Motivations for investigating health inequities in observational epidemiology: a content analysis of 320 studies
To enhance equity in clinical and epidemiological research, it is crucial to understand researcher motivations for conducting equity-relevant studies. Therefore, we evaluated author motivations in a randomly selected sample of equity-relevant observational studies published during the COVID-19 pandemic. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 16, 2024 Category: Epidemiology Authors: Omar Dewidar, Georgia McHale, Ali Al Zubaidi, Mostafa Bondok, Leenah Abdelrazeq, Jimmy Huang, Alyssa Jearvis, Khadija Aliyeva, Amjad Alghamyan, Fatima Jahel, Regina Greer-Smith, Janice Tufte, Lucy C. Barker, Nour Elmestekawy, Melissa K. Sharp, Tanya Horsl Tags: EDI series Source Type: research
Effect of statin use for the primary prevention of cardiovascular disease among older adults: A cautionary tale concerning target trials emulation
Evidence concerning the effect of statins in primary prevention of cardiovascular disease (CVD) among older adults is lacking. Using Quebec population-wide administrative data, we emulated a hypothetical randomized trial including older adults>65 years on April 1st, 2013, with no CVD history and no statin use in the previous year. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 15, 2024 Category: Epidemiology Authors: Miceline M ésidor, Caroline Sirois, Jason Robert Guertin, Mireille E. Schnitzer, Bernard Candas, Claudia Blais, Benoit Cossette, Paul Poirier, James M. Brophy, Lisa Lix, Mina Tadrous, Awa Diop, Denis Hamel, Denis Talbot Tags: Original Article Source Type: research
Voluntary transparency of sponsors of medicines clinical trials is exceptional
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 14, 2024 Category: Epidemiology Authors: Rafael Dal-R é Tags: Letter to the Editor Source Type: research
A brief note on the common (fixed)-effect meta-analysis model
Meta-analysis is a statistical method used to combine results from multiple studies, providing a quantitative summary of their findings. One of the fundamental decisions in conducting a meta-analysis is choosing an appropriate model to estimate the overall effect size and its confidence interval. In this article, we focus on the common-effect (also referred to as the fixed-effect) model, and in a companion article, the random-effects model. These models are the two prevailing meta-analysis models employed in the literature. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 13, 2024 Category: Epidemiology Authors: Areti Angeliki Veroniki, Joanne E. McKenzie Tags: Commentary Source Type: research
Adequacy of clinical guideline recommendations for patients with low-risk cancer managed with monitoring: Systematic review
Plain language summary: More people are diagnosed with low-risk cancer because of advances in technology and cancer awareness. Many of these cancers can be monitored instead of treated. Guidelines are an important tool that clinicians use to help them make monitoring decisions. We found that guidelines had different monitoring recommendations based on different kinds of evidence. Other than for prostate cancer, many guidelines relied on expert opinion to support their recommendations because there are no large trials that assess monitoring in other cancer sites. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 13, 2024 Category: Epidemiology Authors: Kiana Collins, Claire Friedemann Smith, Tori Ford, Nia Roberts, Brian D. Nicholson, Jason Oke Tags: Original Article Source Type: research
Reporting guidelines for traditional Chinese medicine could be improved: A cross-sectional study
The aim of this study is to identify available reporting guidelines for traditional Chinese medicine (TCM), delineate their fundamental characteristics, assess the scientific rigor of their development process, and evaluate their dissemination. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 13, 2024 Category: Epidemiology Authors: Xuanlin Li, Tengyue Wang, Weiman Shi, Yanfang Ma, Qi Wang, Donghai Zhou, Qiaoding Dai, Chengping Wen, Yaolong Chen, Lin Huang Tags: Original Article Source Type: research
Grilling the data: Application of specification curve analysis to red meat and all-cause mortality
To present an application of specification curve analysis —a novel analytic method that involves defining and implementing all plausible and valid analytic approaches for addressing a research question—to nutritional epidemiology. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 12, 2024 Category: Epidemiology Authors: Yumin Wang, Tyler Pitre, Joshua D. Wallach, Russell J. de Souza, Tanvir Jassal, Dennis Bier, Chirag J. Patel, Dena Zeraatkar Tags: Original Article Source Type: research
The GRADE Working Group and CINeMA approaches provided inconsistent certainty of evidence ratings for a network meta-analysis of opioids for chronic noncancer pain
Assessment of the certainty of evidence (CoE) from network meta-analysis is critical to convey the strength of inferences for clinical decision-making. Both the GRADE Working Group (GWG) and the CINeMA framework have been designed to assess the CoE of treatment effects informed by network meta-analysis; however, the concordance of results is uncertain. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 7, 2024 Category: Epidemiology Authors: Atefeh Noori, Behnam Sadeghirad, Lehana Thabane, Mohit Bhandari, Gordon H. Guyatt, Jason W. Busse Tags: Other GRADE Papers Source Type: research
Recording harms in randomised controlled trials of behaviour change interventions: a scoping review and map of the evidence
Randomised controlled trials evaluate diverse interventions. This can include medical interventions such as drugs or surgical procedures, or behaviour change interventions that aim to change a habit, belief, or attitude to improve health e.g., healthy eating, psychological wellbeing. Harms are often recorded poorly or inconsistently within randomised controlled trials of behaviour change interventions. This scoping review aimed to collate and describe literature on categories, definitions, and mechanisms of harms from behaviour change interventions; methods of identifying plausible harms; and recommendations for recording ...
