Application of fibrin-based hydrogels for nerve protection and regeneration after spinal cord injury
Traffic accidents, falls, and many other events may cause traumatic spinal cord injuries (SCIs), resulting in nerve cells and extracellular matrix loss in the spinal cord, along with blood loss, inflammation, ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - August 3, 2020 Category: Biotechnology Authors: Ziyuan Yu, Hongru Li, Peng Xia, Weijian Kong, Yuxin Chang, Chuan Fu, Kai Wang, Xiaoyu Yang and Zhiping Qi Tags: Review Source Type: research
Development of a novel heterologous β-lactam-specific whole-cell biosensor in Bacillus subtilis
Whole-cell biosensors are a powerful and easy-to-use screening tool for the fast and sensitive detection of chemical compounds, such as antibiotics. β-Lactams still represent one of the most important antibiot... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - July 31, 2020 Category: Biotechnology Authors: Nina Lautenschl äger, Philipp F. Popp and Thorsten Mascher Tags: Research Source Type: research
Paper-based in vitro tissue chip for delivering programmed mechanical stimuli of local compression and shear flow
Mechanical stimuli play important roles on the growth, development, and behavior of tissue. A simple and novel paper-based in vitro tissue chip was developed that can deliver two types of mechanical stimuli —lo... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - July 28, 2020 Category: Biotechnology Authors: Kattika Kaarj, Marianne Madias, Patarajarin Akarapipad, Soohee Cho and Jeong-Yeol Yoon Tags: Methodology Source Type: research
Reflections: 25th anniversary of the Institute of Biological Engineering (IBE)
(Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - July 9, 2020 Category: Biotechnology Authors: Brahm P. Verma Tags: Editorial Source Type: research
Novel 3D embryo implantation model within macroporous alginate scaffolds
Implantation failure remains an unsolved obstacle in reproductive medicine. Previous studies have indicated that estrogen responsiveness, specifically by estrogen receptor alpha (ER α), is crucial for proper im... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - June 30, 2020 Category: Biotechnology Authors: Dganit Stern-Tal, Hanna Achache, Liora Jacobs Catane, Reuven Reich and Tali Tavor Re ’em Tags: Research Source Type: research
Correction to: Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting
An amendment to this paper has been published and can be accessed via the original article. (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - June 12, 2020 Category: Biotechnology Authors: Farhad Abasalizadeh, Sevil Vaghefi Moghaddam, Effat Alizadeh, Elahe Akbari, Elmira Kashani, Seyyed Mohammad Bagher Fazljou, Mohammadali Torbati and Abolfazl Akbarzadeh Tags: Correction Source Type: research
High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells
Human mesenchymal stem cells (hMSCs) are intensely researched for applications in cell therapeutics due to their unique properties, however, intrinsic therapeutic properties of hMSCs could be enhanced by genet... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - May 19, 2020 Category: Biotechnology Authors: Tyler Kozisek, Andrew Hamann, Albert Nguyen, Michael Miller, Sarah Plautz and Angela K. Pannier Tags: Research Source Type: research
Formaldehyde formation in the glycine cleavage system and its use for an aldolase-based biosynthesis of 1,3-prodanediol
Glycine cleavage system (GCS) occupies a key position in one-carbon (C1) metabolic pathway and receives great attention for the use of C1 carbons like formate and CO2 via synthetic biology. In this work, we demon... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - May 14, 2020 Category: Biotechnology Authors: Yingying Xu, Hao Meng, Jie Ren and An-Ping Zeng Tags: Research Source Type: research
Advances in the application of gold nanoparticles in bone tissue engineering
The materials used in bone tissue engineering (BTE) have been advancing with each passing day. With the continuous development of nanomedicine, gold nanoparticles (GNPs), which are easy to be synthesized and f... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - May 6, 2020 Category: Biotechnology Authors: Hongru Li, Su Pan, Peng Xia, Yuxin Chang, Chuan Fu, Weijian Kong, Ziyuan Yu, Kai Wang, Xiaoyu Yang and Zhiping Qi Tags: Review Source Type: research
Acute mechanical stress in primary porcine RPE cells induces angiogenic factor expression and in vitro angiogenesis
Choroidal neovascularization (CNV) is a major cause of blindness in patients with age-related macular degeneration. CNV is characterized by new blood vessel growth and subretinal fluid accumulation, which resu... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - April 25, 2020 Category: Biotechnology Authors: Farhad Farjood, Amir Ahmadpour, Sassan Ostvar and Elizabeth Vargis Tags: Research Source Type: research
Probing the operability regime of an engineered ribocomputing unit in terms of dynamic range maintenance with extracellular changes and time
Synthetic biology aims at engineering gene regulatory circuits to end with cells (re)programmed on purpose to implement novel functions or discover natural behaviors. However, one overlooked question is whethe... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 26, 2020 Category: Biotechnology Authors: Roser Montagud-Mart ínez, Jordi Ventura, Rafael Ballesteros-Garrido, Arantxa Rosado and Guillermo Rodrigo Tags: Research Source Type: research
Tubular bile duct structure mimicking bile duct morphogenesis for prospective in vitro liver metabolite recovery
Liver metabolites are used to diagnose disease and examine drugs in clinical pharmacokinetics. Therefore, development of an in vitro assay system that reproduces liver metabolite recovery would provide importa... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 19, 2020 Category: Biotechnology Authors: Astia Rizki-Safitri, Marie Shinohara, Minoru Tanaka and Yasuyuki Sakai Tags: Research Source Type: research
The head and neck cancer (HN-5) cell line properties extraction by AFM
This work incorporates experimental methods based on Atomic Force Microscopy (AFM) in order to extract the physical and mechanical characteristics of the head and neck cancer (HN-5) cell line such as cell topo... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 18, 2020 Category: Biotechnology Authors: M. H. Korayem, K. Heidary and Z. Rastegar Tags: Research Source Type: research
The long-term residual effects of low-magnitude mechanical stimulation therapy on skeletal health
The objective of this research was to investigate the long-term residual effects of LMMS on bone health. 10-week old female mice were gi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 14, 2020 Category: Biotechnology Authors: Kyle A. Bodnyk, Kyle S. Kuchynsky, Megan Balgemann, Brooke Stephens and Richard T. Hart Tags: Research Source Type: research
Alginate-based hydrogels as drug delivery vehicles in cancer treatment and their applications in wound dressing and 3D bioprinting
Hydrogels are a three-dimensional and crosslinked network of hydrophilic polymers. They can absorb a large amount of water or biological fluids, which leads to their swelling while maintaining their 3D structu... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 13, 2020 Category: Biotechnology Authors: Farhad Abasalizadeh, Sevil Vaghefi Moghaddam, Effat Alizadeh, Elahe akbari, Elmira Kashani, Seyyed Mohammad Bagher Fazljou, Mohammadali Torbati and Abolfazl Akbarzadeh Tags: Review Source Type: research
