Phone reminders did not increase screening uptake more than SMS reminders: a recruitment study-within-a-trial (SWAT)
To compare the response rates and costs of phone call versus short message service (SMS) screening reminders to prospective randomised controlled trial (RCT) participants. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 30, 2019 Category: Epidemiology Authors: Karen Bracken, Anthony Keech, Wendy Hague, Adrienne Kirby, Kristy P. Robledo, Carolyn Allan, Ann Conway, Mark Daniel, Val Gebski, Mathis Grossmann, David J. Handelsman, Warrick Inder, Alicia Jenkins, Robert McLachlan, Bronwyn Stuckey, Bu B. Yeap, Gary Wit Tags: Original Article Source Type: research

Research-on-research studies or methodological studies are primary research
Journal of Clinical Epidemiology has recently published a study of Faggion and Diaz Cavero [1], in which the authors presented types of primary and secondary research. According to the article, secondary research includes two categories —overviews and systematic reviews, whereas primary research includes three categories: human research (e.g., clinical trials, cohort, case series, and so on), animal research, and in vitro research [1]. Although the aim of the study was obviously not to classify all types of research conducted no wadays, this figure glaringly omits classifying the exact type of study that the Fag...
Source: Journal of Clinical Epidemiology - April 29, 2019 Category: Epidemiology Authors: Livia Puljak Tags: Letter to the Editor Source Type: research

Reporting checklist for methodological, that is, research on research studies is urgently needed
Granholm et  al. [1] have written a nice commentary regarding transparent and systematic reporting of meta-epidemiological studies. The authors have responded to the lamentation that editors and reviewers ask authors of methodological studies to fill-out Preferred Reporting Items for Systematic Reviews and Met a-Analyses (PRISMA) reporting guideline checklist [2]. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 29, 2019 Category: Epidemiology Authors: Livia Puljak Tags: Letter to the Editor Source Type: research

Research-on-research studies, or methodological studies, are primary research
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 29, 2019 Category: Epidemiology Authors: Livia Puljak Tags: Letter to the editor Source Type: research

Transparent and systematic reporting of meta-epidemiological studies
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 29, 2019 Category: Epidemiology Authors: Anders Granholm, Carl Thomas Anthon, Anders Perner, Jon Henrik Laake, Morten Hylander M øller Tags: Letter to the editor Source Type: research

Reporting checklist for methodological, i.e. research on research studies is urgently needed
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 29, 2019 Category: Epidemiology Authors: Livia Puljak Tags: Letter to the editor Source Type: research

How can metaresearch be classified?
We would like to thank Dr Puljak for her interest in our article and for providing an interesting point for discussion regarding the classification of the types of primary and secondary research reported in our study. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 23, 2019 Category: Epidemiology Authors: Clovis Mariano Faggion, Karla Tatiana Diaz Tags: Commentary Source Type: research

Reducing Waste and Increasing Value through Embedded Replicability and Reproducibility in Systematic Review Process and Automation
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 23, 2019 Category: Epidemiology Authors: Farhad Shokraneh Tags: Letter to the editor Source Type: research

How can meta-research be classified?
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 23, 2019 Category: Epidemiology Authors: Clovis Mariano Faggion Tags: Commentary Source Type: research

Improvement was needed in the standards of development for cancer core outcome sets
The Core Outcome Set-STAndards for Development (COS-STAD) contains 11 standards (12 criteria) that are deemed to be the minimum design recommendations for all core outcome set (COS) development projects. Cancer is currently the disease area with the highest number of published COS and is a major cause of worldwide morbidity and mortality. The aim of this study was to provide a baseline of cancer COS standards. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 19, 2019 Category: Epidemiology Authors: Elizabeth Gargon, Paula R. Williamson, Jane M. Blazeby, Jamie J. Kirkham Tags: Original Article Source Type: research

Risk of bias assessments for selective reporting were inadequate in the majority of Cochrane reviews
To analyze adequacy of risk of bias (RoB) judgments for selective reporting in Cochrane systematic reviews.. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 19, 2019 Category: Epidemiology Authors: Frano Saric, Ognjen Barcot, Livia Puljak Tags: Original Article Source Type: research

