The future of patient-derived xenografts in prostate cancer research
Nature Reviews Urology, Published online: 17 January 2023; doi:10.1038/s41585-022-00706-xThis Perspective covers existing patient-derived xenografts (PDXs) of prostate cancer, and their features and uses in basic and preclinical research. The authors also discuss the need for additional PDXs, and how collaboration in prostate cancer PDX research can be improved. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 17, 2023 Category: Urology & Nephrology Authors: Mitchell G. Lawrence Renea A. Taylor Georgia B. Cuffe Lisa S. Ang Ashlee K. Clark David L. Goode Laura H. Porter Cl émentine Le Magnen Nora M. Navone Jack A. Schalken Yuzhuo Wang Wytske M. van Weerden Eva Corey John T. Isaacs Peter S. Nelson Gail P. Risb Source Type: research

Can systematic biopsy be omitted from the prostate cancer diagnostic pathway?
Nature Reviews Urology, Published online: 11 January 2023; doi:10.1038/s41585-023-00724-3Can systematic biopsy be omitted from the prostate cancer diagnostic pathway? (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 11, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria
Nature Reviews Urology, Published online: 10 January 2023; doi:10.1038/s41585-022-00699-7In this Review, Lopez et al. discuss the history of penile transplantation, including the procedures and outcomes of transplants to date, as well as factors to consider for consistent, optimal outcomes. The authors also discuss the future of penile transplantation and suggest updates to the Baltimore criteria. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 10, 2023 Category: Urology & Nephrology Authors: Christopher D. Lopez Alisa O. Girard Isabel V. Lake Byoung Chol Oh Gerald Brandacher Damon S. Cooney Arthur L. Burnett Richard J. Redett Source Type: research

VR, reconstructive urology and the future of surgery education
Nature Reviews Urology, Published online: 05 January 2023; doi:10.1038/s41585-022-00722-xThe COVID-19 pandemic has disrupted surgical training worldwide, and reconstructive urology training has been neglected at the expense of more urgent life-saving procedures. To help address this problem, virtual reality must become a fundamental training aid in modern reconstructive urology surgery education. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 5, 2023 Category: Urology & Nephrology Authors: Miko łaj Frankiewicz Malte W. Vetterlein Marcin Matuszewski Source Type: research

Modelling AR mutations
Nature Reviews Urology, Published online: 05 January 2023; doi:10.1038/s41585-022-00718-7Modelling AR mutations (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 5, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Cribriform morphology affects mpMRI imaging
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00719-6Cribriform morphology affects mpMRI imaging (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Molecular characterization of tRCC
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00714-xMolecular characterization of tRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

ARBS heterogeneity in prostate cancer progression
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00716-9ARBS heterogeneity in prostate cancer progression (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Transcription factors in kidney stone disease
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00720-zTranscription factors in kidney stone disease (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

A CAF subcluster regulates bladder cancer stemness
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00713-yA CAF subcluster regulates bladder cancer stemness (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Irreversible electroporation in radio-recurrent prostate cancer
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00715-wIrreversible electroporation in radio-recurrent prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Linking the CNS and bladder dysfunction
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00721-yLinking the CNS and bladder dysfunction (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00680-4Mutations in the BRCA1 and BRCA2 tumour suppressor genes are associated with prostate cancer risk, but optimal screening protocols for individuals with these mutations have been a subject of debate. In this Review, the authors discuss the risk associated with BRCA1/2 mutations and consider how, and whether, a screening programme should be implemented for these individuals. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Pawel Rajwa Fahad Quhal Benjamin Pradere Giorgio Gandaglia Guillaume Ploussard Michael S. Leapman John L. Gore Andrzej Paradysz Derya Tilki Axel S. Merseburger Todd M. Morgan Alberto Briganti Ganesh S. Palapattu Shahrokh F. Shariat Source Type: research

A vagina on a chip to model microbiome–host interactions
Nature Reviews Urology, Published online: 04 January 2023; doi:10.1038/s41585-022-00717-8A vagina on a chip to model microbiome–host interactions (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 4, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Author Correction: Can PROMs improve racial equity in outcomes after prostatectomy?
Nature Reviews Urology, Published online: 22 December 2022; doi:10.1038/s41585-022-00712-zAuthor Correction: Can PROMs improve racial equity in outcomes after prostatectomy? (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 22, 2022 Category: Urology & Nephrology Authors: Alexander P. Cole Mara Koelker Jonathan Makanjuola Caroline M. Moore Source Type: research