Local anaesthetic techniques for performing transperineal prostate biopsy
Nature Reviews Urology, Published online: 01 March 2021; doi:10.1038/s41585-021-00443-7New technical modifications enable transperineal prostate biopsy to be performed in the ambulatory setting under local anaesthesia. Although a variety of techniques for administration of local anaesthetic during transperineal prostate biopsy have been described, no consensus exists regarding the most effective method to use. Thus, ample opportunity exists for procedural innovation and future study on this topic. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 1, 2021 Category: Urology & Nephrology Authors: Spyridon P. Basourakos Mathew J. Allaway Ashley E. Ross Edward M. Schaeffer Jim C. Hu Michael A. Gorin Source Type: research

Considering the potential for gene-based therapy in prostate cancer
Nature Reviews Urology, Published online: 26 February 2021; doi:10.1038/s41585-021-00431-xProstate cancer lends itself to gene therapies, and multiple aspects of prostate cancer care make gene therapy an appealing treatment option for this common malignancy. Although laboratory and preclinical advances have not yet resulted in oncologically relevant outcomes in the clinic, future studies offer great promise for gene therapy to become established in prostate cancer treatment. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 26, 2021 Category: Urology & Nephrology Authors: Justin R. Gregg Timothy C. Thompson Source Type: research

Attention to detail and a permissive set-up: crucial for an effective TURBT
Nature Reviews Urology, Published online: 24 February 2021; doi:10.1038/s41585-021-00441-9An effective transurethral resection of bladder tumour (TURBT) is essential to achieve safe tumour clearance and to determine the biological potential of the cancer. Attention to surgical detail within a set-up that embraces evidence-based practice, training, quality standards, prospective audit and feedback will facilitate these objectives. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 24, 2021 Category: Urology & Nephrology Authors: Paramananthan Mariappan Source Type: research

Advances in the selection of patients with prostate cancer for active surveillance
Nature Reviews Urology, Published online: 23 February 2021; doi:10.1038/s41585-021-00432-wAccurate selection of patients with low-risk prostate cancer for active surveillance relies upon conventional clinical staging and grading criteria. New approaches in imaging as well as novel serum-, urine- and tissue-based biomarkers have been developed to reduce initial misclassification and predict risk of disease progression. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 23, 2021 Category: Urology & Nephrology Authors: James L. Liu Hiten D. Patel Nora M. Haney Jonathan I. Epstein Alan W. Partin Source Type: research

An ACE2 in the kidney
Nature Reviews Urology, Published online: 16 February 2021; doi:10.1038/s41585-021-00439-3An ACE2 in the kidney (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2021 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Radiotheranostic targeting of fPSA
Nature Reviews Urology, Published online: 09 February 2021; doi:10.1038/s41585-021-00434-8Radiotheranostic targeting of fPSA (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 9, 2021 Category: Urology & Nephrology Authors: Annette Fenner Source Type: research

Tumour microenvironment markers predict risk of prostate cancer recurrence
Nature Reviews Urology, Published online: 09 February 2021; doi:10.1038/s41585-021-00435-7Tumour microenvironment markers predict risk of prostate cancer recurrence (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 9, 2021 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

High rates of re-intervention after photoselective vaporization of the prostate
Nature Reviews Urology, Published online: 09 February 2021; doi:10.1038/s41585-021-00437-5High rates of re-intervention after photoselective vaporization of the prostate (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 9, 2021 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Monitoring small renal masses is safe in the young
Nature Reviews Urology, Published online: 09 February 2021; doi:10.1038/s41585-021-00436-6Monitoring small renal masses is safe in the young (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 9, 2021 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Kicking the dirt in the hunt for discoveries: pursuing a career in biomedical science
Nature Reviews Urology, Published online: 08 February 2021; doi:10.1038/s41585-021-00433-9In this Worldview, I share a few observations that I have learnt during my career as a biomedical scientist: explore a bit before settling on a place to experimentally dig for your discoveries; recognize that nature is exceedingly complex and that dogma is meant to be broken; allow yourself to take risks and fail; and realize that science is best done with the long view in mind. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 8, 2021 Category: Urology & Nephrology Authors: Nima Sharifi Source Type: research

Transient receptor potential channels in sensory mechanisms of the lower urinary tract
Nature Reviews Urology, Published online: 03 February 2021; doi:10.1038/s41585-021-00428-6Transient receptor potential (TRP) channels have an important role in sensory mechanisms of the lower urinary tract. Vanneste et al. discuss the involvement of TRP channels in normal and abnormal bladder sensations and their potential as therapeutic targets. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 3, 2021 Category: Urology & Nephrology Authors: Matthias Vanneste Andrei Segal Thomas Voets Wouter Everaerts Source Type: research

