Editorial Board
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 1, 2024 Category: Epidemiology Source Type: research
Table of Contents
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 1, 2024 Category: Epidemiology Source Type: research
Table 0; documenting the steps to go from clinical database to research dataset
Data-driven decision support tools have been increasingly recognised to transform healthcare. However, such tools are often developed on predefined research datasets without adequate knowledge of the origin of this data and how it was selected. How a dataset is extracted from a clinical database can profoundly impact the validity, interpretability and interoperability of the dataset and downstream analyses, yet is rarely reported. Therefore, we present a case study illustrating how a definitive patient list was extracted from a clinical source database and how this can be reported. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 1, 2024 Category: Epidemiology Authors: Jip W.T.M. de Kok, Bas C.T. van Bussel, Ronny Schnabel, Thijs T.W. van Herpt, Rob G.H. Driessen, Daniek A.M. Meijs, Joep A. Goossens, Helen J.M.M. Mertens, Sander M.J. van Kuijk, Laure Wynants, Iwan C.C. van der Horst, Frank van Rosmalen Tags: Original Article Source Type: research
Systematic review and meta-analysis of prognostic characteristics for breast cancers in populations with digital versus film mammography indicate the transition may have increased both early detection and overdiagnosis
Film mammography has replaced digital mammography in breast screening programs globally. This led to a small increase in the rate of detection, but whether the detection of clinically important cancers increased is uncertain. We aimed to assess the impact on tumour characteristics of screen-detected and interval breast cancers. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 1, 2024 Category: Epidemiology Authors: Rachel Farber, Michael L. Marinovich, Audrey Pinna, Nehmat Houssami, Kevin McGeechan, Alexandra Barratt, Katy JL. Bell Tags: Original Article Source Type: research
Restricted Net Treatment Benefit in oncology
The restricted Net Treatment Benefit (rNTB) is a clinically meaningful and tractable estimand of the overall treatment effect assessed in randomized trials when at least one survival endpoint with time restriction is used. Its interpretation does not rely on parametric assumptions such as proportional hazards, can be estimated without bias even in presence of independent right-censoring and can include a pre-specified threshold of minimal clinically relevant difference. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 1, 2024 Category: Epidemiology Authors: Max Piffoux, Brice Ozenne, Julien Peron, Jean-christophe Chiem, Michael De Backer, Marc Buyse Tags: Original Article Source Type: research
Considerations for the Use of Biochemical Laboratory Registry Data in Clinical and Public Health Research
The automation of a wide variety of laboratory equipment and analyses has generated large amounts of laboratory data that can be used for research purposes. It is therefore increasingly important to support researchers, in particular those with no or limited laboratory background, in identifying and handling potential biases and pitfalls associated with use of these data. This commentary reviews five central considerations for researchers who extract and analyze routine biochemical laboratory-generated data from registers, with the aim of improving the quality, accuracy, and transparency of future studies. (Source: Journal...
Source: Journal of Clinical Epidemiology - March 29, 2024 Category: Epidemiology Authors: Lasse M. Obel, Kasper Adelborg, Anton Potteg ård, Henrik T. Sørensen, Mads Nybo Tags: Commentary Source Type: research
Use and reporting of inverse-probability-of-treatment weighting (IPTW) for multi-category treatments in medical research: a systematic review.
Causal inference methods for observational data represent an alternative to randomised controlled trials when they are not feasible or when real-world evidence is sought. Inverse-probability-of-treatment weighting (IPTW) is one of the most popular approaches to account for confounding in observational studies. In medical research, IPTW is mainly applied to estimate the causal effect of a binary treatment, even when the treatment has in fact multiple categories, despite the availability of IPTW estimators for multiple treatment categories. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 29, 2024 Category: Epidemiology Authors: Fran çois Bettega, Monique Mendelson, Clémence Leyrat, Sébastien Bailly Tags: Original Article Source Type: research
The majority of observational studies in leading peer-reviewed medicine journals are not registered and do not have a publicly accessible protocol: a scoping review
Observational studies are not subject to the same requirements as randomised controlled trials such as as registration or publishing a protocol. The aim of this scoping review was to estimate the registration rate of observational studies in leading peer-reviewed medicine journals and to evaluate whether protocols were available in the public domain. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 29, 2024 Category: Epidemiology Authors: Sophie Leducq, Faaris Zaki, Loes M. Hollestein, Christian Apfelbacher, Nikhil Prasanna Ponna, Rishabh Mazmudar, Sonia Gran Tags: Review Source Type: research
