GRADE guidance 38: Updated guidance for rating up certainty of evidence due to a dose-response gradient

This updated guidance from the Grading of Recommendations Assessment, Development and Evaluation (GRADE) addresses rating up certainty of evidence due to a dose-response gradient (DRG) observed in synthesis of intervention and exposure studies.

Source: Journal of Clinical Epidemiology - September 28, 2023 Category: Epidemiology Authors: M. Hassan Murad, Jos Verbeek, Lukas Schwingshackl, Tommaso Filippini, Marco Vinceti, Elie Akl, Rebecca L. Morgan, Reem A. Mustafa, Dena Zeraatkar, Emily Senerth, Renee Street, Lifeng Lin, Yngve Falck-Ytter, Gordon Guyatt, Holger J. Sch ünemann, for the G Tags: GRADE Guidance Series Source Type: research