Exaggerated Increases in Microglia Proliferation, Brain Inflammatory Response and Sickness Behaviour upon Lipopolysaccharide Stimulation in Non-Obese Diabetic Mice
Conclusion: After stimulation with LPS, NOD mice display an increased microglial proliferation and an exaggerated inflammatory brain response with reduced BDNF and PDGF expression and increased sickness behaviour as compared to controls.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - August 16, 2016 Category: Allergy & Immunology Source Type: research
1,25-Dihydroxyvitamin D < sub > 3 < /sub > Facilitates M2 Polarization and Upregulates TLR10 Expression on Human Microglial Cells
Conclusions: < /i > < /b > Our results suggest that 1,25(OH) < sub > 2 < /sub > D < sub > 3 < /sub > may exert anti-inflammatory action by facilitating the M2 polarization of human microglial cells. < br / > Neuroimmunomodulation 2016;23:75-80 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - July 21, 2016 Category: Allergy & Immunology Source Type: research
The Possible Role of Toll-Like Receptor 4 in the Pathology of Stroke
This article reviews recent information regarding the impact of TLR4 on the pathogenicity of stroke.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - June 8, 2016 Category: Allergy & Immunology Source Type: research
Effects of Hyperbaric Oxygen Therapy on Inflammasome Signaling after Traumatic Brain Injury
Conclusion: These results suggest that HBOT may alleviate the inflammatory response after TBI by inhibiting the activation of inflammasome signaling.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 24, 2016 Category: Allergy & Immunology Source Type: research
A Helminth Protease Inhibitor Modulates the Lipopolysaccharide-Induced Proinflammatory Phenotype of Microglia in vitro
Conclusion: The parasite-derived secretion product Av-cystatin inhibits proinflammatory mechanisms of LPS-induced microglia with IL-10, a potential key mediator.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - April 18, 2016 Category: Allergy & Immunology Source Type: research
