Mapping immune cell chromatin landscapes in ccRCC
Nature Reviews Urology, Published online: 10 August 2022; doi:10.1038/s41585-022-00646-6Mapping immune cell chromatin landscapes in ccRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 10, 2022 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Race and prostate cancer: genomic landscape
Nature Reviews Urology, Published online: 09 August 2022; doi:10.1038/s41585-022-00622-0In this Review, the authors discuss racial differences in the prevalence of genetic mutations in the main molecular drivers of prostate cancer and provide input regarding the role of genomics in racial disparities observed in prostate cancer outcomes. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 9, 2022 Category: Urology & Nephrology Authors: Camilo Arenas-Gallo Jude Owiredu Ilon Weinstein Patrick Lewicki Spyridon P. Basourakos Randy Vince Jr Bashir Al Hussein Al Awamlh Fredrick R. Schumacher Daniel E. Spratt Christopher E. Barbieri Jonathan E. Shoag Source Type: research

Treating cancer in kidney transplant recipients
Nature Reviews Urology, Published online: 09 August 2022; doi:10.1038/s41585-022-00643-9Treating cancer in kidney transplant recipients (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 9, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

Vaccination to prevent untreatable gonorrhoea
Nature Reviews Urology, Published online: 09 August 2022; doi:10.1038/s41585-022-00645-7Vaccination to prevent untreatable gonorrhoea (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 9, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

MDPs and racial differences in prostate cancer
Nature Reviews Urology, Published online: 09 August 2022; doi:10.1038/s41585-022-00644-8MDPs and racial differences in prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 9, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research

The future of pelvic lymph node dissection for urological malignancies
Nature Reviews Urology, Published online: 03 August 2022; doi:10.1038/s41585-022-00641-xControversies over how, why and when pelvic lymph node dissection (PLND) should be performed persist. Available data suggest that a limited number of patients will experience a curative benefit from PLND, but it remains the most tried and tested diagnostic tool for staging. New techniques aim to improve noninvasive detection of diseased nodes. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 3, 2022 Category: Urology & Nephrology Authors: Gallus B. Ineichen Fiona C. Burkhard Source Type: research

Novel intravesical gemcitabine delivery system (TAR-200) for neoadjuvant treatment of MIBC: context is everything
Nature Reviews Urology, Published online: 02 August 2022; doi:10.1038/s41585-022-00634-wMuscle-invasive bladder cancer (MIBC) remains a deadly disease, despite aggressive surgical and systemic chemotherapeutic treatments. New treatment modalities are needed. A novel intravesicle drug delivery device for neoadjuvant treatment of MIBC has been developed, and preliminary results on the efficacy and safety of this system are available. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - August 2, 2022 Category: Urology & Nephrology Authors: Katherine M. Rodriguez Max Kates Source Type: research

Mutagenic effect of chemotherapy on sperm DNA and implications for family planning
Nature Reviews Urology, Published online: 29 July 2022; doi:10.1038/s41585-022-00625-xSome chemotherapeutic agents can induce distinct mutational signatures in healthy cells in patients with cancer. The effect of such mutational signatures on spermatogenesis is not fully understood but is of great clinical importance for counselling patients diagnosed with cancer planning to start a family after treatment. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 29, 2022 Category: Urology & Nephrology Authors: Ari P. Bernstein Justin Loloi Rohit Reddy Christian Ramsoomair Katherine Campbell Francesco Maura Ola Landgren Daniel Nassau Emad Ibrahim Ranjith Ramasamy Source Type: research

Management of very young fetuses with LUTO
Nature Reviews Urology, Published online: 26 July 2022; doi:10.1038/s41585-022-00636-8Management of very young fetuses with LUTO (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 26, 2022 Category: Urology & Nephrology Authors: Thomas Kohl Source Type: research

Reply to ‘Management of very young fetuses with LUTO’
Nature Reviews Urology, Published online: 26 July 2022; doi:10.1038/s41585-022-00637-7Reply to ‘Management of very young fetuses with LUTO’ (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 26, 2022 Category: Urology & Nephrology Authors: Valentina Capone Nicola Persico Giovanni Montini Source Type: research

The unclear role of PET–CT in localized radiorecurrent prostate cancer
Nature Reviews Urology, Published online: 25 July 2022; doi:10.1038/s41585-022-00635-9Prostate cancer recurrence is common after radical radiotherapy and the increasing use of novel, minimally invasive salvage treatments means that accurate detection and localization of radiorecurrent disease is vital in treatment planning and delivery. PET–CT is increasingly used to detect metastatic disease; however, data regarding its value for identifying and accurately characterizing intraprostatic recurrence need improvement. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 25, 2022 Category: Urology & Nephrology Authors: Alexander Light Hashim U. Ahmed Taimur T. Shah Source Type: research

Immune-based therapies in penile cancer
Nature Reviews Urology, Published online: 18 July 2022; doi:10.1038/s41585-022-00617-xIn this Review, Joshi and colleagues describe the immune landscape of penile cancer, examine existing and novel immune-based therapeutic targets, and discuss the future directions of immune-based therapies in penile cancer based on preclinical and clinical studies. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 18, 2022 Category: Urology & Nephrology Authors: Vidhu B. Joshi Philippe E. Spiess Andrea Necchi Curtis A. Pettaway Jad Chahoud Source Type: research

Control of oncogenic signalling in ccRCC
Nature Reviews Urology, Published online: 13 July 2022; doi:10.1038/s41585-022-00627-9Control of oncogenic signalling in ccRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 13, 2022 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

BAUSing back in Birmingham
Nature Reviews Urology, Published online: 13 July 2022; doi:10.1038/s41585-022-00629-7BAUSing back in Birmingham (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 13, 2022 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

A therapy for men with previously treated mCRPC
Nature Reviews Urology, Published online: 12 July 2022; doi:10.1038/s41585-022-00631-zA therapy for men with previously treated mCRPC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - July 12, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research