Breath volatile organic compound analysis: an emerging method for gastric cancer detection
Gastric cancer is a common malignancy, being the fifth most frequently diagnosed cancer and the
fourth leading cause of cancer-related deaths worldwide. Diagnosis of gastric cancer at the early
stage is critical to effectively improve the survival rate. However, a substantial proportion of
patients with gastric cancer in the early stages lack specific symptoms or are asymptomatic.
Moreover, the imaging techniques currently used for gastric cancer screening, such as computed
tomography and barium examination, are usually radioactive and have low sensitivity and specificity.
Even though endoscopy has high accuracy for gastric cancer screening, its application is limited by
the invasiveness of the technique. Breath analysis is an economic, effective, easy to perform,
non-invasive detection method, and has no undesirable side effects on subjects. Extensive worldwide
research has been conducted on breath volatile organic compounds (VOCs), which reveals its prospect
as a potential met...
Source: Journal of Breath Research - Category: Respiratory Medicine Authors: Jing Zhang, Yonghui Tian, Zewei Luo, Cheng Qian, Wenwen Li and Yixiang Duan Source Type: research
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