Promising long-term results with proton therapy for localized prostate cancer
Nature Reviews Urology, Published online: 27 January 2021; doi:10.1038/s41585-021-00429-5The value of proton therapy in managing prostate cancer is not yet defined. A recent study has reported promising long-term results for patients with localized prostate cancer who received proton therapy. However, results from ongoing clinical trials are required before determining the role of proton therapy for this indication. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 27, 2021 Category: Urology & Nephrology Authors: Curtis M. Bryant Bradford S. Hoppe Source Type: research

Adjuvant radiotherapy for node-positive penile cancer
Nature Reviews Urology, Published online: 18 January 2021; doi:10.1038/s41585-021-00430-yAdjuvant radiotherapy for node-positive penile cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 18, 2021 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Is body composition linked to prostate cancer survival?
Nature Reviews Urology, Published online: 13 January 2021; doi:10.1038/s41585-021-00427-7Adiposity and skeletal muscle mass have been shown to be prognostic for mortality in several cancers. In a recent study, CT imaging at diagnosis was used to determine whether components of body composition were associated with survival in men with advanced prostate cancer. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 13, 2021 Category: Urology & Nephrology Authors: Ilona Csizmadi William J. Aronson Source Type: research

Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity
Nature Reviews Urology, Published online: 13 January 2021; doi:10.1038/s41585-020-00417-1Premature ejaculation is thought to affect up to one-third of men, but a considerable proportion of patients do not meet the diagnostic criteria and do not, therefore, receive treatment for their symptoms. In this Perspectives article, the authors propose a new taxonomy for premature ejaculation, to encompass the subclinical disorder and its co-occurrence with erectile dysfunction, with a view to improving patient management. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 13, 2021 Category: Urology & Nephrology Authors: Elena Colonnello Giacomo Ciocca Erika Limoncin Andrea Sansone Emmanuele A. Jannini Source Type: research

The need for standardization of reporting in prostate MRI
Nature Reviews Urology, Published online: 12 January 2021; doi:10.1038/s41585-021-00425-9MRI has become an established tool in the diagnosis, management and treatment of localized prostate cancer. However, standardized guidelines on reporting prostate MRI have not yet been developed. A recent consensus study proposes a certification framework for reporting prostate MRI in the UK. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 12, 2021 Category: Urology & Nephrology Authors: Baris Turkbey Bradford J. Wood Source Type: research

Surgical ergonomics for urologists: a practical guide
Nature Reviews Urology, Published online: 11 January 2021; doi:10.1038/s41585-020-00414-4Surgical ergonomics in urology has been understudied and underemphasized. This Review characterizes the burden of musculoskeletal injury in urologists and focuses on various ergonomic considerations relevant to the urology surgeon. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 11, 2021 Category: Urology & Nephrology Authors: Andrew T. Gabrielson Marisa M. Clifton Christian P. Pavlovich Michael J. Biles Mitchell Huang Jacqueline Agnew Phillip M. Pierorazio Brian R. Matlaga Petar Bajic Zeyad R. Schwen Source Type: research

Defining cisplatin eligibility in patients with muscle-invasive bladder cancer
Nature Reviews Urology, Published online: 11 January 2021; doi:10.1038/s41585-020-00404-6Many patients with muscle-invasive bladder cancer are currently excluded from cisplatin-based neoadjuvant chemotherapy owing to renal impairment. Here, Jiang and colleagues present an update on cisplatin-induced nephrotoxicity in muscle-invasive bladder cancer and highlight a multidisciplinary and patient-centred approach to treatment decision-making. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 11, 2021 Category: Urology & Nephrology Authors: Di Maria Jiang Shilpa Gupta Abhijat Kitchlu Alejandro Meraz-Munoz Scott A. North Nimira S. Alimohamed Normand Blais Srikala S. Sridhar Source Type: research

The emerging role of checkpoint inhibitors for rare genitourinary cancers
Nature Reviews Urology, Published online: 11 January 2021; doi:10.1038/s41585-021-00426-8Rare genitourinary cancers have historically been challenging to treat given the scarcity in incidence, inadequacy of data on treatment and lack of general consensus to guide routine therapy. A phase II multicentre trial shows efficacy of nivolumab and ipilimumab in several cohorts of patients with rare genitourinary cancers. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 11, 2021 Category: Urology & Nephrology Authors: Jeanny B. Aragon-Ching Source Type: research

