Meeting Report: ISID2023 Tokyo Satellite Meeting. International Symposium on Autoimmunity Targeting the Skin. Pemphigus, Pemphigoid, and Beyond-
After the first memorable meeting of the International Societies for Investigative Dermatology (ISID 2023) held in Tokyo, the International Symposium on Autoimmunity Targeting the Skin – Pemphigus, Pemphigoid, and Beyond – was held at the Mita Campus of Keio University in Tokyo as one of the satellite meetings associated with ISID 2023 (Fig. 1). Regarding the satellite meetings related to the International Investigative Dermatology (IID), the previous form of ISID, Yasuo Kitaj ima organized the Post-IID International Meeting on Autoimmune Bullous Diseases in Otsu in 2008, and Detlef Zillikens organized the Pre-IID Inte...
Source: Journal of Dermatological Science - August 18, 2023 Category: Dermatology Authors: Jun Yamagami, Hayato Takahashi, Masayuki Amagai Source Type: research
Presence of melanin and melanocytes in the human lower lip vermilion
The lips (labia oris) are composed of the hairy skin, vermilion border, vermilion, and oral mucosa. The lip vermilion (LV) is located at the border of the facial skin and oral mucosa [1]. There is considerable histological evidence supporting the presence of melanin and melanocytes in the basal layer of the epidermis. Regarding the vermilion epithelium, the only available evidence is a report of upper LV obtained from infant patients with cleft lip [2]. However, the presence and distribution of melanocytes within the adult vermilion tissue remains unclear. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 17, 2023 Category: Dermatology Authors: Ayumi Kusaka, Megumi Tobiishi, Haruko Yasumori, Ayami Takahashi, Keigo Kawabata, Yoshito Takahashi Source Type: research
Association of lipid abnormalities in the stratum corneum and TGF- ß1 and 2 in colostrum and the development of infantile seborrheic dermatitis: a prospective birth cohort study
Infantile seborrheic dermatitis (ISD) is a common inflammatory skin condition often seen in the first three months of life. Despite its self-limiting course, it is still distressing to parents. Although Malassezia colonization and sebaceous gland (SG) activation is thought to cause ISD, individual susceptibilities, including host epidermal conditions, and immunity have also been suggested to contribute to the pathogenesis of adult seborrheic dermatitis (ASD) [1]. However, the relationship between these factors and ISD development remains unclear. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 8, 2023 Category: Dermatology Authors: Risa Fukuda, Kyongson Pak, Megumi Kiuchi, Naoko Hirata, Ryo Tanaka, Naoko Mochimaru, Mari Mitsui, Yukihiro Ohya, Kazue Yoshida Source Type: research
Editorial board
(Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Source Type: research
Editor's Choice
(Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Source Type: research
Apelin provides an alternative function to estrogen in regulating lymphatic vascular integrity
Dear Editor: (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Authors: Mika Sawane, Enkhtuul Gantumur, Fumitaka Muramatsu, Hiroyasu Kidoya, Nobuyuki Takakura, Kentaro Kajiya Tags: Letter to the Editor Source Type: research
Long non-coding RNA AL136131.3 inhibits hair growth through mediating PPAR γ in androgenetic alopecia
To the editor, (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Authors: Xiao Liu, Yuting Zhang, Ying Tang, Jiayi Wang, Kai Yang, Chunya Ni, Zheng Li, Yue Zhang, Ji ’an Wang, Haiyang Li, Yulong Tang, Yan Huang, Jinfeng Wu, Qingmei Liu, Wenyu Wu, Jinran Lin Tags: Letter to the Editor Source Type: research
Eosinophil-derived galectin-10 upregulates matrix metalloproteinase expression in bullous pemphigoid blisters
