Potential application of hydrogel to the diagnosis and treatment of multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. This disorder may cause progressive and permanent impairment, placing significant physical and psychological strain on ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - April 8, 2022 Category: Biotechnology Authors: Haochuan Liu, Bing Chen and Qingsan Zhu Tags: Review Source Type: research

Tissue engineering of the gastrointestinal tract: the historic path to translation
The gastrointestinal (GI) tract is imperative for multiple functions including digestion, nutrient absorption, and timely waste disposal. The central feature of the gut is peristalsis, intestinal motility, whi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - April 4, 2022 Category: Biotechnology Authors: Claudia A. Collier, Christian Mendiondo and Shreya Raghavan Tags: Review Source Type: research

Correction to: Exosomes derived from microRNA-138-5poverexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2
(Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 31, 2022 Category: Biotechnology Authors: Yiming Deng, Duanduan Chen, Feng Gao, Hong Lv, Guojun Zhang, Xuan Sun, Lian Liu, Dapeng Mo, Ning Ma, Ligang Song, Xiaochuan Huo, Tianyi Yan, Jingbo Zhang and Zhongrong Miao Tags: Correction Source Type: research

Review: biological engineering for nature-based climate solutions
Nature-based Climate Solutions are landscape stewardship techniques to reduce greenhouse gas emissions and increase soil or biomass carbon sequestration. These mitigation approaches to climate change present a... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 29, 2022 Category: Biotechnology Authors: Benjamin R. K. Runkle Tags: Review Source Type: research

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds
Certain polymeric materials such as polyurethanes (PUs) are the most prevalent class of used biomaterials in regenerative medicine and have been widely explored as vascular substitutes in several animal models... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 24, 2022 Category: Biotechnology Authors: Sonia Fathi-Karkan, Behnaz Banimohamad-Shotorbani, Sepideh Saghati, Reza Rahbarghazi and Soodabeh Davaran Tags: Review Source Type: research

Mechanical overload decreases tenogenic differentiation compared to physiological load in bioartificial tendons
Tenocytes as specialised fibroblasts and inherent cells of tendons require mechanical load for their homeostasis. However, how mechanical overload compared to physiological load impacts on the tenogenic differ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 3, 2022 Category: Biotechnology Authors: Stefan Pentzold and Britt Wildemann Tags: Research Source Type: research

Structural insights into inhibition of PRRSV Nsp4 revealed by structure-based virtual screening, molecular dynamics, and MM-PBSA studies
Porcine reproductive and respiratory syndrome respiratory sickness in weaned and growing pigs, as well as sow reproductive failure, and its infection is regarded as one of the most serious swine illnesses worl... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 22, 2022 Category: Biotechnology Authors: Rajesh Kumar Pathak, Young-Jun Seo and Jun-Mo Kim Tags: Research Source Type: research

Application of decellularized bone matrix as a bioscaffold in bone tissue engineering
Autologous bone grafts are commonly used as the gold standard to repair and regenerate diseased bones. However, they are strongly associated with postoperative complications, especially at the donor site, and ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 5, 2022 Category: Biotechnology Authors: Halimeh Amirazad, Mehdi Dadashpour and Nosratollah Zarghami Tags: Review Source Type: research

Knockdown of NCK1-AS1 inhibits the development of atherosclerosis by targeting miR-1197/COX10 axis
Although long non-coding RNA (lncRNA) NCK1-AS1 plays important roles in human cancer, its function in atherosclerosis (AS) remains unclear. (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 5, 2022 Category: Biotechnology Authors: Bin Zhang, Juncheng Wang, Lei Du, Lufei Shao, Yourui Zou, Haibo Liu and Jinfang Liu Tags: Research Source Type: research

Marimo actuated rover systems
The potential to directly harness photosynthesis to make actuators, biosensors and bioprocessors has been previously demonstrated in the literature. Herein, this capability has been expanded to more advanced s... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 5, 2022 Category: Biotechnology Authors: Neil Phillips, Thomas C. Draper, Richard Mayne, Darren M. Reynolds and Andrew Adamatzky Tags: Research Source Type: research

Fetal ischemia monitoring with in vivo implanted electrochemical multiparametric microsensors
Under intrauterine growth restriction (IUGR), abnormal attainment of the nutrients and oxygen by the fetus restricts the normal evolution of the prenatal causing in many cases high morbidity being one of the t... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - December 20, 2021 Category: Biotechnology Authors: Samuel Dulay, Lourdes Rivas, Laura Pla, Sergio Berd ún, Elisenda Eixarch, Eduard Gratacós, Miriam Illa, Mònica Mir and Josep Samitier Tags: Research Source Type: research

The effect of surface morphology on endothelial and smooth muscle cells growth on blow-spun fibrous scaffolds
This study aimed to analyze the growth of two types of blood vessel building cells: endothelial cells (ECs) and smooth muscle cells (SMCs) on surfaces with different morphology. Two types of materials, differi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - December 19, 2021 Category: Biotechnology Authors: Iwona Łopianiak, Michał Wojasiński, Aleksandra Kuźmińska, Paulina Trzaskowska and Beata A. Butruk-Raszeja Tags: Research Source Type: research

Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
Since autologous veins are unavailable when needed in more than 20% of cases in vascular surgery, the production of personalized biological vascular grafts for implantation has become crucial. Surface modifica... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - November 24, 2021 Category: Biotechnology Authors: Eriselda Keshi, Peter Tang, Marie Weinhart, Hannah Everwien, Simon Moosburner, Nicolai Seiffert, Michael Lommel, Ulrich Kertzscher, Brigitta Globke, Anja Reutzel-Selke, Benjamin Str ücker, Johann Pratschke, Igor Maximillian Sauer, Nils Haep and Karl Herb Tags: Research Source Type: research

Assessment of the efficiency of synergistic photocatalysis on penicillin G biodegradation by whole cell Paracoccus sp
The Paracoccus sp. strain isolated from sludge was identified and evaluated for catalytic activity in the degradation of penicillin G. (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 27, 2021 Category: Biotechnology Authors: Peng Wang, Shouxin Liu, Xiaochun Wang, Qinqin Cong and Jialin Lu Tags: Research Source Type: research

AZD2014, a dual mTOR inhibitor, attenuates cardiac hypertrophy in vitro and in vivo
Cardiac hypertrophy is one of the most common genetic heart disorders and considered a risk factor for cardiac morbidity and mortality. The mammalian target of rapamycin (mTOR) pathway plays a key regulatory f... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - October 21, 2021 Category: Biotechnology Authors: Byung-Hyun Cha, Minjin Jung, Angela S. Kim, Victoria C. Lepak, Brett A. Colson, David A. Bull and Youngwook Won Tags: Research Source Type: research