Antioxidant activities in relation to the transport of heavy metals from the soil to different parts of Betula pendula (Roth.)
Birch is a tree with a common occurrence in the environment and its organs are used in the form of herbal material. An important aspect of this study is birch pollen, which is a problem for allergy sufferers, ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 6, 2023 Category: Biotechnology Authors: Iwona Makuch-Pietra ś, Dorota Grabek-Lejko, Anna Górka and Idalia Kasprzyk Tags: Research Source Type: research

The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition
Epithelial-mesenchymal plasticity (EMP) involves bidirectional transitions between epithelial, mesenchymal and multiple intermediary hybrid epithelial/mesenchymal phenotypes. While the process of epithelial-me... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - March 2, 2023 Category: Biotechnology Authors: Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Prakruthi Manjunatha, Shaurya Goyal, Vignesh A Kasiviswanathan, Yeshwanth Mahesh, Soundharya Ramu, Isabelle McMullen, Jason A. Somarelli and Mohit Kumar Jolly Tags: Research Source Type: research

Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formation
Calcium oxalate (CaOx) stone disease is found worldwide. To explore the role of exosomes as a mediator of intercellular crosstalk during CaOx stone formation, we conducted this study, which may provide a new i... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 28, 2023 Category: Biotechnology Authors: Yuanyuan Yang, Senyuan Hong, Qing Wang, Shaogang Wang and Yang Xun Tags: Research Source Type: research

Dynamic interaction of injected liquid jet with skin layer interfaces revealed by microsecond imaging of optically cleared ex vivo skin tissue model
Needle-free jet injection (NFJI) systems enable a controlled and targeted delivery of drugs into skin tissue. However, a scarce understanding of their underlying mechanisms has been a major deterrent to the de... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 27, 2023 Category: Biotechnology Authors: Abdul Mohizin, Jakir Hossain Imran, Kee Sung Lee and Jung Kyung Kim Tags: Research Source Type: research

Synergistic improvement of cinnamylamine production by metabolic regulation
Aromatic primary amines (APAs) are key intermediates in the chemical industry with numerous applications. Efficient and mild biocatalytic synthesis is an excellent complement to traditional chemical synthesis.... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 23, 2023 Category: Biotechnology Authors: Shan Yuan, Chao Xu, Miaomiao Jin, Mo Xian and Wei Liu Tags: Research Source Type: research

Therapeutic angiogenesis and tissue revascularization in ischemic vascular disease
Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regene... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 16, 2023 Category: Biotechnology Authors: Xinyue Chen, Wenlu Yu, Jing Zhang, Xiao Fan, Xiao Liu, Qi Liu, Su Pan, Richard A. F. Dixon, Pengyang Li, Peng Yu and Ao Shi Tags: Review Source Type: research

Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha
Non-invasive online fluorescence monitoring in high-throughput microbioreactors is a well-established method to accelerate early-stage bioprocess development. Recently, single-wavelength fluorescence monitorin... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 13, 2023 Category: Biotechnology Authors: Christoph Berg, Laura Herbst, Lisa Gremm, Nina Ihling, Olivier Paquet-Durand, Bernd Hitzmann and Jochen B üchs Tags: Research Source Type: research

Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration
Chronic disease can cause tissue and organ damage constituting the largest obstacle to therapy which, in turn, reduces patients ’ quality-adjusted life-year. Degenerative diseases such as osteoporosis, Alzheime... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 9, 2023 Category: Biotechnology Authors: Andang Miatmoko, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Syarifah Sutra Dewangga, Kevin Ksatria Handoko, Purwati, Ram Kumar Sahu and Dewi Melani Hariyadi Tags: Review Source Type: research

LIFTOSCOPE: development of an automated AI-based module for time-effective and contactless analysis and isolation of cells in microtiter plates
The cultivation, analysis, and isolation of single cells or cell cultures are fundamental to modern biological and medical processes. The novel LIFTOSCOPE technology aims to integrate analysis and isolation in... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - February 7, 2023 Category: Biotechnology Authors: Florian Narrog, Richard Lensing, Tobias Piotrowski, Nadine Nottrodt, Martin Wehner, Bastian Nie ßing, Niels König, Arnold Gillner and Robert H. Schmitt Tags: Research Source Type: research

CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo
CD146 is a cell adhesion molecule whose expression profile in human skin has not yet been elucidated. Here, we characterize CD146 expression pattern in human skin, in particular in blood endothelial cells (BEC... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 31, 2023 Category: Biotechnology Authors: Monica Nanni, Dominic R ütsche, Curdin Bächler, Luca Pontiggia, Agnes S. Klar, Ueli Moehrlen and Thomas Biedermann Tags: Research Source Type: research

RN-Autoencoder: Reduced Noise Autoencoder for classifying imbalanced cancer genomic data
In the current genomic era, gene expression datasets have become one of the main tools utilized in cancer classification. Both curse of dimensionality and class imbalance problems are inherent characteristics ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 30, 2023 Category: Biotechnology Authors: Ahmed Arafa, Nawal El-Fishawy, Mohammed Badawy and Marwa Radad Tags: Research Source Type: research

Research progress on black phosphorus hybrids hydrogel platforms for biomedical applications
Hydrogels, also known as three-dimensional, flexible, and polymer networks, are composed of natural and/or synthetic polymers with exceptional properties such as hydrophilicity, biocompatibility, biofunctional... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 30, 2023 Category: Biotechnology Authors: Hao-xuan Li, Kun-chi Zhao, Jia-jia Jiang and Qing-san Zhu Tags: Review Source Type: research

The synergistic and enhancive effects of IL-6 and M-CSF to expand and differentiate functional dendritic cells from human monocytes under serum-free condition
Dendritic cells (DCs) are differentiated from monocytes, and have a strong ability to perform phagocytosis, present antigens and activate T cell immune response. Therefore, DCs are one of the key factors in fi... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 26, 2023 Category: Biotechnology Authors: Chao-Ling Yao and Tsung-Yu Tseng Tags: Research Source Type: research

Tracking unlabeled cancer cells imaged with low resolution in wide migration chambers via U-NET class-1 probability (pseudofluorescence)
Cell migration is a pivotal biological process, whose dysregulation is found in many diseases including inflammation and cancer. Advances in microscopy technologies allow now to study cell migration in vitro, ... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 24, 2023 Category: Biotechnology Authors: Paola Antonello, Diego Morone, Edisa Pirani, Mariagrazia Uguccioni, Marcus Thelen, Rolf Krause and Diego Ulisse Pizzagalli Tags: Methodology Source Type: research

T7Max transcription system
Efficient cell-free protein expression from linear DNA templates has remained a challenge primarily due to template degradation. In addition, the yields of transcription in cell-free systems lag behind transcr... (Source: Journal of Biological Engineering)
Source: Journal of Biological Engineering - January 23, 2023 Category: Biotechnology Authors: Christopher Deich, Brock Cash, Wakana Sato, Judee Sharon, Lauren Aufdembrink, Nathaniel J. Gaut, Joseph Heili, Kaitlin Stokes, Aaron E. Engelhart and Katarzyna P. Adamala Tags: Research Source Type: research