Progression of Aortic Calcification in Stage 4 –5 Chronic Kidney Disease Patients Transitioning to Dialysis and Transplantation
Conclusion: AAC progresses rapidly in patients with CKD, and ΔAAC is similar across the CKD treatment groups including transplant recipients. The increment rate is associated with mortality and in transplant recipients with the time on the transplant waiting list.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 26, 2021 Category: Urology & Nephrology Source Type: research
< b > The 1918 Influenza Pandemic: Back to the Future? < /b >
Background: It is just over a century since the 1918 flu pandemic, sometimes referred to as the “mother” of pandemics. This brief retrospective of the 1918 pandemic is taken from the viewpoint of the current SARS-CoV-2/COVID-19 pandemic and is based on a short lecture given during the 2021 Virtual Congress of the ERA-EDTA.Summary: This review summarizes and highlights some of the earlier pandemic ’s salient features, some parallels with today, and some potential learnings, bearing in mind that the flu pandemic occurred over 100 years ago at a time of major turmoil during the climax to WWl, and with limited medical ex...
Source: Kidney and Blood Pressure Research - October 18, 2021 Category: Urology & Nephrology Source Type: research
Ultra-Performance Liquid Chromatography-Q-Exactive Orbitrap-Mass Spectrometry Analysis for Metabolic Communication between Heart and Kidney in Adriamycin-Induced Nephropathy Rats
Conclusion: Six metabolic pathways were found to be involved in cardiorenal metabolic communication in an adriamycin-induced nephropathy model, in which alanine, aspartate, and glutamate metabolism may be the metabolic link between the heart and kidney in the development and maintenance of oxidative stress and inflammation. Succinic acid may serve as a key regulatory metabolic switch or marker of cardiac and renal co-injury, as shown in an adriamycin-induced nephropathy model.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 18, 2021 Category: Urology & Nephrology Source Type: research
Pulse Wave Velocity, Central Haemodynamic Parameters, and Markers of Kidney Function in Children
Conclusions: Our study demonstrated a correlation between serum creatinine and PWV in children with combined risk factors for atherosclerosis and probable subclinical kidney damage. Further prospective research is needed to confirm the findings, and thus the preventive role of PWV determination in paediatric nephrology.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 15, 2021 Category: Urology & Nephrology Source Type: research
Retraction Statement
Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 14, 2021 Category: Urology & Nephrology Source Type: research
The Predialysis Serum Sodium Level Modifies the Effect of Hemodialysis Frequency on Left-Ventricular Mass: The Frequent Hemodialysis Network Trials
Conclusion: In the FHN Daily Trial, the favorable effects of frequent HD on left-ventricular hypertrophy were more pronounced among patients with lower predialysis SNa and higher GNa and TIFL. Whether these metrics can be used to identify patients most likely to benefit from frequent HD or other dialytic or nondialytic interventions remains to be determined. Prospective, adequately powered studies studying the effect of GNa reduction on mortality and hospitalization are needed.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 13, 2021 Category: Urology & Nephrology Source Type: research
The Clinical Value of Serum Adropin Level in Early Detection of Diabetic Nephropathy
Conclusions: This study demonstrates that decreased level of adropin is associated with renal dysfunction in patients with type 2 diabetes mellitus. Serum adropin concentrations may be used as a biomarker for early detection of diabetic nephropathy.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 13, 2021 Category: Urology & Nephrology Source Type: research
Screening Novel Drug Candidates for Kidney Renal Clear Cell Carcinoma Treatment: A Study on Differentially Expressed Genes through the Connectivity Map Database
Conclusion: The above results indicated that fedratinib, LY 344864, geldanamycin, AS-605240, and luminespib could be used as candidates for KIRC therapy. The findings from this study will make contributions to the treatment of KIRC in the future.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 11, 2021 Category: Urology & Nephrology Source Type: research
Elevation of LncRNA ENST00000453774.1 Prevents Renal Fibrosis by Upregulating FBN1, IGF1R, and KLF7
Conclusion: These results show FBN1, IGF1R, and KLF7 serve as downstream targets of lnc453774.1, and that lnc453774.1 may protect against renal fibrosis through competing endogenous miRs which target FBN1, IGF1R, and KLF7 mRNAs.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - October 6, 2021 Category: Urology & Nephrology Source Type: research
Association between Serum Uric Acid and Hypertension in Han and Yugur of Gansu Province: The China National Health Survey
Conclusions: SUA was significantly and independently associated with an increased risk of hypertension in Han and Yugur people. Prospective studies are needed to confirm these findings.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - September 10, 2021 Category: Urology & Nephrology Source Type: research
Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels
Conclusion: Sex and extracellular phosphate levels do not affect the impact of Jak1/Stat3 activation on phosphate metabolism.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - September 7, 2021 Category: Urology & Nephrology Source Type: research
Chronic Kidney Disease-Associated Pruritus: A Review
This article will review the current observations and understanding of the postulated pathogenesis of CKD-aP, as well as the evidence for current management strategies.Key Messages: CKD-aP is a common and troubling symptom amongst ESKD patients that is associated with decreased quality of life and poor prognosis. Its exact pathogenesis, at the time of writing, is not well-understood. A stepwise approach is recommended for management. Systematic reviews show the largest body of evidence was found for the effectiveness of gabapentin. Comparison is needed between newly emerging pharmacological agents such as kappa-opioid rece...
Source: Kidney and Blood Pressure Research - September 7, 2021 Category: Urology & Nephrology Source Type: research
Hypertension as a Risk Factor for Contrast-Associated Acute Kidney Injury: A Meta-Analysis Including 2,830,338 Patients
Conclusion: Our meta-analysis confirmed that HT is an independent risk factor for CA-AKI and can be used to identify risk stratification. Physicians should pay more attention toward prevention and treatment of patients with HT in clinical practice.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - September 7, 2021 Category: Urology & Nephrology Source Type: research
Downregulation of < b > < i > Arntl < /i > < /b > mRNA Expression in Women with Hypertension: A Case-Control Study
Conclusions: TheArntl mRNA expression may play an important role in progression of hypertension in women.Kidney Blood Press Res (Source: Kidney and Blood Pressure Research)
Source: Kidney and Blood Pressure Research - September 3, 2021 Category: Urology & Nephrology Source Type: research