Partial nephrectomy for patients with limited life expectancy?
Nature Reviews Urology, Published online: 06 January 2021; doi:10.1038/s41585-020-00421-5A new study reports that selected patients with short life expectancy can safely undergo partial nephrectomy with perioperative outcomes that approximate those of patients with long life expectancy. The authors suggest that extensive centre and/or surgeon experience, a robot-assisted approach, and off-clamp and simple enucleation techniques might facilitate favourable outcomes in these challenging patients. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 6, 2021 Category: Urology & Nephrology Authors: Steven C. Campbell Rebecca A. Campbell Source Type: research

Sacral neuromodulation for LUTS has promising long-term outcomes
Nature Reviews Urology, Published online: 06 January 2021; doi:10.1038/s41585-021-00424-wSacral neuromodulation for LUTS has promising long-term outcomes (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 6, 2021 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Contraindications prevent desmopressin use in patients with nocturia
Nature Reviews Urology, Published online: 06 January 2021; doi:10.1038/s41585-021-00423-xContraindications prevent desmopressin use in patients with nocturia (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 6, 2021 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Genetic risk score predicts prostate cancer incidence and mortality
Nature Reviews Urology, Published online: 06 January 2021; doi:10.1038/s41585-021-00422-yGenetic risk score predicts prostate cancer incidence and mortality (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - January 6, 2021 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Organ-sparing surgery in penile cancer: a call for centralization of surgery
Nature Reviews Urology, Published online: 23 December 2020; doi:10.1038/s41585-020-00420-6Organ-sparing surgery for the management of penile cancer is a dogma underpinned by previous research demonstrating no change in cancer-specific survival in cases of local recurrence. However, a new multicentre study of 897 patients treated with glansectomy for penile cancer challenges this view. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 23, 2020 Category: Urology & Nephrology Authors: Paul K. Hegarty Helen Zafirakis Source Type: research

Urinary biomarkers to mitigate diagnostic delay in bladder cancer during the COVID-19 era
Nature Reviews Urology, Published online: 17 December 2020; doi:10.1038/s41585-020-00419-zThe COVID-19 pandemic has resulted in a substantial increase in waiting times for cystoscopies, prompting concerns of delayed diagnoses and substandard surveillance of bladder cancer. Expanding the role of urinary biomarkers in diagnostic and surveillance pathways could be a strategy to address this problem, and several novel biomarkers have shown promise for this purpose. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 17, 2020 Category: Urology & Nephrology Authors: Kenrick Ng Krishna Vinnakota Anand Sharma John Kelly Prokar Dasgupta Nikhil Vasdev Source Type: research

Genomic and phenotypic heterogeneity in prostate cancer
Nature Reviews Urology, Published online: 16 December 2020; doi:10.1038/s41585-020-00400-wThis Review summarizes the manifestations of inter-tumoural and intra-tumoural heterogeneity in primary and metastatic prostate cancer, emphasizing the contribution of genomics studies and discussing the importance of phenotypic changes. The authors also critically discuss the implications for clinical management and research. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 16, 2020 Category: Urology & Nephrology Authors: Michael C. Haffner Wilbert Zwart Martine P. Roudier Lawrence D. True William G. Nelson Jonathan I. Epstein Angelo M. De Marzo Peter S. Nelson Srinivasan Yegnasubramanian Source Type: research

Intravesical therapy goes viral
Nature Reviews Urology, Published online: 15 December 2020; doi:10.1038/s41585-020-00418-0Intravesical therapy goes viral (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 15, 2020 Category: Urology & Nephrology Authors: Peter Sidaway Source Type: research

Supporting Black voices in urology
Nature Reviews Urology, Published online: 14 December 2020; doi:10.1038/s41585-020-00401-9At Nature Reviews Urology, we have pledged to strive towards improving diversity in our field. As a step towards this goal, this Viewpoint presents the experiences of 10 Black urologists. Their stories illustrate the importance of perseverance and emphasize the essential role of community and mentorship to raise up our peers and colleagues, to support and encourage Black urologists and lead to a more diverse field of urology in the future. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 14, 2020 Category: Urology & Nephrology Authors: Tracy M. Downs Ekene Enemchukwu Cheryl T. Lee Kelvin A. Moses Yaw A. Nyame Isaac J. Powell Randy Vince Heinric Williams Shenelle Wilson Samuel L. Washington Source Type: research

