The prostatic middle lobe: clinical significance, presentation and management
Nature Reviews Urology, Published online: 15 May 2023; doi:10.1038/s41585-023-00774-7In this Review, the authors examine the prevalence of middle lobe enlargement in benign prostatic hyperplasia (BPH). The clinical significance, presentation, pathophysiology and assessment of middle lobe obstruction is discussed. The spectrum of management options in BPH is reviewed and their applicability in middle lobe enlargement debated. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 15, 2023 Category: Urology & Nephrology Authors: Sammy Gharbieh Fairleigh Reeves Ben Challacombe Source Type: research
AUA returns to its former glory in Chicago
Nature Reviews Urology, Published online: 12 May 2023; doi:10.1038/s41585-023-00779-2AUA returns to its former glory in Chicago (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 12, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Vitamins as regulators of calcium-containing kidney stones — new perspectives on the role of the gut microbiome
Nature Reviews Urology, Published online: 09 May 2023; doi:10.1038/s41585-023-00768-5In this Perspective article, the authors summarize the roles of vitamins in calcium-containing kidney stone disease, and hypothesize implications for the gut microbiota in altering vitamin homeostasis by modulating vitamin absorption, production and chemical modification. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 9, 2023 Category: Urology & Nephrology Authors: John A. Chmiel Gerrit A. Stuivenberg Kait F. Al Polycronis P. Akouris Hassan Razvi Jeremy P. Burton Jennifer Bjazevic Source Type: research
Women in urology — closing the gap
Nature Reviews Urology, Published online: 28 April 2023; doi:10.1038/s41585-023-00777-4Urology is a historically male-dominated field and, although the number of women is increasing, gender equity is still far off. All members of the urology community need to work together to drive a change. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 28, 2023 Category: Urology & Nephrology Source Type: research
PROTACs for prostate cancer
Nature Reviews Urology, Published online: 21 April 2023; doi:10.1038/s41585-023-00772-9PROTACs for prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 21, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research
Working harder for less — under-represented in medicine women in academic and clinical urology
Nature Reviews Urology, Published online: 20 April 2023; doi:10.1038/s41585-023-00767-6The gender gap among urologists is narrowing, but representation of women from under-represented in medicine (URiM) groups remains low. URiM women face the added challenge of contending with tokenism. Intentional sponsorship and coaching, as well as institutional efforts to establish an inclusive and equitable workplace culture, are imperative to abolish the lag in promotion and academic achievement of these women. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 20, 2023 Category: Urology & Nephrology Authors: Efe Chantal Ghanney Simons Oluwarotimi S. Nettey Source Type: research
The androgen receptor in bladder cancer
Nature Reviews Urology, Published online: 18 April 2023; doi:10.1038/s41585-023-00761-yIn this Review, the authors summarize the roles of the androgen receptor in bladder cancer development and progression, and describe the clinical applications of these roles. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 18, 2023 Category: Urology & Nephrology Authors: Jinbo Chen Chi-Ping Huang Chao Quan Xiongbing Zu Zhenyu Ou Yu-Chieh Tsai Edward Messing Shuyuan Yeh Chawnshang Chang Source Type: research
Going in circles: circMGA–HNRNPL feedback loop in bladder cancer
Nature Reviews Urology, Published online: 17 April 2023; doi:10.1038/s41585-023-00771-wGoing in circles: circMGA–HNRNPL feedback loop in bladder cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 17, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research
Using AI to assist pathologists in bladder cancer metastases detection
Nature Reviews Urology, Published online: 14 April 2023; doi:10.1038/s41585-023-00769-4Using AI to assist pathologists in bladder cancer metastases detection (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 14, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Embryonal origin of adult testicular macrophages
Nature Reviews Urology, Published online: 14 April 2023; doi:10.1038/s41585-023-00770-xEmbryonal origin of adult testicular macrophages (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 14, 2023 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
A sparkling golden anniversary EAU23 Congress sees batons passed in Milan
Nature Reviews Urology, Published online: 11 April 2023; doi:10.1038/s41585-023-00766-7A sparkling golden anniversary EAU23 Congress sees batons passed in Milan (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 11, 2023 Category: Urology & Nephrology Authors: Annette Fenner Source Type: research
Genetic control of typical and atypical sex development
Nature Reviews Urology, Published online: 05 April 2023; doi:10.1038/s41585-023-00754-xIn this Review, Reyes et al. provide an overview of the embryology and genetics of typical sex development, before discussing the clinical manifestations, genetic causes and phenotypic complexity of differences in sex development. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 5, 2023 Category: Urology & Nephrology Authors: Alejandra P. Reyes Nayla Y. Le ón Emily R. Frost Vincent R. Harley Source Type: research
Unanswered questions in prostate cancer — findings of an international multi-stakeholder consensus by the PIONEER consortium
Nature Reviews Urology, Published online: 03 April 2023; doi:10.1038/s41585-023-00748-9In this Consensus Statement, the authors present results from an international multi-stakeholder consensus conducted by the PIONEER consortium to identify the most important questions in the field of prostate cancer that could be addressed using big data. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 3, 2023 Category: Urology & Nephrology Authors: Muhammad Imran Omar Steven MacLennan Maria J. Ribal Monique J. Roobol Konstantinos Dimitropoulos Thomas van den Broeck Sara J. MacLennan Susan Evans Axelsson Giorgio Gandaglia Peter-Paul Willemse Ken Mastris John Butler Ransohoff Zsuzsanna Devecseri Thoma Source Type: research
Patient preferences in the treatment of genitourinary cancers
Nature Reviews Urology, Published online: 03 April 2023; doi:10.1038/s41585-023-00765-8Several newly approved therapies have substantially altered the treatment paradigm for multiple genitourinary cancers. Considering the existence of numerous possible treatment approaches, understanding which treatment attributes are most valued by each patient is crucial to physicians to recommend a cancer-directed treatment. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 3, 2023 Category: Urology & Nephrology Authors: David J. Benjamin Arash Rezazadeh Kalebasty Source Type: research
Circulating and urinary tumour DNA in urothelial carcinoma — upper tract, lower tract and metastatic disease
Nature Reviews Urology, Published online: 28 March 2023; doi:10.1038/s41585-023-00725-2Non-invasive liquid biopsies such as plasma circulating tumour DNA (ctDNA) and urinary tumour DNA (utDNA) are promising tools for urothelial carcinoma diagnosis and management. In this Review, the authors provide an overview of the different liquid biopsy technologies available, and discuss the current state as well as future perspectives of ctDNA and utDNA application in urothelial carcinoma clinical care. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 28, 2023 Category: Urology & Nephrology Authors: Kyle M. Rose Heather L. Huelster Joshua J. Meeks Bishoy M. Faltas Guru P. Sonpavde Seth P. Lerner Jeffrey S. Ross Philippe E. Spiess G. Daniel Grass Rohit K. Jain Ashish M. Kamat Aram Vosoughi Liang Wang Xuefeng Wang Roger Li Source Type: research
