Recurrence mechanisms of non-muscle-invasive bladder cancer — a clinical perspective
Nature Reviews Urology, Published online: 31 March 2022; doi:10.1038/s41585-022-00578-1In this Review, Teoh et al. describe different mechanisms of early and late disease recurrence in non-muscle-invasive bladder cancer and discuss potential treatment options. In addition, the authors discuss the potential of molecular classification and treatment with immunotherapy and novel therapeutic agents in the future management of bladder cancer. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 31, 2022 Category: Urology & Nephrology Authors: Jeremy Yuen-Chun Teoh Ashish M. Kamat Peter C. Black Petros Grivas Shahrokh F. Shariat Marek Babjuk Source Type: research

Is SARS-CoV-2-induced testicular damage in hamsters relevant?
Nature Reviews Urology, Published online: 31 March 2022; doi:10.1038/s41585-022-00589-yThe extent, duration and causes of alterations in the testes caused by SARS-CoV-2 are unclear. A new study has documented the effects of SARS-CoV-2 infection on the testes of a golden Syrian hamster model; however, the relevance of these findings to non-severe human infection is questionable. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 31, 2022 Category: Urology & Nephrology Authors: Nathalie Dejucq-Rainsford Source Type: research

Microbiota manipulation to prevent oxalate kidney stone formation
Nature Reviews Urology, Published online: 16 March 2022; doi:10.1038/s41585-022-00585-2Microbiota manipulation to prevent oxalate kidney stone formation (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 16, 2022 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

AI for prostate cancer diagnosis — hype or today’s reality?
Nature Reviews Urology, Published online: 11 March 2022; doi:10.1038/s41585-022-00583-4Artificial intelligence (AI)-based models can potentially reduce workload and assist general pathologists in reaching genitourinary pathologists’ performance. A recent large-scale competition to develop generalizable AI models for prostate cancer detection and grading has shown success; implementation of such models positions them beyond hype and as today’s reality. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 11, 2022 Category: Urology & Nephrology Authors: Ali Bashashati S. Larry Goldenberg Source Type: research

Sexual recovery interventions following prostate cancer treatment
Nature Reviews Urology, Published online: 11 March 2022; doi:10.1038/s41585-022-00582-5Sexual adverse effects from prostate cancer treatment are a substantial burden for patients. An online biopsychosocial sexual rehabilitation intervention for patients with prostate cancer (TrueNTH) was implemented in several cancer centres in the USA. Outcomes from this intervention show no improvements in sexual satisfaction after 6 months; however, earlier resumption of sexual activities was observed 3 months after the intervention. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 11, 2022 Category: Urology & Nephrology Authors: Lauren M. Walker Source Type: research