An in vitro culture platform for studying the effect of collective cell migration on spatial self-organization within induced pluripotent stem cell colonies
Human induced pluripotent stem cells (hiPSCs) provide an in vitro system to identify the impact of cell behavior on the earliest stages of cell fate specification during human development. Here, we developed a... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 30, 2023 Category: Biotechnology Authors: Mee-Hae Kim, Masaki Kuroda, Ding Ke, Naruchit Thanuthanakhun and Masahiro Kino-oka Tags: Research Source Type: research

Early introduction of 3D modeling modules promotes the development of simulation skills in downstream biomedical engineering curricula
Recent advancements in additive manufacturing have made 3D design a desirable skill in combating the historically slow development of biomedical products. Due to the broad applicability of additive manufactur... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 30, 2023 Category: Biotechnology Authors: Mary S. Jia, Raj R. Rao and Mostafa Elsaadany Tags: Research Source Type: research

Unravelling the mechanotransduction pathways in Alzheimer ’s disease
Alzheimer ’s disease (AD) represents one of the most common and debilitating neurodegenerative disorders. By the end of 2040, AD patients might reach 11.2 million in the USA, around 70% higher than 2022, with s... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 28, 2023 Category: Biotechnology Authors: Francesca Donnaloja, Emma Limonta, Christian Mancosu, Francesco Morandi, Lucia Boeri, Diego Albani and Manuela Teresa Raimondi Tags: Review Source Type: research

Melatonin and endothelial cell-loaded alginate-fibrin hydrogel promoted angiogenesis in rat cryopreserved/thawed ovaries transplanted to the heterotopic sites
Ischemic niche can promote follicular atresia following the transplantation of cryopreserved/thawed ovaries to the heterotopic sites. Thus, the promotion of blood supply is an effective strategy to inhibit/red... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 28, 2023 Category: Biotechnology Authors: Melika Izadpanah, Azizeh Rahmani Del Bakhshayesh, Zahra Bahroudi, Abbas Majdi Seghinsara, Rahim Beheshti, Mahdi Mahdipour, Mahsa Rezaii Zarnaghi, Parisa Hassanpour, Narges Mardi, Reza Rahbarghazi and Ali Abedelahi Tags: Research Source Type: research

Recent advances in modified poly (lactic acid) as tissue engineering materials
As an emerging science, tissue engineering and regenerative medicine focus on developing materials to replace, restore or improve organs or tissues and enhancing the cellular capacity to proliferate, migrate a... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 20, 2023 Category: Biotechnology Authors: Samanta Casta ñeda-Rodríguez, Maykel González-Torres, Rosa María Ribas-Aparicio, María Luisa Del Prado‑Audelo, Gerardo Leyva‑Gómez, Eda Sönmez Gürer and Javad Sharifi‑Rad Tags: Review Source Type: research

Multilayered blow-spun vascular prostheses with luminal surfaces in Nano/Micro range: the influence on endothelial cell and platelet adhesion
In this study, two types of polyurethane-based cylindrical multilayered grafts with internal diameters  ≤ 6 mm were produced by the solution blow spinning (SBS) method. The main aim was to create layered-wall p... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 13, 2023 Category: Biotechnology Authors: Iwona Łopianiak, Wiktoria Rzempołuch, Mehtap Civelek, Iwona Cicha, Tomasz Ciach and Beata A. Butruk-Raszeja Tags: Research Source Type: research

Customized biofilm device for antibiofilm and antibacterial screening of newly developed nanostructured silver and zinc coatings
Bacterial colonisation on implantable device surfaces is estimated to cause more than half of healthcare-associated infections. The application of inorganic coatings onto implantable devices limits/prevents mi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 6, 2023 Category: Biotechnology Authors: Daniele Ghezzi, Marco Boi, Enrico Sassoni, Francesco Valle, Elena Giusto, Elisa Boanini, Nicola Baldini, Martina Cappelletti and Gabriela Graziani Tags: Research Source Type: research

Antioxidant activities in relation to the transport of heavy metals from the soil to different parts of Betula pendula (Roth.)
Birch is a tree with a common occurrence in the environment and its organs are used in the form of herbal material. An important aspect of this study is birch pollen, which is a problem for allergy sufferers, ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 6, 2023 Category: Biotechnology Authors: Iwona Makuch-Pietra ś, Dorota Grabek-Lejko, Anna Górka and Idalia Kasprzyk Tags: Research Source Type: research

The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition
Epithelial-mesenchymal plasticity (EMP) involves bidirectional transitions between epithelial, mesenchymal and multiple intermediary hybrid epithelial/mesenchymal phenotypes. While the process of epithelial-me... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 2, 2023 Category: Biotechnology Authors: Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Prakruthi Manjunatha, Shaurya Goyal, Vignesh A Kasiviswanathan, Yeshwanth Mahesh, Soundharya Ramu, Isabelle McMullen, Jason A. Somarelli and Mohit Kumar Jolly Tags: Research Source Type: research

Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation
Calcium oxalate (CaOx) stone disease is found worldwide. To explore the role of exosomes as a mediator of intercellular crosstalk during CaOx stone formation, we conducted this study, which may provide a new i... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 28, 2023 Category: Biotechnology Authors: Yuanyuan Yang, Senyuan Hong, Qing Wang, Shaogang Wang and Yang Xun Tags: Research Source Type: research

Dynamic interaction of injected liquid jet with skin layer interfaces revealed by microsecond imaging of optically cleared ex vivo skin tissue model
Needle-free jet injection (NFJI) systems enable a controlled and targeted delivery of drugs into skin tissue. However, a scarce understanding of their underlying mechanisms has been a major deterrent to the de... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 27, 2023 Category: Biotechnology Authors: Abdul Mohizin, Jakir Hossain Imran, Kee Sung Lee and Jung Kyung Kim Tags: Research Source Type: research

Synergistic improvement of cinnamylamine production by metabolic regulation
Aromatic primary amines (APAs) are key intermediates in the chemical industry with numerous applications. Efficient and mild biocatalytic synthesis is an excellent complement to traditional chemical synthesis.... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 23, 2023 Category: Biotechnology Authors: Shan Yuan, Chao Xu, Miaomiao Jin, Mo Xian and Wei Liu Tags: Research Source Type: research

Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regene... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 16, 2023 Category: Biotechnology Authors: Xinyue Chen, Wenlu Yu, Jing Zhang, Xiao Fan, Xiao Liu, Qi Liu, Su Pan, Richard A. F. Dixon, Pengyang Li, Peng Yu and Ao Shi Tags: Review Source Type: research

Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha
Non-invasive online fluorescence monitoring in high-throughput microbioreactors is a well-established method to accelerate early-stage bioprocess development. Recently, single-wavelength fluorescence monitorin... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 13, 2023 Category: Biotechnology Authors: Christoph Berg, Laura Herbst, Lisa Gremm, Nina Ihling, Olivier Paquet-Durand, Bernd Hitzmann and Jochen B üchs Tags: Research Source Type: research

Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration
Chronic disease can cause tissue and organ damage constituting the largest obstacle to therapy which, in turn, reduces patients ’ quality-adjusted life-year. Degenerative diseases such as osteoporosis, Alzheime... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 9, 2023 Category: Biotechnology Authors: Andang Miatmoko, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Syarifah Sutra Dewangga, Kevin Ksatria Handoko, Purwati, Ram Kumar Sahu and Dewi Melani Hariyadi Tags: Review Source Type: research