Bayesian structural time series, an alternative to Interrupted Time Series in the right circumstances.
Compare two approaches to analyzing time series data – interrupted time series with segmented regression (ITS-SR) and Bayesian structural time series using the CausalImpact R package (BSTS-CI) — highlighting advantages, disadvantages, and implementation considerations. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - October 13, 2023 Category: Epidemiology Authors: Christopher Gianacas, Bette Liu, Martyn Kirk, Gian Luca Di Tanna, Josephine Belcher, Suzanne Blogg, David Muscatello Tags: Original Article Source Type: research

Using PROGRESS-Plus to identify current approaches to the collection and reporting of equity-relevant data: a scoping review
Our objectives were to identify what and how data relating to the social determinants of health are collected and reported in equity-relevant studies and map these data to the PROGRESS-Plus framework. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - October 4, 2023 Category: Epidemiology Authors: Emma L. Karran, Aidan G. Cashin, Trevor Barker, Mark A. Boyd, Alessandro Chiarotto, Omar Dewidar, Vina Mohabir, Jennifer Petkovic, Saurab Sharma, Sinan Tejani, Peter Tugwell, G. Lorimer Moseley Tags: Methodological Considerations Related to Equity, Diversity, and Inclusion in Clinical Epidemiology Source Type: research

Editorial Board
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - October 1, 2023 Category: Epidemiology Source Type: research

Table of Contents
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - October 1, 2023 Category: Epidemiology Source Type: research

Editors ’ Choice: October 2023
In July 2023, the United Nations published their midway report on the implementation of their Sustainable Development Goals [1]. The report makes for dismal reading, as reflected in the subtitle, calling for “…a Rescue Plan for People and Planet.” Eight years into the Sustainable Development Goals, 50% of the 169 targets showed insufficient progress and 30% were considered stagnant or regressed from the baseline. Of the 17 goals, a few key areas highlighted included gender equality, quality jobs, and reduced inequalities. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - October 1, 2023 Category: Epidemiology Authors: Andrea C. Tricco, David Tovey Tags: Editors ’ Choice Source Type: research

Key concepts in clinical epidemiology: the use of the E-value for sensitivity analysis
Observational research designs enable clinicians to investigate topics for which randomized- controlled trials may be difficult to conduct. However, the lack of randomization in observational studies increases the likelihood of confounders introducing bias to study results. Analytical methods such as propensity score matching and regression analysis are employed to reduce the effects of such confounding, mainly by determining characteristics of patient groups and adjusting for measured confounders. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 30, 2023 Category: Epidemiology Authors: William T. Chung, Kevin C. Chung Tags: Commentary Source Type: research

Selection bias as an explanation for the observed protective association of childhood adiposity with breast cancer
Recalled childhood adiposity is inversely associated with breast cancer observationally, including in Mendelian randomization (MR) studies. Breast cancer studies recruited in adulthood only include survivors of childhood adiposity and breast cancer or a competing risk. We assessed recalled childhood adiposity on participant reported sibling and maternal breast cancer to ensure ascertainment of non-survivors. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 29, 2023 Category: Epidemiology Authors: C.M. Schooling, K. Fei, J.V. Zhao Tags: Original Article Source Type: research

Comorbidities were associated with cancer clinical trial discussion and participation: Findings from the HINTS-SEER (2021)
This study examined the association of having comorbidities and patients ’ experiences with clinical trial discussion or actual participation. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 29, 2023 Category: Epidemiology Authors: Youmin Cho, Shaomei Shang, Weijiao Zhou Tags: Methodological Considerations Related to Equity, Diversity, and Inclusion in Clinical Epidemiology Source Type: research

Gynaecological trials frequently exclude people based on their symptoms rather than their condition: A systematic review of Cochrane reviews and their component trials
To identify strategies used in recent randomised controlled trials (RCTs) and their associated Cochrane Reviews where patients with the same gynaecological condition present with different symptoms but would plausibly benefit from a common intervention. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 29, 2023 Category: Epidemiology Authors: Katie Stocking, Andrew Watson, Jamie J. Kirkham, Jack Wilkinson, Andy Vail Tags: Original Article Source Type: research

Critical elements of synthesis questions are incompletely reported: survey of systematic reviews of intervention effects
To examine the characteristics of population, intervention and outcomes groups and the extent to which they were completely reported for each synthesis in a sample of systematic reviews (SRs) of interventions. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 29, 2023 Category: Epidemiology Authors: Miranda S. Cumpston, Joanne E. McKenzie, Rebecca Ryan, James Thomas, Sue E. Brennan Tags: Original Article Source Type: research

GRADE guidance 38: Updated guidance for rating up certainty of evidence due to a dose-response gradient
This updated guidance from the Grading of Recommendations Assessment, Development and Evaluation (GRADE) addresses rating up certainty of evidence due to a dose-response gradient (DRG) observed in synthesis of intervention and exposure studies. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 28, 2023 Category: Epidemiology Authors: M. Hassan Murad, Jos Verbeek, Lukas Schwingshackl, Tommaso Filippini, Marco Vinceti, Elie Akl, Rebecca L. Morgan, Reem A. Mustafa, Dena Zeraatkar, Emily Senerth, Renee Street, Lifeng Lin, Yngve Falck-Ytter, Gordon Guyatt, Holger J. Sch ünemann, for the G Tags: GRADE Guidance Series Source Type: research

Psychometric sensitivity analyses can identify bias related to measurement properties in trials that use patient-reported outcome measures: a secondary analysis of a clinical trial using the disabilities of the arm, shoulder and hand (DASH) questionnaire
Demonstrate psychometric sensitivity analyses for testing the stability of study findings to assumptions made about patient-reported outcome measures (PROMs). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 27, 2023 Category: Epidemiology Authors: Conrad J. Harrison, Anower Hossain, Julie Bruce, Jeremy N. Rodrigues Tags: Original Article Source Type: research

Measuring vaccine protection when the population is mostly vaccinated
This study aims to address limitations in assessing vaccine protection using the classical vaccine effectiveness (VE) measure, especially in contexts where a significant portion of the population is already vaccinated or infected. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 27, 2023 Category: Epidemiology Authors: Yair Goldberg, Ofra Amir, Micha Mandel, Laurence Freedman, Yinon M. Bar-On, Omri Bodenheimer, Ron Milo, Amit Huppert Tags: Original Article Source Type: research

Greater agreement is required to harness the potential of health intelligence: a critical interpretive synthesis
To synthesize existing knowledge on the features of, and approaches to, health intelligence, including definitions, key concepts, frameworks, methods and tools, types of evidence used, and research gaps. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 21, 2023 Category: Epidemiology Authors: Michelle M. Haby, Evelina Chapman, Jorge Ot ávio Maia Barreto, Oscar J. Mujica, Ana Rivière Cinnamond, Roberta Caixeta, Sebastian Garcia-Saiso, Ludovic Reveiz Tags: Review Source Type: research

GRADE concept 6: A novel application of external indirect evidence into GRADE ratings of evidence certainty in Network Meta-analysis
We describe how consideration of external evidence may play an important role in judging certainty in the process of establishing the certainty of the evidence. Our example is a network meta-analysis (NMA) addressing treatment for Ebola virus disease, which informed a World Health Organization (WHO) guideline. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - September 19, 2023 Category: Epidemiology Authors: Qiukui Hao, Ya Gao, Yunli Zhao, M. Hassan Murad, Reem Mustafa, Mohammed T. Ansari, Holger J. Sch ünemann, David M. Rind, Romina Brignardello-Petersen, Gordon Guyatt Tags: GRADE Concept Series Source Type: research