Proteomic analysis of decellularized mice liver and kidney extracellular matrices
The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality.... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 22, 2024 Category: Biotechnology Authors: Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher and Benjamin St Tags: Research Source Type: research
Chitosan as a promising materials for the construction of nanocarriers for diabetic retinopathy: an updated review
Diabetic retinopathy (DR) is a condition that causes swelling of the blood vessels of the retina and leaks blood and fluids. It is the most severe form of diabetic eye disease. It causes vision loss in its adv... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 22, 2024 Category: Biotechnology Authors: Yan Lv, Chenglei Zhai, Gang Sun and Yangfang He Tags: Review Source Type: research
Advanced biomanufacturing and evaluation of adeno-associated virus
This study aimed to establish a novel biomanufacturing process to achi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 15, 2024 Category: Biotechnology Authors: Kai Chen, Seulhee Kim, Siying Yang, Tanvi Varadkar, Zhuoxin Zora Zhou, Jiashuai Zhang, Lufang Zhou and Xiaoguang Margaret Liu Tags: Research Source Type: research
The progressive trend of modeling and drug screening systems of breast cancer bone metastasis
Bone metastasis is considered as a considerable challenge for breast cancer patients. Various in vitro and in vivo models have been developed to examine this occurrence. In vitro models are employed to simulat... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 5, 2024 Category: Biotechnology Authors: Hanieh Kolahi Azar, Maliheh Gharibshahian, Mohammadreza Rostami, Vahid Mansouri, Leila Sabouri, Nima Beheshtizadeh and Nima Rezaei Tags: Review Source Type: research
Enhancing osteogenic differentiation of dental pulp stem cells through rosuvastatin loaded niosomes optimized by Box-Behnken design and modified by hyaluronan: a novel strategy for improved efficiency
Bone tissue engineering necessitates a stem cell source capable of osteoblast differentiation and mineralized matrix production. Dental pulp stem cells (DPSCs), a subtype of mesenchymal stem cells from human t... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 26, 2024 Category: Biotechnology Authors: Zaynab Sadeghi Ghadi, Amin Asadi, Younes Pilehvar, Mozhgan Abasi and Pedram Ebrahimnejad Tags: Research Source Type: research
Optimize the parameters for the synthesis by the ionic gelation technique, purification, and freeze-drying of chitosan-sodium tripolyphosphate nanoparticles for biomedical purposes
Polymeric nanoparticles can be used for wound closure and therapeutic compound delivery, among other biomedical applications. Although there are several nanoparticle obtention methods, it is crucial to know th... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 25, 2024 Category: Biotechnology Authors: Stephany Celeste Guti érrez-Ruíz, Hernán Cortes, Maykel González-Torres, Zainab M. Almarhoon, Eda Sönmez Gürer, Javad Sharifi-Rad and Gerardo Leyva-Gómez Tags: Research Source Type: research
Exploring the impact of taurine on the biochemical properties of urate oxidase: response surface methodology and molecular dynamics simulation
This paper investigates the impact of taurine as an additive on the structural and functional stability of urate oxidase. First, the effect of the processing parameters for the stabilization of Urate Oxidase (... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 22, 2024 Category: Biotechnology Authors: Parisa Shahmoradipour, Maryam Zaboli and Masoud Torkzadeh-Mahani Tags: Research Source Type: research
Poly-3-hydroxybutyrate-co-3-hydroxyvalerate(PHBV)-Polyethylene glycol 20k(PEG20k) as a promising delivery system for PT2399 in the treatment of disc degeneration
Disc degeneration often leads to a highly prevalent symptom known as low back pain. Healthy nucleus pulposus tissue exhibited a hypoxic environment devoid of blood vessels, while degenerated nucleus pulposus e... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 22, 2024 Category: Biotechnology Authors: Zhencong Li, Weilin Zhang, Shengbang Huang, Zhiwen Dai, Jinguo Liang, Qiulan Qiu, Siyuan Chen, Weixiong Guo, Zhongwei Wang and Jinsong Wei Tags: Research Source Type: research
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
This study aimed to develop no... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 16, 2024 Category: Biotechnology Authors: Wenxuan Wang, Tingting Yang, Sihui Chen, Liying Liang, Yingxin Wang, Yin Ding, Wei Xiong, Xiuhong Ye, Yonglong Guo, Shuhao Shen, Hang Chen and Jiansu Chen Tags: Research Source Type: research
Stable, neuron-specific gene expression in the mouse brain
Gene delivery to, and expression in, the mouse brain is important for understanding gene functions in brain development and disease, or testing gene therapies. Here, we describe an approach to express a transg... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 16, 2024 Category: Biotechnology Authors: Osama Ahmed, Kingsley M. Ekumi, Francesco V. Nardi, Gulimiheranmu Maisumu, Khaled Moussawi, Eric D. Lazartigues, Bo Liang and Abraam M. Yakoub Tags: Methodology Source Type: research
An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors
Viral vectors are attractive gene delivery vehicles because of their broad tropism, high transduction efficiency, and durable expression. With no risk of integration into the host genome, the vectors developed... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 16, 2024 Category: Biotechnology Authors: Takumi Kishimoto, Ken Nishimura, Kana Morishita, Aya Fukuda, Yusaku Miyamae, Yutaro Kumagai, Kimio Sumaru, Mahito Nakanishi, Koji Hisatake and Masayuki Sano Tags: Research Source Type: research
Kinematic movement and balance parameter analysis in neurological gait disorders
Neurological gait disorders are mainly classified based on clinical observation, and therefore difficult to objectify or quantify. Movement analysis systems provide objective parameters, which may increase dia... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 15, 2024 Category: Biotechnology Authors: Chuh-Hyoun Na, Hannah Lena Siebers, Julia Reim, J örg Eschweiler, Frank Hildebrand, Hans Clusmann and Marcel Betsch Tags: Research Source Type: research
Mussel-inspired electroactive, antibacterial and antioxidative composite membranes with incorporation of gold nanoparticles and antibacterial peptides for enhancing skin wound healing
Large skin wounds are one of the most important health problems in the world. Skin wound repair and tissue regeneration are complex processes involving many physiological signals, and effective wound healing r... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 11, 2024 Category: Biotechnology Authors: Yongkang Dong, Zheng Wang, Jiapeng Wang, Xuedi Sun, Xiaoyu Yang and Guomin Liu Tags: Research Source Type: research
Optimization of a recombinant BlaR-CTD protein formulation using the response surface methodology
The sequence of a carboxy-terminal of the β-lactam sensor-transducer protein (BlaR-CTD) from Bacillus licheniformis ATCC14580 was extracted from US7745193B2 patent and expressed in E. coli using pColdI vector ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 11, 2024 Category: Biotechnology Authors: Mohadeseh Haji Abdolvahab, Mojdeh Safari, Farkhonde Hasannejad, Nika Asefi, Alireza Salimi and Mahboobeh Nazari Tags: Research Source Type: research
An ovalbumin fusion strategy to increase recombinant protein secretion in chicken eggs
Maternal secretion of recombinant proteins into chicken eggs may provide a viable approach for pharmaceutical production but remains limited by poor secretion efficiency through the membrane of oviduct cells, ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 11, 2024 Category: Biotechnology Authors: Long Xie, Zhenwen Huang, Meiyu Lan, Yaqi Cao, Lingling Sun, Lang Zhang, Erwei Zuo and Yangqing Lu Tags: Research Source Type: research