Source: Journal of Clinical Epidemiology - February 6, 2024 Category: Epidemiology Authors: Diana Papaioannou, Sienna Hamer-Kiwacz, Cara Mooney, Cindy Cooper, Alicia O ’Cathain, Kirsty Sprange, Gwenllian Moody Tags: Review Source Type: research
External validation of six COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting
To systematically evaluate the performance of COVID-19 prognostic models and scores for mortality risk in older populations across three healthcare settings: hospitals, primary care, and nursing homes. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 2, 2024 Category: Epidemiology Authors: Anum Zahra, Maarten van Smeden, Evertine J. Abbink, Jesse M. van den Berg, Marieke T. Blom, Carline J. van den Dries, Jacobijn Gussekloo, Fenne Wouters, Karlijn J. Joling, Ren é Melis, Simon P. Mooijaart, Jeannette B. Peters, Harmke A. Polinder-Bos, Bas Tags: Original Article Source Type: research
Time points of outcome are often neglected in acupuncture meta-analyses: A methodological survey
To systematically understand the transparency of outcome measurement time point reporting in meta-analyses of acupuncture. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 2, 2024 Category: Epidemiology Authors: Xiaoying Zhong, Jiaxin Liu, Huanwen Liu, Honglai Zhang Tags: Original Article Source Type: research
Editorial Board
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 1, 2024 Category: Epidemiology Source Type: research
Table of Contents
(Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - February 1, 2024 Category: Epidemiology Source Type: research
February 2024 Editors ’ Choice
In the February issue of the Journal of Clinical Epidemiology, four papers highlight the importance of the role of the librarian (or information specialists) within evidence synthesis. The first focuses on challenges searching the literature to identify methodological research [1]; Searching a methods topic: practical challenges and implications for search design, Journal of Clinical Epidemiology, February 2024, 11,201), whereas the second describes the process of searching the literature in living reviews [2]; Optimizing process and methods for a living systematic review —30 search updates and 3 review updates later, Jo...
Source: Journal of Clinical Epidemiology - February 1, 2024 Category: Epidemiology Authors: Andrea C. Tricco, Jessie McGowan, David Tovey Tags: Editors' Choice Source Type: research
Estimates of sensitivity and specificity of serological tests for SARS-CoV-2 specific antibodies using a Bayesian latent class model approach
In this study, we aimed to assess how accurately serological tests can detect antibodies (IgM and IgG) specific for SARS-CoV-2, the virus that causes COVID-19. As there is no perfect standard for comparison, we applied a statistical analysis called Bayesian latent class models. This analysis allowed us to estimate the sensitivity (true positive rate) and specificity (true negative rate) of the tests for IgM and IgG. We performed three additional analyses to compare the results obtained through different methods, including an analysis that considers a previous molecular diagnosis the gold standard. To do so, we considered s...
Source: Journal of Clinical Epidemiology - January 31, 2024 Category: Epidemiology Authors: Joana P. Costa, Paula Meireles, Eleftherios Meletis, Polychronis Kostoulas, Milton Severo Tags: Original Article Source Type: research