Randomized controlled trials of switching to a new medication vs continuing a chronic medication may underestimate the risk of adverse events in those continuing because of asymmetric depletion of susceptibles
For older adults with atrial fibrillation (AF), direct oral anticoagulants (DOACs) reduce a person's risk of stroke and bleeding, compared with vitamin k antagonists (VKAs) [1 –3]. However, a recently published randomized controlled trial (RCT) of frail older adults who were on a VKA and randomized to continue a VKA or switch to a DOAC was stopped early for futility due to greater risk of bleeding in adults switched to a DOAC [4]. Some have interpreted this to mean that VKAs are safer than DOACs in frail older adults [5]. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2024 Category: Epidemiology Authors: Michael Colacci, Afsaneh Raissi, Prachi Ray, Michelle Sholzberg, Kenneth J. Rothman, Michael Fralick Tags: Letter to the Editor Source Type: research
Identification of application and interpretation errors that can occur in pairwise meta-analyses in systematic reviews of interventions: A systematic review
To generate a bank of items describing application and interpretation errors that can arise in pairwise meta-analyses in systematic reviews of interventions. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2024 Category: Epidemiology Authors: Raju Kanukula, Matthew J. Page, Simon L. Turner, Joanne E. McKenzie Tags: Original Article Source Type: research
Randomized controlled trials of switching to a new medication versus continuing a chronic medication may underestimate risk of adverse events in those continuing because of asymmetric depletion of susceptibles
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2024 Category: Epidemiology Authors: Michael Colacci, Afsaneh Raissi, Prachi Ray, Michelle Sholzberg, Kenneth J. Rothman, Michael Fralick Tags: Letter to the Editor Source Type: research
Pilot and Feasibility Trials in Surgery are Incompletely Reported According to the CONSORT Checklist: A Meta-Research Study
Pilot and feasibility studies are not reported completely as per reporting guidelines in fields of study such as nephrology and psychiatric. The reporting completeness of these types of studies in surgery has never been examined. We designed this study to evaluate previously published pilot and feasibility studies in surgery to assess their completeness of reporting. We found that only approximately half of the items in the reporting guideline checklist were routinely reported. This proportion of items reported has not improved since the publication of the reporting guideline checklist. Research factors that were associate...
Source: Journal of Clinical Epidemiology - March 26, 2024 Category: Epidemiology Authors: Tyler McKechnie, Tania Kazi, Austine Wang, Sophia Zhang, Alex Thabane, Keean Nanji, Phillip Staibano, Lily J. Park, Aristithes Doumouras, Cagla Eskicioglu, Lehana Thabane, Sameer Parpia, Mohit Bhandari Tags: Review Source Type: research
Comparative Global Analysis of Stroke Rehabilitation Recommendations Across Income Levels
Successful implementation of stroke rehabilitation guidelines demands high-quality practice standards tailored to targeted sociodemographic contexts. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 26, 2024 Category: Epidemiology Authors: Jaime Eduardo Rodr íguez-Orozco, Carlos Fernando Martínez-Rubio, Eder Moreno-Vargas, Angélica Peña-Ortiz, María Catalina Pizarro-Peñaranda, Estefanía Rojo-Bustamante, Daniel Eduardo Villarreal-García, Hernán Francisco Bayona-Ortiz Tags: Original Article Source Type: research
Consumer involvement in the development and dissemination of chronic kidney disease guidelines: A summary of a meaningful and sustainable approach developed by CARI Guidelines
We describe the framework for involving consumers in the Australian and New Zealand guideline developers in chronic kidney disease (CARI Guidelines). Our framework incorporates consumers at all levels, from identifying topics to include in the guidelines to ongoing involvement in writing guidelines and roles in our organisation ’s administration and governance. The comprehensive approach we have developed has evolved and been adapted according to available resources and feedback from people with lived experience of chronic kidney disease. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 25, 2024 Category: Epidemiology Authors: Nicole Scholes-Robertson, Chandana Guha, Talia Gutman, Martin Howell, Adela Yip, Brydee Cashmore, Ieyesha Roberts, Pamela Lopez-Vargas, Germaine Wong, Robert MacGinley, Anneliese Synnot, Jonathan C. Craig, Allison Jaur é, Rathika Krishnasamy, David J. Tu Tags: Original Article Source Type: research
Validation of case-ascertainment algorithms using health administrative data to identify people who inject drugs in Ontario, Canada
In this study, we validated case-ascertainment algorithms for identifying people who inject drugs using health administrative data in Ontario, Canada. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 22, 2024 Category: Epidemiology Authors: Zo ë R. Greenwald, Dan Werb, Jordan J. Feld, Peter C. Austin, Daniel Fridman, Ahmed M. Bayoumi, Tara Gomes, Claire E. Kendall, Lauren Lapointe-Shaw, Ayden I. Scheim, Sofia R. Bartlett, Eric I. Benchimol, Zachary Bouck, Lisa M. Boucher, Christina Greenawa Tags: Original Article Source Type: research