Video strategies improved health professional knowledge across different contexts: a helix counterbalanced randomised controlled study
This study aimed to apply a novel helix counterbalanced randomised controlled trial design to evaluate the effectiveness of video versus written knowledge translation strategies for improving health professional knowledge of evidence provided in scientific journal articles. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 15, 2019 Category: Epidemiology Authors: Mitchell N. Sarkies, Stephen Maloney, Mark Symmons, Terry P. Haines Tags: Original Article Source Type: research

Established search filters may miss studies when identifying randomized controlled trials
The objective of this study was to determine if established RCT literature search filters should include terms for trial phase. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 12, 2019 Category: Epidemiology Authors: Chris Cooper, Jo Varley-Campbell, Patrice Carter Tags: Original Article Source Type: research

Established search filters may miss studies when identifying randomised controlled trials
The objective of this study is to determine if established RCT literature search filters should include terms for trial phase. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 12, 2019 Category: Epidemiology Authors: Chris Cooper, Jo Varley-Campbell, Patrice Carter Tags: Original Article Source Type: research

Risk of bias in nonrandomized studies of interventions showed low inter-rater reliability and challenges in its application
To assess the inter-rater reliability (IRR) and usability of the risk of bias in nonrandomized studies of interventions tool (ROBINS-I). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 11, 2019 Category: Epidemiology Authors: Silvia Minozzi, Michela Cinquini, Silvia Gianola, Greta Castellini, Chiara Gerardi, Rita Banzi Tags: Original Article Source Type: research

Risk of bias in non-randomised studies of interventions (ROBINS-I) showed low inter-rater reliability and challenges in its application
to assess the inter-rater reliability (IRR) and usability of the Risk Of Bias In Non-randomised Studies of Interventions tool (ROBINS-I). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 11, 2019 Category: Epidemiology Authors: Silvia Minozzi, Michela Cinquini, Silvia Gianola, Greta Castellini, Chiara Gerardi, Rita Banzi Tags: Original Article Source Type: research

Identifying and clarifying arguments in a recent debate regarding measures based on memory-based methods
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 4, 2019 Category: Epidemiology Authors: Ralph M. Barnes Tags: Commentary Source Type: research

Including papers in languages other than English in systematic reviews: important, feasible, yet often omitted
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - April 2, 2019 Category: Epidemiology Authors: Sarah Catherine Walpole Tags: Commentary Source Type: research

The statistical significance of meta-analyses is frequently fragile: definition of a Fragility Index for meta-analyses
Meta-analyses inform clinical practice by summarizing treatment effect estimates based on results from several trials. However, the statistical significance of a meta-analysis (ie, whether the pooled treatment effect is statistically significant or not) may rely on the outcome of only a few patients from specific trials in the meta-analysis. We aimed to evaluate the extent to which the statistical significance of meta-analyses can be changed (from statistically significant to non-significant, or vice-versa) after modifying the event status of patients in specific arms of specific trials. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 30, 2019 Category: Epidemiology Authors: Ignacio Atal, Rapha ël Porcher, Isabelle Boutron, Philippe Ravaud Tags: Original Article Source Type: research

Expert panel diagnosis demonstrated high reproducibility as reference standard in infectious diseases
If a gold standard is lacking in a diagnostic test accuracy study, expert diagnosis is frequently used as reference standard. However, inter- and intra-observer agreements are imperfect. The aim of this study was to quantify the reproducibility of a panel diagnosis for pediatric infectious diseases. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 28, 2019 Category: Epidemiology Authors: Chantal B. van Houten, Christiana A. Naaktgeboren, Liat Ashkenazi-Hoffnung, Shai Ashkenazi, Wim Avis, Irena Chistyakov, Teresa Corigliano, Annick Galetto, Iker Gangoiti, Alain Gervaix, Daniel Glikman, Inga Ivaskeviciene, Amir A. Kuperman, Laurence Lacroix Tags: Original Article Source Type: research

Following Cochrane review protocols to completion 10  years later: a retrospective cohort study and author survey
We analyzed patterns of publication of Cochrane review protocols (CRPs). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2019 Category: Epidemiology Authors: Edita Runjic, Dalibora Behmen, Dawid Pieper, Tim Mathes, Andrea C. Tricco, David Moher, Livia Puljak Tags: Original Article Source Type: research

