Levels of end-tidal carbon dioxide are low despite normal respiratory rate in individuals with long
COVID
Description unavailable (Source: Journal of Breath Research)
Source: Journal of Breath Research - December 8, 2021 Category: Respiratory Medicine Authors: Jamie Wood, Laura Tabacof, Jenna Tosto-Mancuso, Dayna McCarthy, Amy Kontorovich and David Putrino Source Type: research
Differentiation of aspirated nasal air from room air using analysis with a differential mobility
spectrometry-based electronic nose: a proof-of-concept study
This study reports the collection of nasal air by
aspiration and the subsequent analysis of the collected air using a differential mobility
spectrometer. We collected nasal air from ten volunteers into breath collecting bags and compared
them to bags of room air and the air aspirated through the device. Distance and dissimilarity
metrics between the sample type... (Source: Journal of Breath Research)
Source: Journal of Breath Research - December 2, 2021 Category: Respiratory Medicine Authors: Jussi Virtanen, Anna Anttalainen, Jaakko Ormiskangas, Markus Karjalainen, Anton Kontunen, Markus Rautiainen, Niku Oksala, Ilkka Kivek äs and Antti Roine Source Type: research
The variability of volatile organic compounds in the indoor air of clinical environments
The development of clinical breath-analysis is confounded by the variability of background volatile
organic compounds (VOCs). Reliable interpretation of clinical breath-analysis at individual, and
cohort levels requires characterisation of clinical-VOC levels and exposures. Active-sampling with
thermal-desorption/gas chromatography-mass spectrometry recorded and evaluated VOC concentrations in
245 samples of indoor air from three sites in a large National Health Service (NHS) provider trust
in the UK over 27 months. Data deconvolution, alignment and clustering isolated 7344 features
attributable to VOC and described ...
Source: Journal of Breath Research - December 2, 2021 Category: Respiratory Medicine Authors: Dahlia Salman, Wadah Ibrahim, Amisha Kanabar, Abigail Joyce, Bo Zhao, Amisha Singapuri, Michael Wilde, Rebecca L Cordell, Teresa McNally, Dorota Ruszkiewicz, Andria Hadjithekli, Robert Free, Neil Greening, Erol A Gaillard, Caroline Beardsmore, Paul Monks, Source Type: research
Clinical implications of concentration of alveolar nitric oxide in asthmatic and non-asthmatic
subacute cough
Asthma is an important cause of subacute cough. The concentration of alveolar nitric oxide (CANO) is
a sensitive inflammatory indicator in peripheral airways, and it has received much less attention
than the fraction of exhaled nitric oxide (FeNO 50 ). The main objective of this study was to
explore the correlation between CANO and clinical parameters in asthmatic and non-asthmatic subacute
cough, which might promote understanding of the clinical utility of CANO in these special patient
populations. 155 patients with subacute cough were included consecutively, of which 25 were
diagnosed as asthmatic. Data for demogra...
Source: Journal of Breath Research - November 25, 2021 Category: Respiratory Medicine Authors: Guan-Sheng Zeng, Hui Chen, Li-Chang Chen, Ling-Ling Wu and Hua-Peng Yu Source Type: research
Noninvasive real-time breath test for controlling hormonal background of the human body: detection
of serotonin and melatonin with quantum point-contact sensors
Significant progress in development of noninvasive diagnostic tools based on breath analysis can be
expected if one employs a real-time detection method based on finding a spectral breath profile
which would contain some energy characteristics of the analyzed gas mixture. Using the fundamental
energy parameters of a quantum system, it is possible to determine with a high accuracy its
quantitative and qualitative composition. Among the most efficient tools to measure energy
characteristics of quantum systems are sensors based on Yanson point contacts. This paper reports
the results of serotonin and melatonin detection...
Source: Journal of Breath Research - November 17, 2021 Category: Respiratory Medicine Authors: Lyudmila Kamarchuk, Alexander Pospelov, Dmytro Harbuz, Victor Belan, Yuliya Volkova, Anna Tkachenko and Gennadii Kamarchuk Source Type: research
Breath acetone concentration: too heterogeneous to constitute a diagnosis or prognosis biomarker in
heart failure? A systematic review and meta-analysis
Introduction . Exhaled breath acetone (ExA) has been investigated as a biomarker for heart failure
(HF). Yet, barriers to its use in the clinical field have not been identified. The aim of this
systematic review and meta-analysis was to assess the ExA heterogeneity and factors of variability
in healthy controls (HC), to identify its relations with HF diagnosis and prognostic factors and to
assess its diagnosis and prognosis accuracy in HF patients. Methods . A systematic search was
conducted in PUBMED and Web of Science database. All studies with HC and HF patients with a measured
ExA were included and studies provid...
