIR contributed to the recovery of the ISO-injured HT22 cell model from the abnormal viability, apoptosis, inflammation, and oxidative stress by regulating miR-129-5p. miR-129-5p mediated the function of HOTAIR on cognition and oxidative balance in the ISO-managed SD rat model.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - January 13, 2022 Category: Allergy & Immunology Source Type: research
New Editor-in-Chief ’s Note: The Past and the Future
Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - January 3, 2022 Category: Allergy & Immunology Source Type: research
Berberine Protects against Neurological Impairments and Blood-Brain Barrier Injury in Mouse Model of Intracerebral Hemorrhage
Conclusion: Our findings suggest that Berberine plays an important neuroprotective role against ICH-induced neurological impairments and BBB injury, probably by inhibition of inflammation and activation of AMPK/PGC1 α signaling.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - December 23, 2021 Category: Allergy & Immunology Source Type: research
Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist
Conclusion: ZAPL and ZAPS were expressed in hCMEC/D3 cells, and ZAPS expression was upregulated by poly IC. IRF3 and TRIM25 are involved in poly IC-induced upregulation of ZAPS. ZAP may contribute to antiviral reactions in brain microvascular endothelial cells and protect the brain from invading viruses such as JEV.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - December 22, 2021 Category: Allergy & Immunology Source Type: research
Lymphocyte Subsets Are Associated with Disease Status in Neuromyelitis Optica Spectrum Disorders
Conclusions: The levels of certain subsets of peripheral blood lymphocytes are associated with disease status in NMOSD.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - December 14, 2021 Category: Allergy & Immunology Source Type: research
The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195
Conclusion: Picroside II could protect the nervous system possibly through inhibiting the inflammatory response in the isoflurane-induced neuronal injury of rats. The protective effect of picroside II may be achieved by downregulating the expression of miR-195 and then inhibiting the inflammatory response.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - December 9, 2021 Category: Allergy & Immunology Source Type: research
Effects of Long Noncoding RNA H19 on Isoflurane-Induced Cognitive Dysregulation by Promoting Neuroinflammation
Conclusion: Our results of in vitro and in vivo assay indicated that the absence of HT22 is a neuroprotective regulator of cognition and inflammation by accumulating miR-17-5p.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - December 2, 2021 Category: Allergy & Immunology Source Type: research
Clinical Heterogeneity in Acute Symptomatic Seizures due to Autoimmune Encephalitis Related to GAD65 Antibodies
Conclusions: Clinical features of acute symptomatic seizures related to GAD65 antibodies are diverse, and early and continuous immunotherapy is necessary for patients.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 30, 2021 Category: Allergy & Immunology Source Type: research
Distinct Immunological Features of Inflammatory Demyelinating Diseases of the Central Nervous System
Conclusions: NMOSD, MS, and MOGAD may be different in pathogenesis, and several immunological biomarkers can serve as potential classifiers clinically.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 25, 2021 Category: Allergy & Immunology Source Type: research
The Effect of Interferon-Beta Therapy on T-Helper 17/miR-326 and T-Helper 1/miR-29b-3p Axis in Relapsing-Remitting Multiple Sclerosis Patients
Conclusion: IFN- β therapy is more effective on Th17 than Th1, but it does not reform altered expression of hsa-miR-326 and hsa-miR-29b-3p in Th17 and Th1, respectively.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 22, 2021 Category: Allergy & Immunology Source Type: research
Differential Expression of miR-381-3p in Alzheimer ’s Disease Patients and Its Role in Beta-Amyloid-Induced Neurotoxicity and Inflammation
Conclusion: miR-381-3p is less expressed in the serum of AD patients and has potential diagnostic values for AD. Overexpression of miR-381-3p may attenuate A β25-35-induced neurotoxicity and inflammatory responses via targeting PTGS2 in SH-SY5Y cells.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 8, 2021 Category: Allergy & Immunology Source Type: research
Zuogui Pill Attenuates Neuroinflammation and Improves Cognitive Function in Cerebral Ischemia Reperfusion-Injured Rats
Conclusion: This study provided protective roles of ZGP on cell viability and apoptosis induced by OGD/R. In addition, ZGP played protective roles on neuroinflammation and cognitive function in rats.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 4, 2021 Category: Allergy & Immunology Source Type: research
Contents Vol. 28, 2021
Neuroimmunomodulation 2021;28:I –IV (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 2, 2021 Category: Allergy & Immunology Source Type: research
Acknowledgement to Reviewers
Neuroimmunomodulation 2021;28:276 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - November 2, 2021 Category: Allergy & Immunology Source Type: research
Association between Serum Prolactin Levels and Neurodegenerative Diseases: Systematic Review and Meta-Analysis
Conclusions: Our meta-analysis showed serum PRL levels in patients with HD and MS were significantly higher than those in healthy controls. Serum PRL levels were associated with age, region, and detection method. Other larger sample studies using more uniform detection methods are necessary to confirm our results.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - October 20, 2021 Category: Allergy & Immunology Source Type: research