Following Cochrane review protocols to completion ten years later: a retrospective cohort study and author survey
We analyzed patterns of publication of Cochrane review protocols (CRPs). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2019 Category: Epidemiology Authors: Edita Runjic, Dalibora Behmen, Dawid Pieper, Tim Mathes, Andrea C. Tricco, David Moher, Livia Puljak Tags: Original Article Source Type: research

Delphi Procedure In Core Outcome Set Development: Rating Scale And Consensus Criteria Determined Outcome Selection
To compare two different rating scales within one Delphi study for defining consensus in core outcome set development and to explore the influence of consensus criteria on the outcome selection. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 25, 2019 Category: Epidemiology Authors: Dorien De Meyer, Jan Kottner, Hilde Beele, Jochen Schmitt, Toni Lange, Ann Van Hecke, Sofie Verhaeghe, Dimitri Beeckman Tags: Original Article Source Type: research

Improving the content validity of the mixed methods appraisal tool: a  modified e-Delphi study
This study aimed to improve the content validity of three of the five categories of studies in the MMAT by identifying relevant methodological criteria for appraising the quality of qualitative, survey, and mixed methods studies. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 21, 2019 Category: Epidemiology Authors: Quan Nha Hong, Pierre Pluye, Sergi F àbregues, Gillian Bartlett, Felicity Boardman, Margaret Cargo, Pierre Dagenais, Marie-Pierre Gagnon, Frances Griffiths, Belinda Nicolau, Alicia O’Cathain, Marie-Claude Rousseau, Isabelle Vedel Tags: Original Article Source Type: research

Improving the content validity of the Mixed Methods Appraisal Tool (MMAT): a modified e-Delphi study
This study aimed to improve the content validity of three of the five categories of studies in the MMAT by identifying relevant methodological criteria for appraising the quality of qualitative, survey and mixed methods studies. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 21, 2019 Category: Epidemiology Authors: Quan Nha hong, Pierre Pluye, Sergi F àbregues, Gillian Bartlett, Felicity Boardman, Margaret Cargo, Pierre Dagenais, Gagnon Marie-Pierre, Frances Griffiths, Belinda Nicolau, Alicia O’cathain, Rousseau Marie-Claude, Isabelle Vedel Tags: Original Article Source Type: research

The number needed to treat in pairwise and network meta-analysis and its graphical representation
To present ways to graphically represent a number needed to treat (NNT) in (network) meta-analysis (NMA). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 21, 2019 Category: Epidemiology Authors: Areti Angeliki Veroniki, Ralf Bender, Paul Glasziou, Sharon E. Straus, Andrea C. Tricco Tags: Original Article Source Type: research

There are good clinical, scientific, and social reasons to strengthen links between biomedical and environmental research
Clinical epidemiology rarely addresses biological, clinical, epidemiological, environmental, economic and other social and scientific issues posed by environmental chemical contaminants such as endocrine disrupting chemicals. There is a considerable gap between research and practice in clinical medicine and in environmental health. Organizations often fail to appreciate the human and economic costs of the diseases that environmental chemical contaminants contribute to cause. Also, the relative lack of attention to environmental causes of disease by researchers in medicine and clinical epidemiology cannot be explained just ...
Source: Journal of Clinical Epidemiology - March 21, 2019 Category: Epidemiology Authors: Miquel Porta, Laura N. Vandenberg Tags: Commentary Source Type: research

Corrigendum to “Studies reporting ROC curves of diagnostic and prediction data were incorporated into meta-analyses using corresponding odds ratios” [J Clin Epidemiol. 2007 May;60(5):530-4]
In the above-mentioned article, a typographical error was noticed in the definition of Q2 appearing at the bottom of page 531. AUC in the numerator should be squared. The correct definition should read: Q2  = 2 AUC2/(1 + AUC). The subsequent numerical results in our paper used the correct definition and are unaffected by the typo. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Authors: S.D. Walter, T. Sinuff Tags: Corrigendum Source Type: research