Fighting the ‘other pandemic’ — systemic racism in urology
Nature Reviews Urology, Published online: 14 December 2020; doi:10.1038/s41585-020-00406-4In medicine and society exist two pandemics. One, COVID-19, has recently emerged and has been widely acknowledged. The other — systemic racism — has been silently deadly for centuries. Now is the time to recognize the impact of this other pandemic and to eradicate it. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 14, 2020 Category: Urology & Nephrology Authors: Randy A. Vince Jr Kristen R. Scarpato Adam P. Klausner Source Type: research

Publisher Correction: Making love in the time of corona — considering relationships in lockdown
Nature Reviews Urology, Published online: 14 December 2020; doi:10.1038/s41585-020-00415-3Publisher Correction: Making love in the time of corona — considering relationships in lockdown (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 14, 2020 Category: Urology & Nephrology Authors: Marieke Dewitte Chantelle Otten Lauren Walker Source Type: research

MRI-guided active surveillance in prostate cancer: not yet ready for practice
Nature Reviews Urology, Published online: 11 December 2020; doi:10.1038/s41585-020-00416-2Multiparametric MRI enables early detection of progression and reclassification in patients with low-risk prostate cancer on active surveillance and offers the potential to reduce unnecessary biopsies. However, the reliability and reproducibility of MRI-directed surveillance during follow-up is unclear. A recent study highlights the potential and current shortcomings of this approach. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 11, 2020 Category: Urology & Nephrology Authors: Guillaume Ploussard Rapha ële Renard-Penna Source Type: research

Is a targeted biopsy-only approach for prostate cancer diagnosis ready for the prime time?
Nature Reviews Urology, Published online: 04 December 2020; doi:10.1038/s41585-020-00412-6The PRECISION trial demonstrated the ability of using multiparametric MRI to improve the diagnosis of clinically significant prostate cancer whilst reducing over-diagnosis of clinically insignificant cancer compared with systematic biopsy. Concerns remained about patients who were not biopsied owing to negative scans. A new study applies the PRECISION strategy to a contemporary cohort to answer these concerns. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 4, 2020 Category: Urology & Nephrology Authors: Jonathan Sussman Abhinav Sidana Source Type: research

Reduction in ureteral stent-associated symptoms with a customized ‘Suture-Stent’
Nature Reviews Urology, Published online: 01 December 2020; doi:10.1038/s41585-020-00407-3Reduction in ureteral stent-associated symptoms with a customized ‘Suture-Stent’ (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 1, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Artificial intelligence for intrarenal access
Nature Reviews Urology, Published online: 01 December 2020; doi:10.1038/s41585-020-00409-1Artificial intelligence for intrarenal access (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 1, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Machine learning improves antibiotics use
Nature Reviews Urology, Published online: 01 December 2020; doi:10.1038/s41585-020-00413-5Machine learning improves antibiotics use (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 1, 2020 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Reducing routine blood tests for RARP
Nature Reviews Urology, Published online: 01 December 2020; doi:10.1038/s41585-020-00410-8Reducing routine blood tests for RARP (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 1, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Synergistic action of combined PARP and ATR inhibition in prostate cancer with ATM loss
Nature Reviews Urology, Published online: 01 December 2020; doi:10.1038/s41585-020-00408-2Synergistic action of combined PARP and ATR inhibition in prostate cancer with ATM loss (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - December 1, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Does MRI-guided TULSA provide a targeted approach to ablation?
Nature Reviews Urology, Published online: 26 November 2020; doi:10.1038/s41585-020-00403-7MRI-guided transurethral ultrasound ablation is an exciting, minimally invasive technology with the potential to provide targeted ablation of prostate cancer tissue. At 3 years, functional outcomes remain good with 76% remaining free from salvage treatment. Future studies using a focal approach may provide evidence for widespread uptake of this technology. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 26, 2020 Category: Urology & Nephrology Authors: Rohith Arcot Thomas J. Polascik Source Type: research

HPV positivity and radiotherapy outcomes in PSCC
Nature Reviews Urology, Published online: 26 November 2020; doi:10.1038/s41585-020-00411-7HPV positivity and radiotherapy outcomes in PSCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 26, 2020 Category: Urology & Nephrology Authors: Annette Fenner Source Type: research

The biology and rationale of targeting nectin-4 in urothelial carcinoma
Nature Reviews Urology, Published online: 25 November 2020; doi:10.1038/s41585-020-00394-5New and more effective treatments are urgently needed for bladder cancer. This Review discusses the role of nectin-4 as a therapeutic target for enfortumab vedotin (an antibody–drug conjugate) in locally advanced and metastatic urothelial carcinoma and outlines related clinical data. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 25, 2020 Category: Urology & Nephrology Authors: Elisabeth I. Heath Jonathan E. Rosenberg Source Type: research

