An overview of advanced biocompatible and biomimetic materials for creation of replacement structures in the musculoskeletal systems: focusing on cartilage tissue engineering
Tissue engineering, as an interdisciplinary approach, is seeking to create tissues with optimal performance for clinical applications. Various factors, including cells, biomaterials, cell or tissue culture con... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 13, 2019 Category: Biotechnology Authors: Azizeh Rahmani Del Bakhshayesh, Nahideh Asadi, Alireza Alihemmati, Hamid Tayefi Nasrabadi, Azadeh Montaseri, Soodabeh Davaran, Sepideh Saghati, Abolfazl Akbarzadeh and Ali Abedelahi Tags: Review Source Type: research
Effects of endogenous inflammation signals elicited by nerve growth factor, interferon- γ, and interleukin-4 on peripheral nerve regeneration
Large gap healing is a difficult issue in the recovery of peripheral nerve injury. The present study provides in vivo trials of silicone rubber chambers filled with collagen containing IFN- γ or IL-4 to bridge ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 13, 2019 Category: Biotechnology Authors: Chien-Fu Liao, Chung-Chia Chen, Yu-Wen Lu, Chun-Hsu Yao, Jia-Horng Lin, Tzong-Der Way, Tse-Yen Yang and Yueh-Sheng Chen Tags: Research Source Type: research
Electrospun nanofibers for the fabrication of engineered vascular grafts
Attention has recently increased in the application of electrospun fibers because of their putative capability to create nanoscale platforms toward tissue engineering. To some extent, electrospun fibers are ap... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 11, 2019 Category: Biotechnology Authors: Sonia Fathi Karkan, Soodabeh Davaran, Reza Rahbarghazi, Roya Salehi and Abolfazl Akbarzadeh Tags: Review Source Type: research
Correction to: Computational analysis of viable parameter regions in models of synthetic biological systems
The original version of this article [1] unfortunately included a typographical error to author Žiga Pušnik’s name. (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 11, 2019 Category: Biotechnology Authors: Žiga Pušnik, Miha Mraz, Nikolaj Zimic and Miha Moškon Tags: Correction Source Type: research
Evaluation of human primary intestinal monolayers for drug metabolizing capabilities
The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II drug metabolizing enzymes (DMEs). The enterocytes are s... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 4, 2019 Category: Biotechnology Authors: Jennifer E. Speer, Yuli Wang, John K. Fallon, Philip C. Smith and Nancy L. Allbritton Tags: Research Source Type: research
Unique N-glycosylation of a recombinant exo-inulinase from Kluyveromyces cicerisporus and its effect on enzymatic activity and thermostability
Inulinase can hydrolyze polyfructan into high-fructose syrups and fructoligosaccharides, which are widely used in food, the medical industry and the biorefinery of Jerusalem artichoke. In the present study, a rec... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 29, 2019 Category: Biotechnology Authors: Junyan Ma, Qian Li, Haidong Tan, Hao Jiang, Kuikui Li, Lihua Zhang, Quan Shi and Heng Yin Tags: Research Source Type: research
3D-tips: user-friendly mesh barrier pipette tips for 3D-spheroid culture
Three dimensional (3D) cell cultures have been an area of increasing interest and relevance across several research fields including drug discovery, developmental biology and stem cell-based therapies. However... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 28, 2019 Category: Biotechnology Authors: Mo Chen, Marie-Laure Vial and James A. St John Tags: Research Source Type: research
A novel egg-shell membrane based hybrid nanofibrous scaffold for cutaneous tissue engineering
The main issue in cutaneous regeneration is to develop engineered scaffolds based on natural extracellular matrix to promote dynamics of skin progenitor cells and accelerate differentiation into mature keratin... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 26, 2019 Category: Biotechnology Authors: Leila Mohammadzadeh, Reza Rahbarghazi, Roya Salehi and Mehrdad Mahkam Tags: Research Source Type: research
Process development for pandemic influenza VLP vaccine production using a baculovirus expression system
Influenza viruses cause hundreds of thousands of respiratory diseases worldwide each year, and vaccination is considered the most effective approach for preventing influenza annual epidemics or pandemics. Sinc... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 23, 2019 Category: Biotechnology Authors: Chia-Chun Lai, Yu-Chieh Cheng, Pin-Wen Chen, Ting-Hui Lin, Tsai-Teng Tzeng, Chia-Chun Lu, Min-Shi Lee and Alan Yung-Chih Hu Tags: Research Source Type: research
Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model
The baculovirus (BV) Autographa californica multiple nuclear polyhedrosis virus has been used in numerous protein expression systems because of its ability to infect insect cells and serves as a useful vaccinatio... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 22, 2019 Category: Biotechnology Authors: Keigo Kondou, Tomoyuki Suzuki, Myint Oo Chang and Hiroshi Takaku Tags: Research Source Type: research
De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions
The promise of biopharmaceuticals comprising one or more binding domains motivates the development of novel methods for de novo isolation and affinity maturation of virion-binding domains. Identifying avenues ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 16, 2019 Category: Biotechnology Authors: Pete Heinzelman, Alyssa Low, Rudo Simeon, Gus A. Wright and Zhilei Chen Tags: Research Source Type: research
Computational analysis of viable parameter regions in models of synthetic biological systems
Gene regulatory networks with different topological and/or dynamical properties might exhibit similar behavior. System that is less perceptive for the perturbations of its internal and external factors should ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - September 18, 2019 Category: Biotechnology Authors: žiga Pušnik, Miha Mraz, Nikolaj Zimic and Miha Moškon Tags: Methodology Source Type: research
Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel ™ bioreactors
Since their inception, human induced pluripotent stem cells (hiPSCs) have held much promise for pharmacological applications and cell-based therapies. However, their potential can only be realised if large num... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - September 14, 2019 Category: Biotechnology Authors: Diogo E. S. Nogueira, Carlos A. V. Rodrigues, Marta S. Carvalho, Cl áudia C. Miranda, Yas Hashimura, Sunghoon Jung, Brian Lee and Joaquim M. S. Cabral Tags: Research Source Type: research
Jamming state transition and collective cell migration
Jamming state transition has been used in literature to describe migrating-to-resting cell state transition during collective cell migration without proper rheological confirmation. Yield stress often has been... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - September 5, 2019 Category: Biotechnology Authors: Ivana Pajic-Lijakovic and Milan Milivojevic Tags: Research Source Type: research
Marimo machines: oscillators, biosensors and actuators
The green algae balls (Aegagropila linnaei), known as Marimo, are large spherical colonies of live photosynthetic filaments, formed by rolling water currents in freshwater lakes. Photosynthesis therein produces g... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - September 3, 2019 Category: Biotechnology Authors: Neil Phillips, Thomas C. Draper, Richard Mayne and Andrew Adamatzky Tags: Research Source Type: research