Research without good questions is a waste
Good clinical epidemiological methodology is important, but it is a necessary, not sufficient condition for good research. Original ideas, creativity, clinical and scientific perceptiveness, extensive subject matter expertise and well-prepared questions and hypotheses are the starting point for scientific progress; methodology is the craft to harvest the resulting new knowledge. Both ingredients need to be present for research to succeed and make a difference. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Authors: J. Andre Knottnerus, Peter Tugwell Tags: Editorial Source Type: research

Cover 2 Editorial Board
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Source Type: research

Table of Contents
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Source Type: research

Forcing dichotomous disease classification from reference standards leads to bias in diagnostic accuracy estimates: A simulation study
The objective of this study was to study the impact of ignoring uncertainty by forcing dichotomous classification (presence or absence) of the target disease on estimates of diagnostic accuracy of an index test. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Authors: Kevin Jenniskens, Christiana A. Naaktgeboren, Johannes B. Reitsma, Lotty Hooft, Karel G.M. Moons, Maarten van Smeden Tags: Original Article Source Type: research

Forcing dichotomous disease classification from reference standards lead to bias in diagnostic accuracy estimates: a simulation study
To study the impact of ignoring uncertainty by forcing dichotomous classification (presence or absence) of the target disease on estimates of diagnostic accuracy of an index test. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Authors: Kevin Jenniskens, Christiana A. Naaktgeboren, Johannes B. Reitsma, Lotty Hooft, Karel G.M. Moons, Maarten van Smeden Tags: Original Article Source Type: research

An overview of systematic reviews found suboptimal reporting and methodological limitations of mediation studies investigating causal mechanisms
To investigate whether systematic reviews of mediation studies identify limitations in reporting quality and methodological conduct. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 20, 2019 Category: Epidemiology Authors: Aidan G. Cashin, Hopin Lee, Sarah E. Lamb, Sally Hopewell, Gemma Mansell, Christopher M. Williams, Steven J. Kamper, Nicholas Henschke, James H. McAuley Tags: Review Source Type: research

The proportion of missing data should not be used to guide decisions on multiple imputation
Researchers are concerned whether multiple imputation (MI) or complete case analysis (CCA) should be used when a large proportion of data are missing. We aimed to provide guidance for drawing conclusions from data with a large proportion of missingness. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 13, 2019 Category: Epidemiology Authors: Paul Madley-Dowd, Rachael Hughes, Kate Tilling, Jon Heron Tags: Original Article Source Type: research

Most noninferiority trials were not designed to preserve active comparator treatment effects
To evaluate whether noninferiority trials are designed to adequately preserve the historical treatment effect of their active comparators. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 8, 2019 Category: Epidemiology Authors: Michael Tsui, Sunita Rehal, Vipul Jairath, Brennan C. Kahan Tags: Original Article Source Type: research

Rounding, but not randomization method, non-normality, or correlation, affected baseline P-value distributions in randomized trials
To investigate whether comparing observed with expected P-value distributions for baseline continuous variables in randomized controlled trials (RCTs) might be limited by randomization methods, normality and correlation of variables, or calculation of P-values from rounded summary statistics. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 8, 2019 Category: Epidemiology Authors: Mark J. Bolland, Greg D. Gamble, Alison Avenell, Andrew Grey Tags: Original Article Source Type: research

Most non-inferiority trials were not designed to preserve active comparator treatment effects
To evaluate whether non-inferiority trials are designed to adequately preserve the historical treatment effect of their active comparators. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 8, 2019 Category: Epidemiology Authors: Michael Tsui, Sunita Rehal, Vipul Jairath, Brennan C. Kahan Tags: Original Article Source Type: research

Rounding, but not randomisation method, non-normality, or correlation, affected baseline p-value distributions in randomised trials
To investigate whether comparing observed with expected p-value distributions for baseline continuous variables in randomised controlled trials (RCTs) might be limited by randomisation methods, normality and correlation of variables, or calculation of p-values from rounded summary statistics. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 8, 2019 Category: Epidemiology Authors: Mark J. Bolland, Greg D. Gamble, Alison Avenell, Andrew Grey Tags: Original Article Source Type: research

The risk of conclusion change in systematic review updates can be estimated by learning from a database of published examples
To determine which systematic review characteristics are needed to estimate the risk of conclusion change in systematic review updates. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 5, 2019 Category: Epidemiology Authors: Rabia Bashir, Didi Surian, Adam G. Dunn Tags: Original Article Source Type: research

