Salvage irreversible electroporation for radio-recurrent prostate cancer
Nature Reviews Urology, Published online: 01 March 2023; doi:10.1038/s41585-023-00750-1Focal ablative therapy has emerged as a treatment option in radio-recurrent prostate cancer to obtain local control of disease and spare patients severe salvage-treatment-related complications. Irreversible electroporation holds the potential to become the standard ablative modality in prostate cancer owing to reliable ablation results, the electricity-based effect and an acceptable adverse-effect profile. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 1, 2023 Category: Urology & Nephrology Authors: Matthijs J. Scheltema Athos Katelaris Phillip D. Stricker Source Type: research

Successful mentorship for women in urology — a new era
Nature Reviews Urology, Published online: 01 March 2023; doi:10.1038/s41585-023-00745-yThe number of women entering the historically male-dominated field of urology is growing over time, but women in urology are disproportionately younger than the male counterpart and face unique challenges that require intentionally directed mentorship. In this Comment, some of these issues are discussed from the perspective of both the female mentee and mentor. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - March 1, 2023 Category: Urology & Nephrology Authors: Anne M. Suskind Stacy Tanaka Source Type: research

The past, present and future of women in the United States urological workforce
Nature Reviews Urology, Published online: 27 February 2023; doi:10.1038/s41585-023-00744-zWomen urologists constitute an increasing proportion of the urology workforce in the United States. Considering the projected shortage of urologists over the coming decades, women urologists will have a crucial role in the delivery of urological care. Opportunities for recruitment and retention of women in the field of urology must be highlighted. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 27, 2023 Category: Urology & Nephrology Authors: Catherine S. Nam Amy N. Luckenbaugh Akanksha Mehta Source Type: research

Artificial intelligence in academic writing: a paradigm-shifting technological advance
Nature Reviews Urology, Published online: 24 February 2023; doi:10.1038/s41585-023-00746-xArtificial intelligence (AI) has rapidly become one of the most important and transformative technologies of our time, with applications in virtually every field and industry. Among these applications, academic writing is one of the areas that has experienced perhaps the most rapid development and uptake of AI-based tools and methodologies. We argue that use of AI-based tools for scientific writing should widely be adopted. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 24, 2023 Category: Urology & Nephrology Authors: Roei Golan Rohit Reddy Akhil Muthigi Ranjith Ramasamy Source Type: research

What can urology learn about sponsorship from business and medicine?
Nature Reviews Urology, Published online: 21 February 2023; doi:10.1038/s41585-023-00732-3Sponsorship is the active and intentional use of a person’s influence or leadership status to use political and personal capital to advance a junior colleague’s career both privately and publicly. A sponsor has a seat at the decision-making table and can access the junior colleague’s work and power, and a junior colleague can capitalize on the opportunity quickly, effectively and successfully. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 21, 2023 Category: Urology & Nephrology Authors: Simone Thavaseelan Jay D. Raman Margaret Pearle Source Type: research

Pembrolizumab + axitinib beyond first-line therapy for mRCC
Nature Reviews Urology, Published online: 16 February 2023; doi:10.1038/s41585-023-00743-0Pembrolizumab + axitinib beyond first-line therapy for mRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2023 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Semen quality recovery following COVID-19
Nature Reviews Urology, Published online: 16 February 2023; doi:10.1038/s41585-023-00742-1Semen quality recovery following COVID-19 (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2023 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Semen parameters across testicular cancer stages
Nature Reviews Urology, Published online: 16 February 2023; doi:10.1038/s41585-023-00741-2Semen parameters across testicular cancer stages (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 16, 2023 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

Preclinical models of prostate cancer — modelling androgen dependency and castration resistance in vitro, ex vivo and in vivo
Nature Reviews Urology, Published online: 14 February 2023; doi:10.1038/s41585-023-00726-1Prostate cancer depends on the hormonal environment for growth. In this Review, the authors describe how this hormonal dependency can be studied in preclinical models. Advantages and limitations of these models are discussed to maximize the transfer of knowledge from scientific research to clinical applications. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 14, 2023 Category: Urology & Nephrology Authors: Lucas Germain Camille Lafront Virginie Paquette Bertrand Neveu Jean-S ébastien Paquette Fr édéric Pouliot Étienne Audet-Walsh Source Type: research

GHR expression and prostate cancer proliferation
Nature Reviews Urology, Published online: 13 February 2023; doi:10.1038/s41585-023-00740-3GHR expression and prostate cancer proliferation (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 13, 2023 Category: Urology & Nephrology Authors: Tim Thomas Source Type: research

An epigenomic atlas for RCC
Nature Reviews Urology, Published online: 10 February 2023; doi:10.1038/s41585-023-00736-zAn epigenomic atlas for RCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 10, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

PARP inhibitor response in prostate cancer
Nature Reviews Urology, Published online: 10 February 2023; doi:10.1038/s41585-023-00735-0PARP inhibitor response in prostate cancer (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 10, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Immunoproteasome inhibition in CRPC
Nature Reviews Urology, Published online: 10 February 2023; doi:10.1038/s41585-023-00737-yImmunoproteasome inhibition in CRPC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 10, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Metabolic flexibility in ccRCC
Nature Reviews Urology, Published online: 10 February 2023; doi:10.1038/s41585-023-00734-1Metabolic flexibility in ccRCC (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 10, 2023 Category: Urology & Nephrology Authors: Louise Stone Source Type: research

Human in vitro spermatogenesis as a regenerative therapy — where do we stand?
Nature Reviews Urology, Published online: 07 February 2023; doi:10.1038/s41585-023-00723-4Several approaches have been used to date to reproduce human spermatogenesis in vitro, which, however, mostly result in incomplete differentiation. In this Review, the authors describe advantages and limitations of current technologies for in vitro spermatogenesis. New approaches that could lead to the clinical translation of this technology to treat patients with male factor infertility are also discussed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - February 7, 2023 Category: Urology & Nephrology Authors: Meghan Robinson Sydney Sparanese Luke Witherspoon Ryan Flannigan Source Type: research