Retzius-sparing RARP: improving functional outcomes
Nature Reviews Urology, Published online: 25 November 2020; doi:10.1038/s41585-020-00405-5Retzius-sparing prostatectomy is an alternative approach to standard robot-assisted radical prostatectomy. Many surgeons advocate this technique as data suggest that it provides better early functional results than the standard approach without compromising oncological outcomes. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 25, 2020 Category: Urology & Nephrology Authors: Antonio Galfano Aldo Massimo Bocciardi Source Type: research

Revolutionizing care for rare genitourinary tumours
Nature Reviews Urology, Published online: 24 November 2020; doi:10.1038/s41585-020-00402-8Management of rare genitourinary malignancies often depends on individual physicians’ discretion, resulting in non-standardized care. Furthermore, patients experience worse clinical outcomes than patients with common malignancies. Collaborative efforts such as the Global Society of Rare Genitourinary Tumors (GSRGT) are therefore necessary. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 24, 2020 Category: Urology & Nephrology Authors: Andrea Necchi Filippo Pederzoli Marco Bandini Philippe E. Spiess Source Type: research

Sperm ion channels and transporters in male fertility and infertility
Nature Reviews Urology, Published online: 19 November 2020; doi:10.1038/s41585-020-00390-9Mammalian sperm must respond to a variety of cues, and dynamic regulation of ion signalling is, therefore, essential for sperm cells to adapt to their environment. In this Review, the authors describe the ion channels and membrane receptors controlling sperm activity, in particular the principal Ca2+-selective plasma membrane ion channel CatSper, and consider how sperm ion channels and membrane receptors are attractive targets for therapeutics and how these signalling processes might have implications for assisted reproductive technol...
Source: Nature Reviews Urology - November 19, 2020 Category: Urology & Nephrology Authors: Huafeng Wang Luke L. McGoldrick Jean-Ju Chung Source Type: research

Cannabinoid signalling and effects of cannabis on the male reproductive system
Nature Reviews Urology, Published online: 19 November 2020; doi:10.1038/s41585-020-00391-8Many aspects of human male reproduction can be modulated by cannabinoids and endocannabinoids (eCBs). Preclinical studies have shown that the endocannabinoid system (ECS) is involved in negative modulation of testosterone secretion, but the effect of in vivo exposure to cannabinoids on spermatogenesis remains a matter of debate. An improved understanding of the complex crosstalk between cannabinoids and eCBs might enable targeting of the ECS for modulation of human fertility. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 19, 2020 Category: Urology & Nephrology Authors: Mauro Maccarrone Cinzia Rapino Felice Francavilla Arcangelo Barbonetti Source Type: research

Surgical management of high-risk, localized prostate cancer
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00384-7Radical prostatectomy is increasingly used as a first-line treatment for patients with high-risk, localized prostate cancer. Here, Wilkins and colleagues highlight the heterogeneous outcomes of these men and discuss the role of this approach in individualized, multimodal prostate cancer therapy. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Lamont J. Wilkins Jeffrey J. Tosoian Debasish Sundi Ashley E. Ross Dominic Grimberg Eric A. Klein Brian F. Chapin Yaw A. Nyame Source Type: research

Patient-derived tumour models for personalized therapeutics in urological cancers
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00389-2In this Review, van de Merbel et al. provide a comprehensive overview of the current patient-derived tumour models in use for urological cancers and discuss their advantages and limitations, as well as their potential for personalized treatment. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Arjanneke F. van de Merbel Geertje van der Horst Gabri van der Pluijm Source Type: research

Combined immune checkpoint inhibition for high-risk urothelial carcinoma
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00398-1Combined immune checkpoint inhibition for high-risk urothelial carcinoma (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

PIEZO2 in urinary function
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00395-4PIEZO2 in urinary function (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Low prescribing rates of phytotherapy for LUTS
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00397-2Low prescribing rates of phytotherapy for LUTS (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research

Serum MMP7 levels could guide metastatic therapy for prostate cancer
Nature Reviews Urology, Published online: 10 November 2020; doi:10.1038/s41585-020-00396-3Serum MMP7 levels could guide metastatic therapy for prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - November 10, 2020 Category: Urology & Nephrology Authors: Rebecca Tregunna Source Type: research