The Selection of Comparators for Randomized Controlled Trials of Health-Related Behavioral Interventions: Recommendations of an NIH Expert Panel
To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 1, 2019 Category: Epidemiology Authors: Kenneth E. Freedland, Abby C. King, Walter T. Ambrosius, Evan Mayo-Wilson, David C. Mohr, Susan M. Czajkowski, Lehana Thabane, Linda M. Collins, George W. Rebok, Shaun P. Treweek, Thomas D. Cook, Jack D. Edinger, Catherine M. Stoney, Rebecca A. Campo, Deb Tags: Review Source Type: research

Cover 2 Editorial Board
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 1, 2019 Category: Epidemiology Source Type: research

Table of Contents
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 1, 2019 Category: Epidemiology Source Type: research

Stepped wedge designs are coming of age in clinical epidemiology
An important step toward the coming of age of the stepped wedge design has been the publication of a Stepped Wedge Cluster Randomised Trial extension to CONSORT [1]. This design has definite ethical and logistic advantages so needs to be in the research methods armamentarium. However for this design to be accepted by those making practice and policy decisions it is important that they be reassured that this design has been conducted in a rigorous manner. The development of consensus reporting guidelines is the first step but such guidelines then need to be ‘road-tested’ to ensure their feasibility and accuracy....
Source: Journal of Clinical Epidemiology - March 1, 2019 Category: Epidemiology Authors: Peter Tugwell, J. Andr é Knottnerus Tags: Editorial Source Type: research

Comparison of non-Cochrane systematic reviews and their published protocols: Differences occurred frequently but were seldom explained
To quantify the prevalence of differences in the reported methods between non-Cochrane systematic reviews (SRs) and their protocols and the extent to which these were reported and explained. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 26, 2019 Category: Epidemiology Authors: Nadja Koensgen, Tanja Rombey, Katharina Allers, Tim Mathes, Falk Hoffmann, Dawid Pieper Tags: Original Article Source Type: research

A highly structured decision-making process results in GRADE factors having primary influence on how guidelines panels develop clinical recommendations
The determinants of practice guideline panels ’ recommendations remain uncertain. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 16, 2019 Category: Epidemiology Authors: Benjamin Djulbegovic, Tea Reljic, Shira Elqayam, Adam Cuker, Iztok Hozo, Qi Zhou, Shelly-Anne Li, Paul Alexander, Robby Nieuwlaat, Wojtek Wiercioch, Holger Sch ünemann, Gordon Guyatt Tags: Original Article Source Type: research

Structured decision-making drives guidelines panels' recommendations “for” but not “against” health interventions
The objective of this study was to investigate factors considered by members of 8 panels convened by the American Society of Hematology (ASH) to develop guidelines using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 16, 2019 Category: Epidemiology Authors: Benjamin Djulbegovic, Tea Reljic, Shira Elqayam, Adam Cuker, Iztok Hozo, Qi Zhou, Shelly-Anne Li, Paul Alexander, Robby Nieuwlaat, Wojtek Wiercioch, Holger Sch ünemann, Gordon Guyatt Tags: Original Article Source Type: research

A scoping review provided a framework for new ways of doing research through mobilizing collective intelligence
New forms of research involving collective intelligence (CI) of diverse individuals mobilized through crowdsourcing is successfully emerging in various fields. This scoping review aimed to describe these methods across different fields and propose a framework for implementation. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 14, 2019 Category: Epidemiology Authors: Van Thu Nguyen, Mehdi Benchoufi, BridgetYoung, Lina Ghosn, Philippe Ravaud, Isabelle Boutron Tags: Original Article Source Type: research

Decision making about healthcare-related tests and diagnostic test strategies: what “The death of Ivan Ilyich” teaches us
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 14, 2019 Category: Epidemiology Authors: Paulo Schiavom Duarte Tags: Letter to the editor Source Type: research

Should a systematic review be tested for reproducibility before its publication?
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 14, 2019 Category: Epidemiology Authors: Clovis Mariano Faggion Tags: Letter to the editor Source Type: research