Diversifying editorial boards to mitigate the global burden of genitourinary cancers
Nature Reviews Urology, Published online: 01 March 2024; doi:10.1038/s41585-024-00867-xThe growing global burden of genitourinary cancers is disproportionately shouldered by low- and middle-income countries. Medical journals offer an avenue for discourse among different stakeholders to strategize and identify solutions. Thus, achieving diversity in this context is crucial to put together a heterogeneous group of stakeholders with diverse personal and cultural experiences as well as distinct problem-solving approaches. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 1, 2024 Category: Urology & Nephrology Authors: David J. Benjamin Zhaohui Arter Nataliya Mar Arash Rezazadeh Kalebasty Source Type: research
Targeting histone modifiers in bladder cancer therapy — preclinical and clinical evidence
Nature Reviews Urology, Published online: 19 February 2024; doi:10.1038/s41585-024-00857-zIn this Perspective, the authors discuss the idea of targeting histone modifications in bladder cancer, providing a comprehensive overview of findings from preclinical and translational studies. Clinical trials in which the efficacy of molecules targeting histone modifiers was assessed in bladder cancer are also discussed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 19, 2024 Category: Urology & Nephrology Authors: Shiyu Zhang Tianhai Lin Xingyu Xiong Chong Chen Ping Tan Qiang Wei Source Type: research
The evolving management of small renal masses
Nature Reviews Urology, Published online: 16 February 2024; doi:10.1038/s41585-023-00848-6The evaluation and management of patients with small renal masses continue to evolve as new data-driven evidence emerges. Contemporary research in biomarkers, imaging, and machine learning shows promise in improving the understanding of small renal masses. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2024 Category: Urology & Nephrology Authors: Yuzhi Wang Mohit Butaney Samantha Wilder Khurshid Ghani Craig G. Rogers Brian R. Lane Source Type: research
Sun, sea, sex and spaghetti as the ESSM hits Bari
Nature Reviews Urology, Published online: 16 February 2024; doi:10.1038/s41585-024-00864-0Sun, sea, sex and spaghetti as the ESSM hits Bari (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2024 Category: Urology & Nephrology Authors: Annette Fenner Source Type: research
First-morning urine samples to study the urobiome
Nature Reviews Urology, Published online: 14 February 2024; doi:10.1038/s41585-024-00861-3First-morning urine samples to study the urobiome (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 14, 2024 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
A new rapid point-of-care test for N. gonorrhoeae
Nature Reviews Urology, Published online: 14 February 2024; doi:10.1038/s41585-024-00860-4A new rapid point-of-care test for N. gonorrhoeae (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 14, 2024 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
ADT intensification to treat biochemically recurrent prostate cancer
Nature Reviews Urology, Published online: 14 February 2024; doi:10.1038/s41585-024-00862-2ADT intensification to treat biochemically recurrent prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 14, 2024 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Mellow yellow: BilR reduces bilirubin to urobilinogen
Nature Reviews Urology, Published online: 14 February 2024; doi:10.1038/s41585-024-00863-1Mellow yellow: BilR reduces bilirubin to urobilinogen (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 14, 2024 Category: Urology & Nephrology Authors: Louise Lloyd Source Type: research
RNA N6-methyladenosine modifications in urological cancers: from mechanism to application
Nature Reviews Urology, Published online: 12 February 2024; doi:10.1038/s41585-023-00851-xRNA m6A modifications have emerged as an important contributor to urological cancer biology. Yang et al. highlight the multifarious roles of m6A modifications and discuss the knowledge gap between molecular understanding and clinical applications. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 12, 2024 Category: Urology & Nephrology Authors: Lei Yang Jianming Ying Qian Tao Qian Zhang Source Type: research
Mechanisms of oxidative stress in interstitial cystitis/bladder pain syndrome
Nature Reviews Urology, Published online: 07 February 2024; doi:10.1038/s41585-023-00850-yOxidative stress and reactive oxygen species contribute to the pathophysiology of interstitial cystitis/bladder pain syndrome through their effects on molecular pathways. Here, the authors discuss these pathways, animal models of interstitial cystitis/bladder pain syndrome and treatment options for the disease. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2024 Category: Urology & Nephrology Authors: Ashu Mohammad Mallory A. Laboulaye Chen Shenhar Amy D. Dobberfuhl Source Type: research
Molecular profile of bladder cancer progression to clinically aggressive subtypes
Nature Reviews Urology, Published online: 06 February 2024; doi:10.1038/s41585-023-00847-7In this Review, the authors describe the molecular profile of bladder cancer progression associated with the subtypes of this disease and comment on their potential diagnostic, prognostic and therapeutic importance. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 6, 2024 Category: Urology & Nephrology Authors: Charles C. Guo Sangkyou Lee June G. Lee Huiqin Chen Michael Zaleski Woonyoung Choi David J. McConkey Peng Wei Bogdan Czerniak Source Type: research
Supplementary selenium and vitamin E in non-muscle-invasive bladder cancer
Nature Reviews Urology, Published online: 05 February 2024; doi:10.1038/s41585-024-00859-xIn the SELENIB trial, selenium and vitamin E were compared with placebo as chemoprevention for non-muscle-invasive bladder cancer (NMIBC). No difference versus placebo was observed in recurrence-free interval (RFI) with selenium, but vitamin E was associated with worse RFI. Selenium and vitamin E cannot be recommended in chemoprevention for NMIBC. Furthermore, patients with NMIBC taking supplemental vitamin E should be made aware of its potential association with worse RFI. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 5, 2024 Category: Urology & Nephrology Authors: Shaun J. Trecarten Robert S. Svatek Source Type: research
The complex interplay of modifiable risk factors affecting prostate cancer disparities in African American men
Nature Reviews Urology, Published online: 02 February 2024; doi:10.1038/s41585-023-00849-5African American men are disproportionately affected by prostate cancer in the USA. In this Review, the authors discuss the complex interplay of modifiable risk factors that might underlie the glaring prostate cancer disparities observed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 2, 2024 Category: Urology & Nephrology Authors: Jabril R. Johnson Nicole Mavingire Leanne Woods-Burnham Mya Walker Deyana Lewis Stanley E. Hooker Dorothy Galloway Brian Rivers Rick A. Kittles Source Type: research
The yin and yang of chromosomal instability in prostate cancer
Nature Reviews Urology, Published online: 02 February 2024; doi:10.1038/s41585-023-00845-9Chromosomal instability is a hallmark of advanced prostate cancer. In this Review, the authors discuss the biological causes and paradoxical consequences of chromosomal instability, its potential clinical role in the stratification of prostate cancer aggressiveness and the development of novel treatment strategies. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 2, 2024 Category: Urology & Nephrology Authors: Marc Carceles-Cordon Jacob J. Orme Josep Domingo-Domenech Veronica Rodriguez-Bravo Source Type: research
Management of patients with muscle-invasive bladder cancer with clinical evidence of pelvic lymph node metastases
Nature Reviews Urology, Published online: 31 January 2024; doi:10.1038/s41585-023-00842-yMuscle-invasive bladder cancer with clinically positive pelvic lymph nodes is a particular situation at the interface between localized and metastatic disease. In this Review, the authors discuss the advances and challenges of currently available strategies for the diagnosis and treatment of patients with muscle-invasive bladder cancer with clinically positive pelvic lymph nodes. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 31, 2024 Category: Urology & Nephrology Authors: Elisabeth Grobet-Jeandin Louis Lenfant Ugo Pinar J érôme Parra Pierre Mozer Raphaele Renard-Penna Constance Thibault Morgan Roupr êt Thomas Seisen Source Type: research