Source: Journal of Breath Research - November 16, 2021 Category: Respiratory Medicine Authors: Fares Gouzi, Diba Ayache, Christophe H édon, Nicolas Molinari and Aurore Vicet Source Type: research
IABR Symposium 2021 meeting report: breath standardization, sampling, and testing in a time of
COVID-19
This report presents an overview of
the topics presented and various salient discussion points. (Source: Journal of Breath Research)
Source: Journal of Breath Research - November 8, 2021 Category: Respiratory Medicine Authors: Alexander J Schmidt, Dahlia Salman, Joachim Pleil, C L Paul Thomas and Cristina E Davis Source Type: research
Reply to comment on 'the comparison of two exhaled nitric oxide analyzers: NIOX VERO and
SUNVOU-CA2122'
Description unavailable (Source: Journal of Breath Research)
Source: Journal of Breath Research - November 1, 2021 Category: Respiratory Medicine Authors: Wei Lei, Fei Li, Xiao-miao Tang, Shuang Bian, Jia-jia Wang and Jian-an Huang Source Type: research
Comment on 'The comparison of two exhaled nitric oxide analyzers: NIOX VERO and SUNVOU-CA2122'
Description unavailable (Source: Journal of Breath Research)
Source: Journal of Breath Research - November 1, 2021 Category: Respiratory Medicine Authors: Alan K Kamada, Xinmei Jiang, Yang Wang and Bal Johal Source Type: research
Reply to comment on ‘the comparison of two exhaled nitric oxide analyzers: NIOX VERO and
SUNVOU-CA2122 ’
Description unavailable (Source: Journal of Breath Research)
Source: Journal of Breath Research - November 1, 2021 Category: Respiratory Medicine Authors: Wei Lei, Fei Li, Xiao-miao Tang, Shuang Bian, Jia-jia Wang and Jian-an Huang Source Type: research
Comment on ‘The comparison of two exhaled nitric oxide analyzers: NIOX VERO and SUNVOU-CA2122’
Description unavailable (Source: Journal of Breath Research)
Source: Journal of Breath Research - November 1, 2021 Category: Respiratory Medicine Authors: Alan K Kamada, Xinmei Jiang, Yang Wang and Bal Johal Source Type: research
COVID-19 screening using breath-borne volatile organic compounds
Rapid screening of COVID-19 is key to controlling the pandemic. However, current nucleic acid
amplification involves lengthy procedures in addition to the discomfort of taking throat/nasal
swabs. Here we describe potential breath-borne volatile organic compound (VOC) biomarkers together
with machine learning that can be used for point-of-care screening of COVID-19. Using a commercial
gas chromatograph-ion mobility spectrometer, higher levels of propanol were detected in the exhaled
breath of COVID-19 patients ( N = 74) and non-COVID-19 respiratory infections (RI) ( N = 30) than
those of non-COVID-19 controls (NC)/hea...
Source: Journal of Breath Research - October 21, 2021 Category: Respiratory Medicine Authors: Haoxuan Chen, Xiao Qi, Lu Zhang, Xinyue Li, Jianxin Ma, Chunyang Zhang, Huasong Feng and Maosheng Yao Source Type: research
Breath volatile organic compound analysis: an emerging method for gastric cancer detection
Gastric cancer is a common malignancy, being the fifth most frequently diagnosed cancer and the
fourth leading cause of cancer-related deaths worldwide. Diagnosis of gastric cancer at the early
stage is critical to effectively improve the survival rate. However, a substantial proportion of
patients with gastric cancer in the early stages lack specific symptoms or are asymptomatic.
Moreover, the imaging techniques currently used for gastric cancer screening, such as computed
tomography and barium examination, are usually radioactive and have low sensitivity and specificity.
Even though endoscopy has high accuracy for ...
Source: Journal of Breath Research - October 19, 2021 Category: Respiratory Medicine Authors: Jing Zhang, Yonghui Tian, Zewei Luo, Cheng Qian, Wenwen Li and Yixiang Duan Source Type: research
Prediction of potential passive exposure from commercial electronic nicotine delivery systems using
exhaled breath analysis and computational fluid dynamic techniques
Use of computational fluid dynamic (CFD) modeling to predict temporal and spatial constituent
exposure for non-electronic nicotine delivery systems (ENDS) users (passive exposure) provides a
more efficient methodology compared to conducting actual exposure studies. We conducted a clinical
study measuring exhaled breath concentrations of glycerin, propylene glycol, nicotine, benzoic acid,
formaldehyde, acetaldehyde, acrolein, menthol and carbon monoxide from use of eight different
commercial ENDS devices and a non-menthol and menthol cigarette. Because baseline adjusted levels of
other constituents were not consistent...
Source: Journal of Breath Research - October 4, 2021 Category: Respiratory Medicine Authors: Michael J Oldham, Patrick C Bailey, Nicolas Castro, Qiwei Lang, Armin Salehi and Ali A Rostami Source Type: research
COVID-19: the new cause of dyspnoea as a result of reduced lung and peripheral muscle performance
This study aimed to evaluate the cardiopulmonary function and impairment of exercise endurance in
patients with COVID-19 after 3 months of the second wave of the pandemic in Turkey. A total of 51
consecutive COVID-19 survivors, mostly healthcare providers, still working in the emergency room and
intensive care units of the hospital after the second wave of Covid 19 pandemia were included in
this study. Cardiopulmonary exercise stress test was performed. The median of the exercise time of
the COVID-19 survivors, was 10 (4.5 –13) minutes and the mean 6.8 ± 1.3 Mets was achieved. The VO 2
max of the COVID-19 survivor...
Source: Journal of Breath Research - October 3, 2021 Category: Respiratory Medicine Authors: Rezzan Deniz Acar, Ertan Sar ıbaş, Pınar Atagün Güney, Çağrı Kafkas, Derya Aydınlı, Erdal Taşçı and Mehmet Kaan Kırali Source Type: research