Bullous pemphigoid (BP) is an autoimmune bullous disease in which abundant eosinophils accumulate in the blisters. Galectin-10 abounds in the cytoplasm of eosinophils and is released as a result of eosinophil extracellular trap cell death (EETosis). (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Authors: Takahiko Sato, Takahito Chiba, Takeshi Nakahara, Ken Watanabe, Sawako Sakai, Natsuko Noguchi, Mai Noto, Shigeharu Ueki, Michihiro Kono Source Type: research
Detection of a natural antibody targeting the shed ectodomain of BP180 in mice
Pemphigoid diseases are characterized by subepidermal blister formation accompanied by autoantibodies targeting skin component molecules, such as BP180. It is suggested that an epitope –phenotype correlation exists among autoantibodies recognizing BP180. However, it is unclear which regions of BP180 are likely targets for autoantibodies. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Authors: Yosuke Mai, Kentaro Izumi, Shoko Mai, Wataru Nishie, Hideyuki Ujiie Source Type: research
WTAP-Mediated m6A Modification of IFNE is Required for Antiviral Defense in Condyloma Acuminata
IFN- ε is essential in combating viral infections, particularly in epithelial cells and protected mucosal tissues. Its protective effects have been demonstrated against HSV2, Zika virus, HIV and SARS-COV2. However, the specific expression and role of IFN-ε in skin keratinocytes and HPV infection are st ill not fully understood and require further investigation. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - July 19, 2023 Category: Dermatology Authors: Zhichao Gu, Jiaying Liu, Lei Qin, Yong Zhang, Wenya Cui, Huayu Huang, Lian Liu, Yuchun Cao, Huafeng Zhang Source Type: research
Multi-omics Approach Identifies PI3 as a Biomarker for Disease Severity and Hyper-keratinization in Psoriasis
Psoriasis is an immune-mediated inflammatory skin disease. Psoriasis severity evaluation is important for clinicians in the assessment of disease severity and subsequent clinical decision making. However, no objective biomarker is available for accurately evaluating disease severity in psoriasis. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - July 19, 2023 Category: Dermatology Authors: Jingwen Deng, Emmerik Leijten, Yongzhan Zhu, Michel Olde Nordkamp, Shuyan Ye, Juli ëtte Pouw, Weiyang Tao, Deepak Balak, Guangjuan Zheng, Timothy Radstake, Ling Han, José A.M. Borghans, Chuanjian Lu, Aridaman Pandit Source Type: research
Councilor ’s Meeting/General Assembly of Members at International Societies for Investigative Dermatology 2023
Participants: 560 Regular members, including the board of directors, society officers, and members with power of attorney (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - July 7, 2023 Category: Dermatology Authors: Moderators: Drs. Satoshi Fukushima, Tetsuya Honda Source Type: research
GRB2 Serves as a Viable Target Against Skin Fibrosis in Systemic Sclerosis by Regulating Endothelial Cell Apoptosis
Systemic Sclerosis (SSc) is an autoimmune disease characterized by vascular and immune system dysfunction, along with tissue fibrosis. Our previous study found GRB2 was downregulated by salvianolic acid B, a small molecule drug that attenuated skin fibrosis of SSc. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - July 4, 2023 Category: Dermatology Authors: Yan Huang, Han Zhao, Xiangguang Shi, Jing Liu, Jui-Ming Lin, Qianqian Ma, Shuai Jiang, Weilin Pu, Yanyun Ma, Jianlan Liu, Wenyu Wu, Jiucun Wang, Qingmei Liu Source Type: research
Cycloastragenol exerts protective effects against UVB irradiation in human dermal fibroblasts and HaCaT keratinocytes
Cycloastragenol (CAG) is a triterpene aglycone of astragaloside IV that possesses various pharmacological actions including improving telomerase activity, inhibiting inflammation and cell proliferation, inducing apoptosis. (Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - July 3, 2023 Category: Dermatology Authors: Min Hee Yang, Sun Tae Hwang, Jae-Young Um, Kwang Seok Ahn Source Type: research
Editorial board
(Source: Journal of Dermatological Science)
Source: Journal of Dermatological Science - June 28, 2023 Category: Dermatology Source Type: research
