Forsythia suspensa (Thunb.) Vahl extract ameliorates ulcerative colitis via inhibiting NLRP3 inflammasome activation through the TLR4/MyD88/NF ‐κB pathway
ConclusionIn conclusion, PHI possesses significant anti-inflammatory properties and is expected to be a potential drug for UC treatment. Our study delves into the underlying mechanisms of PHI therapy and highlights the potential for further research in developing PHI-based treatments for UC. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 7, 2023 Category: Allergy & Immunology Authors: Xiao Tong,
Li Chen,
Shijun He,
Shuangshuang Liu,
Jiaying Yao,
Zhenguang Shao,
Yang Ye,
Sheng Yao,
Zemin Lin,
Jianping Zuo Tags: ORIGINAL ARTICLE Source Type: research
A systematic review and meta ‐analysis of investigating the mutual impact of COVID‐19 and psoriasis: Focusing on COVID‐19 course in psoriasis and the opinion on biologics in this setting
ConclusionStudies have shown that biologic therapy for psoriasis did not increase the risk of hospitalization due to COVID-19 infection and may have even offered some protection. Treatment adherence was higher in psoriasis patients receiving biologic therapies than those receiving conventional therapies. These findings suggest that psoriasis treatment did not negatively impact COVID-19 infection and that treatment could be continued on a case-by-case basis during the pandemic. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 7, 2023 Category: Allergy & Immunology Authors: Nazila Ghoreishi Amin,
Sepehr Khosravi,
Najmolsadat Atefi,
Farnoosh Seirafianpour,
Sahand Farhoodi,
Azadeh Goodarzi Tags: REVIEW ARTICLE Source Type: research
Cognitive implications of rheumatoid arthritis: A call for comprehensive care and research focus
(Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 7, 2023 Category: Allergy & Immunology Authors: Marium Qidwai,
Khadija Ahmed,
Muhammad Fawad Tahir,
Sean Kaisser Shaeen,
Muhammad Hasanain,
Abdullah Malikzai Tags: COMMENTARY Source Type: research
TGF ‐β/Smads signaling pathway, Hippo‐YAP/TAZ signaling pathway, and VEGF: Their mechanisms and roles in vascular remodeling related diseases
TGF- β/Smads signaling pathway, Hippo-YAP/TAZ signaling pathway, and vascular endothelial growth factor: their mechanisms and roles in vascular remodeling related diseases. AbstractVascular remodeling is a basic pathological process in various diseases characterized by abnormal changes in the morphology, structure, and function of vascular cells, such as migration, proliferation, hypertrophy, and apoptosis. Various growth factors and pathways are involved in the process of vascular remodeling. The transforming growth factor- β (TGF-β) signaling pathway, which is mainly mediated by TGF-β1, is an important factor in vasc...
Source: Immunity, Inflammation and Disease - November 7, 2023 Category: Allergy & Immunology Authors: Hui Liu,
Mingyue Sun,
Nan Wu,
Bin Liu,
Qingxin Liu,
Xueli Fan Tags: REVIEW ARTICLE Source Type: research
Issue Information
(Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 4, 2023 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research
Clinical characteristics and risk factors of Helicobacter pylori infection ‐associated Sjogren's syndrome
ConclusionTogether, our findings demonstrated that hypergammaglobulinemia could be the independent risk factors ofH. pylori infection in patients with Sjogren's syndrome, requiring the physician's advice in the future. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 31, 2023 Category: Allergy & Immunology Authors: Ye He,
Lingzhen Hu,
Wei Qiu,
Lixia Zhu,
Xiaochun Zhu,
Mingzhi Hong Tags: ORIGINAL ARTICLE Source Type: research
SAMD1 attenuates antiphospholipid syndrome ‐induced pregnancy complications
ConclusionSAMD1 may reduce APS-induced embryo loss by regulating cellular senescence, proliferation, migration, and angiogenesis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 30, 2023 Category: Allergy & Immunology Authors: Ran An,
Yanqi Yang,
Lei Liu,
Peiling Li Tags: ORIGINAL ARTICLE Source Type: research
Chrysosplenol D can inhibit the growth of prostate cancer by inducing reactive oxygen species and autophagy
ConclusionCHD could serve as a drug for prostate cancer. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 30, 2023 Category: Allergy & Immunology Authors: Haoyu Zhang,
