Metabolic flexibility in ccRCC
Nature Reviews Urology, Published online: 10 February 2023; doi:10.1038/s41585-023-00734-1Metabolic flexibility in ccRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 10, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Human in vitro spermatogenesis as a regenerative therapy — where do we stand?
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00723-4Several approaches have been used to date to reproduce human spermatogenesis in vitro, which, however, mostly result in incomplete differentiation. In this Review, the authors describe advantages and limitations of current technologies for in vitro spermatogenesis. New approaches that could lead to the clinical translation of this technology to treat patients with male factor infertility are also discussed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Meghan Robinson Sydney Sparanese Luke Witherspoon Ryan Flannigan Source Type: research

Prostate cancer care for American Indians and Alaska Natives
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00731-4Prostate cancer care for American Indians and Alaska Natives (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

CMA mediates resistance to androgen inhibitors in prostate cancer
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00729-yCMA mediates resistance to androgen inhibitors in prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Calculating the environmental cost of care
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00733-2Calculating the environmental cost of care (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

A new text message-based platform for self-management of patients with IC/BPS
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00730-5A new text message-based platform for self-management of patients with IC/BPS (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

GAH treatment improves mental health in transgender adolescents
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00728-zGAH treatment improves mental health in transgender adolescents (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Principles and outcomes of gender-affirming vaginoplasty
Nature Reviews Urology, Published online: 01 February 2023; doi:10.1038/s41585-022-00705-yIn this Review, the authors describe the evolution of vaginoplasty including surgical techniques, complications, and clinical and patient-reported outcomes and consider current controversies in techniques and areas for improvement. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 1, 2023 Category: Urology & Nephrology Authors: Shane D. Morrison Karel Claes Martin P. Morris Stan Monstrey Piet Hoebeke Marlon Buncamper Source Type: research

Inheritance of paternal lifestyles and exposures through sperm DNA methylation
Nature Reviews Urology, Published online: 18 January 2023; doi:10.1038/s41585-022-00708-9Here, the authors explore how environmentally driven changes in the sperm epigenome can mediate paternal contributions to offspring health. They also describe innovations in human stem cell models that can be used to elucidate the paternal origins of health and disease. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 18, 2023 Category: Urology & Nephrology Authors: Katherine W. Greeson Krista M. S. Crow R. Clayton Edenfield Charles A. Easley IV Source Type: research

Landmarks in the evolution of prostate biopsy
Nature Reviews Urology, Published online: 18 January 2023; doi:10.1038/s41585-022-00684-0Since its inception in 1922, prostate biopsy has undergone considerable changes in both technique and indication. In this Perspective, the authors describe the history of prostate biopsy and consider the role of imaging in prostate biopsy, now and in the future. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 18, 2023 Category: Urology & Nephrology Authors: Martin J. Connor Michael A. Gorin David Eldred-Evans Edward J. Bass Ankit Desai Tim Dudderidge Mathias Winkler Hashim U. Ahmed Source Type: research

Health-related quality of life after curative treatment for muscle-invasive bladder cancer
Nature Reviews Urology, Published online: 18 January 2023; doi:10.1038/s41585-022-00693-zHealth-related quality of life can be affected by muscle-invasive bladder cancer treatment and should be assessed all the way through patient’s care. In this Review, the authors summarize available data on patient health-related quality of life after curative local treatment for muscle-invasive bladder cancer, also considering the effect of different surgical procedures or urinary diversion methods on patient quality of life. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 18, 2023 Category: Urology & Nephrology Authors: Elisabeth Grobet-Jeandin Ugo Pinar J érôme Parra Morgan Roupr êt Thomas Seisen Source Type: research

The future of patient-derived xenografts in prostate cancer research
Nature Reviews Urology, Published online: 17 January 2023; doi:10.1038/s41585-022-00706-xThis Perspective covers existing patient-derived xenografts (PDXs) of prostate cancer, and their features and uses in basic and preclinical research. The authors also discuss the need for additional PDXs, and how collaboration in prostate cancer PDX research can be improved. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 17, 2023 Category: Urology & Nephrology Authors: Mitchell G. Lawrence Renea A. Taylor Georgia B. Cuffe Lisa S. Ang Ashlee K. Clark David L. Goode Laura H. Porter Cl émentine Le Magnen Nora M. Navone Jack A. Schalken Yuzhuo Wang Wytske M. van Weerden Eva Corey John T. Isaacs Peter S. Nelson Gail P. Risb Source Type: research

Can systematic biopsy be omitted from the prostate cancer diagnostic pathway?
Nature Reviews Urology, Published online: 11 January 2023; doi:10.1038/s41585-023-00724-3Can systematic biopsy be omitted from the prostate cancer diagnostic pathway? (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 11, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria
Nature Reviews Urology, Published online: 10 January 2023; doi:10.1038/s41585-022-00699-7In this Review, Lopez et al. discuss the history of penile transplantation, including the procedures and outcomes of transplants to date, as well as factors to consider for consistent, optimal outcomes. The authors also discuss the future of penile transplantation and suggest updates to the Baltimore criteria. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 10, 2023 Category: Urology & Nephrology Authors: Christopher D. Lopez Alisa O. Girard Isabel V. Lake Byoung Chol Oh Gerald Brandacher Damon S. Cooney Arthur L. Burnett Richard J. Redett Source Type: research

VR, reconstructive urology and the future of surgery education
Nature Reviews Urology, Published online: 05 January 2023; doi:10.1038/s41585-022-00722-xThe COVID-19 pandemic has disrupted surgical training worldwide, and reconstructive urology training has been neglected at the expense of more urgent life-saving procedures. To help address this problem, virtual reality must become a fundamental training aid in modern reconstructive urology surgery education. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 5, 2023 Category: Urology & Nephrology Authors: Miko łaj Frankiewicz Malte W. Vetterlein Marcin Matuszewski Source Type: research