Vital signs-based deterioration prediction model assumptions can lead to losses in prediction performance
Vital signs-based models are complicated by repeated measures per patient and frequently missing data. This paper investigated impacts of common vital signs modelling assumptions during clinical deterioration prediction model development. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - May 26, 2023 Category: Epidemiology Authors: Robin Blythe, Rex Parsons, Adrian G. Barnett, Steven M. McPhail, Nicole M. White Tags: Original Article Source Type: research

Published registered reports are rare, limited to one journal group, and inadequate for randomized controlled trials in the clinical field
Registered reports (RR) is a publication format implying a peer-review of the protocol before the start of the study, followed by an in-principle acceptance (IPA) by the journal before the study starts. We aimed to describe randomized controlled trials (RCTs) in the clinical field published as RR. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - May 26, 2023 Category: Epidemiology Authors: Norah Anthony, Antoine Tisseaux, Florian Naudet Tags: Original Article Source Type: research

Published registry-based pharmacoepidemiologic associations show limited concordance with agnostic medication-wide analyses
To assess how the results of published national registry-based pharmacoepidemiology studies (where select associations are of interest) compare with an agnostic medication-wide approach (where all possible drug associations are tested). (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - May 22, 2023 Category: Epidemiology Authors: Cathrine Axfors, Chirag J. Patel, John P.A. Ioannidis Tags: Original Article Source Type: research

Scientists ’ Perception of Pilot Study Quality Was Influenced by Statistical Significance and Study Design
Preliminary studies play a key role in developing large-scale interventions but may be held to higher or lower scientific standards during the peer review process because of their preliminary study status. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - May 20, 2023 Category: Epidemiology Authors: Lauren von Klinggraeff, Sarah Burkart, Christopher D. Pfledderer, Md. Nasim Saba Nishat, Bridget Armstrong, R. Glenn Weaver, Alexander McLain, Michael W. Beets Tags: Original Article Source Type: research

Weaving First Nations, Inuit, and M étis Principles and Values into Health Research Processes
In the Spring of 2021, a research team from the Dalla Lana School of Public Health completed environmental scans on nine key health-related topics to develop an anti-Indigenous racism strategy for health systems in Toronto, Ontario, Canada. To ensure we (Indigenous and non-Indigenous researchers) were respecting First Nations, Inuit, and M étis peoples, cultures, worldviews, and research methods, we weaved three frameworks of Indigenous values and principles together to create a conceptual foundation for undertaking the environmental scans. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - May 20, 2023 Category: Epidemiology Authors: Angela Mashford-Pringle, Claire Hiscock, Emma Janet Rice, Bryanna Scott Tags: Original Article Source Type: research