Eosinophil-derived galectin-10 upregulates matrix metalloproteinase expression in bullous pemphigoid blisters

Bullous pemphigoid (BP) is an autoimmune bullous disease in which abundant eosinophils accumulate in the blisters. Galectin-10 abounds in the cytoplasm of eosinophils and is released as a result of eosinophil extracellular trap cell death (EETosis).

Source: Journal of Dermatological Science - August 1, 2023 Category: Dermatology Authors: Takahiko Sato, Takahito Chiba, Takeshi Nakahara, Ken Watanabe, Sawako Sakai, Natsuko Noguchi, Mai Noto, Shigeharu Ueki, Michihiro Kono Source Type: research