The effects of diet on prostate cancer outcomes
Nature Reviews Urology, Published online: 08 June 2022; doi:10.1038/s41585-022-00612-2The highest risk of death from prostate cancer is associated with increased waist circumference, increased blood pressure, hypertension, type 2 diabetes and obesity; thus, therapies that can reduce blood glucose levels have the potential to improve patient outcomes. The therapeutic benefits of low-carbohydrate and fasting-mimicking diets in patients with prostate cancer have been investigated in two recent studies. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - June 8, 2022 Category: Urology & Nephrology Authors: Thomas N. Seyfried Source Type: research
ADT and node inclusion improves salvage radiation
Nature Reviews Urology, Published online: 07 June 2022; doi:10.1038/s41585-022-00614-0ADT and node inclusion improves salvage radiation (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - June 7, 2022 Category: Urology & Nephrology Authors: Diana Romero Source Type: research
Road for inclusion and caring in urology starts at AUA 22
Nature Reviews Urology, Published online: 07 June 2022; doi:10.1038/s41585-022-00616-yRoad for inclusion and caring in urology starts at AUA 22 (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - June 7, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Sexual orientation, gender identity and COVID: a complicated picture
Nature Reviews Urology, Published online: 16 May 2022; doi:10.1038/s41585-022-00609-xSexual orientation, gender identity and COVID: a complicated picture (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 16, 2022 Category: Urology & Nephrology Authors: Annette Fenner Source Type: research
Improving care for transgender and non-binary individuals
Nature Reviews Urology, Published online: 13 May 2022; doi:10.1038/s41585-022-00610-4Improving care for transgender and non-binary individuals (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 13, 2022 Category: Urology & Nephrology Authors: Louise Stone Source Type: research
Complementary roles of surgery and systemic treatment in clear cell renal cell carcinoma
Nature Reviews Urology, Published online: 11 May 2022; doi:10.1038/s41585-022-00592-3Standard-of-care management of renal cell carcinoma (RCC) relies on surgery for low-risk localized disease and systemic treatment for poor-prognosis metastatic tumours, but patients with high-risk localized tumours and with metastatic disease that has a good-to-intermediate prognosis are in a grey area for treatment. In this Review, the authors provide a comprehensive overview of the current knowledge on surgery and systemic treatment in the management of metastatic and localized RCC. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 11, 2022 Category: Urology & Nephrology Authors: Alexandre Ingels Riccardo Campi Umberto Capitanio Daniele Amparore Riccardo Bertolo Umberto Carbonara Selcuk Erdem Önder Kara Tobias Klatte Maximilian C. Kriegmair Michele Marchioni Maria C. Mir Idir Ouza ïd Nicola Pavan Angela Pecoraro Eduard Roussel A Source Type: research
Sexual and reproductive health during COVID-19 — the I-SHARE multi-country survey
Nature Reviews Urology, Published online: 10 May 2022; doi:10.1038/s41585-022-00603-3Reliable information about sexual and reproductive health and service access during coronavirus disease 2019 (COVID-19) are essential. The International Sexual Health and Reproductive Health (I-SHARE) study is led by a multi-country consortium that adopts an open science approach to achieve this goal. Future work will be needed to assess changes in sexual and reproductive health during the lifting of COVID-19 restrictions. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 10, 2022 Category: Urology & Nephrology Authors: Rayner K. J. Tan Kristien Michielsen Linda Campbell Joseph D. Tucker Source Type: research
Evolution of the World Health Organization semen analysis manual: where are we?
Nature Reviews Urology, Published online: 06 May 2022; doi:10.1038/s41585-022-00593-2The sixth edition of the WHO (World Health Organization) semen analysis manual has been released 10 years after the previous edition and includes important updates. In this Perspective article, a comprehensive overview and discussion of the newly released WHO manual are provided. Limitations of routine semen analysis-based infertility assessment and potential solutions to improve male infertility work-up are also discussed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 6, 2022 Category: Urology & Nephrology Authors: Sandro C. Esteves Source Type: research
Prevalence of gender dysphoria in Japan
Nature Reviews Urology, Published online: 05 May 2022; doi:10.1038/s41585-022-00606-0Prevalence of gender dysphoria in Japan (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 5, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Information in gender-affirming vaginoplasty
Nature Reviews Urology, Published online: 05 May 2022; doi:10.1038/s41585-022-00605-1Information in gender-affirming vaginoplasty (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 5, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Benefits of gender-affirming orchiectomy
Nature Reviews Urology, Published online: 05 May 2022; doi:10.1038/s41585-022-00604-2Benefits of gender-affirming orchiectomy (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - May 5, 2022 Category: Urology & Nephrology Authors: Maria Chiara Masone Source Type: research
Quality of life in sexual minorities following prostate cancer treatment
Nature Reviews Urology, Published online: 27 April 2022; doi:10.1038/s41585-022-00601-5Patients with prostate cancer from sexual minority groups experience considerably worse quality of life following prostate cancer treatment than heterosexual patients. Improved inclusivity as well as cultural humility training at the physician, institution and system levels are warranted to address inequalities in quality-of-life outcomes. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 27, 2022 Category: Urology & Nephrology Authors: David J. Benjamin Arash Rezazadeh Source Type: research
Top, bottom or vers? Creating a more equitable health system for sexual and gender minority patients with prostate cancer
Nature Reviews Urology, Published online: 27 April 2022; doi:10.1038/s41585-022-00600-6Limited information exists regarding the effects of prostate cancer therapies on sexual health outcomes in sexual and gender minority patients. As clinicians, scientists and advocates, understanding these outcomes is imperative in order to enable personalized clinical decision-making and to create a more equitable health system. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 27, 2022 Category: Urology & Nephrology Authors: Daniel R. Dickstein Deborah C. Marshall Source Type: research
Regulation and role of CAMKK2 in prostate cancer
Nature Reviews Urology, Published online: 26 April 2022; doi:10.1038/s41585-022-00588-zSince calcium/calmodulin-dependent kinase kinase 2 (CAMKK2) was identified as an androgen-receptor-regulated gene, important functional roles of CAMKK2 in prostate cancer progression have been shown in preclinical models. In this Perspective, the authors present evidence supporting an oncogenic role of CAMKK2, and also discuss mechanisms of regulation and emerging non-cell-autonomous roles of CAMKK2. Moreover, the potential use of CAMKK2 as a biomarker and/or therapeutic target in prostate cancer is discussed. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 26, 2022 Category: Urology & Nephrology Authors: Thomas L. Pulliam Pavithr Goli Dominik Awad Chenchu Lin Sandi R. Wilkenfeld Daniel E. Frigo Source Type: research
Germline testing and genetic counselling in prostate cancer
Nature Reviews Urology, Published online: 21 April 2022; doi:10.1038/s41585-022-00580-7In this Review, Russo and Giri describe and discuss germline testing criteria, genetic testing strategies, genetically informed screening, precision management, delivery of genetic counselling or alternative genetic services and special considerations for men with prostate cancer. (Source: Nature Reviews Urology)
Source: Nature Reviews Urology - April 21, 2022 Category: Urology & Nephrology Authors: Jessica Russo Veda N. Giri Source Type: research