Zhixin You,
Yilei Li,
Cheng Gao,
Yuhao Wang,
Xiaoxiang Zhang Tags: ORIGINAL ARTICLE Source Type: research
Examining the relationship between inflammatory biomarkers during COVID ‐19 hospitalization and subsequent long‐COVID symptoms: A longitudinal and retrospective study
ConclusionsOur data demonstrate that female patients present more often with lower levels of inflammatory biomarkers on admission which are subsequently associated with long-term post-COVID symptoms, such as myalgia and anxiety, in those discharged from hospital with severe COVID-19. Further research is needed into the role of serum biomarkers in post-COVID prognostication. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 30, 2023 Category: Allergy & Immunology Authors: Dominic L. Sykes,
Christina M. Van der Feltz ‐Cornelis,
Luke Holdsworth,
Simon P. Hart,
Joseph O'Halloran,
Steve Holding,
Michael G. Crooks Tags: ORIGINAL ARTICLE Source Type: research
Down ‐regulation of OIP5‐AS1 inhibits obesity‐induced myocardial pyroptosis and miR‐22/NLRP3 inflammasome axis
ConclusionOur results revealed that downregulation of OIP5-AS1 can inhibit obesity-induced myocardial pyroptosis via miR-22/NLRP3 inflammasome axis. This finding lays a foundation of gene therapy for heart disease targeting OIP5-AS1. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 28, 2023 Category: Allergy & Immunology Authors: Qingxiong Yue,
Yan Liu,
Jun Ji,
Tao Hu,
Tong Lin,
Shuang Yu,
Shijun Li,
Nan Wu Tags: ORIGINAL ARTICLE Source Type: research
LncRNA HOTAIR regulates the PI3K/AKT pathway via the miR ‐126‐3p/PIK3R2 axis to participate in synovial angiogenesis in rheumatoid arthritis
ConclusionLncRNA HOTAIR has the potential to activate the PI3K/AKT pathway, likely through the regulatory axis involving miR-126-3p/PIK3R2, consequently contributing to synovial angiogenesis in RA. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 27, 2023 Category: Allergy & Immunology Authors: Feifei Liu,
Yuan Wang,
Dan Huang,
Yanqiu Sun Tags: ORIGINAL ARTICLE Source Type: research
Analysis of gastrin ‐17 and its related influencing factors in physical examination results
ConclusionsG17 secretion is closely related to PG andH. pylori. Combined screening contributes to early screening of gastrointestinal diseases in normal people or groups at high risk for gastric cancer, but the influence of inflammatory indicators on G17 should be excluded to improve the reliability of the results. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 27, 2023 Category: Allergy & Immunology Authors: Junchao Zeng,
Yan Shen,
Sanping Xu,
Rui Yang Tags: ORIGINAL ARTICLE Source Type: research
Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway
ConclusionDownregulation of FMOD attenuated inflammatory signaling and atrial fibrosis in SHR-AF by inhibiting the TLR4/NLRP3 signaling pathway. Therefore, FMOD may be a promising therapeutic target in AF. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 27, 2023 Category: Allergy & Immunology Authors: Yuming Liang,
Yun Zhou,
Jialin Wang,
Yan He Tags: ORIGINAL ARTICLE Source Type: research
Association of IL ‐17 and IL‐27 polymorphisms with susceptibility to recurrent pregnancy loss and pre‐eclampsia: A systematic review and meta‐analysis
ConclusionsThe IL-17 rs763780, IL-27 rs153109, and IL-27 rs17855750 polymorphisms were not significantly associated with RPL and PE, whereas the IL-17 rs2275913 polymorphism was associated with the susceptibility to recurrent miscarriage. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 26, 2023 Category: Allergy & Immunology Authors: Yue Ma,
Mingyue Ma,
Shenglong Ye,
Yuanying Liu,
Xueqing Zhao,
Yongqing Wang Tags: ORIGINAL ARTICLE Source Type: research
Dendritic cell immunoreceptor 2 (DCIR2) deficiency decreases hepatic conventional dendritic cell content but not the progression of diet ‐induced obesity
ConclusionOur data show that DCIR2 has a redundant role in the progression of diet-induced obesity and inflammation. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 25, 2023 Category: Allergy & Immunology Authors: Rossella Bellini,
Annalisa Moregola,
Jasmine Nour,
Patrizia Uboldi,
Fabrizia Bonacina,
Giuseppe D. Norata Tags: SHORT REPORT Source Type: research
