The emerging role of IL ‐38 in diseases: A comprehensive review
ConclusionThis article provides a comprehensive review of the association between interleukin-38 and related diseases, using interleukin-38 as a keyword and searching the relevant literature through Pubmed and Web of science up to July 2023. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - August 28, 2023 Category: Allergy & Immunology Authors: Weijun Chen, Shuangyun Xi, Yong Ke, Yinlei Lei Tags: REVIEW ARTICLE Source Type: research

Therapeutic strategies and promising vaccine for hepatitis C virus infection
AbstractHepatitis C virus (HCV) infection is still a significant global health problem despite therapeutic advancements. Ribavirin and interferon therapy have been the sole available treatments for HCV infection for a number of years with low efficacy. Thus, currently, a number of therapeutic strategies are being used, including nanoparticles (NPs), micro-RNAs such as small interfering RNA (siRNA), RNAi-based gene silencing and antisense oligonucleotide-based microRNA-122, microRNA-155, and short hairpin RNAs (shRNAs), and immunotherapeutic approaches such as anti-programmed cell death 1(PD-1), monoclonal antibodies (mAb ...
Source: Immunity, Inflammation and Disease - August 28, 2023 Category: Allergy & Immunology Authors: Adane Adugna Tags: REVIEW ARTICLE Source Type: research

The central role of neutrophil extracellular traps (NETs) and by ‐products in COVID‐19 related pulmonary thrombosis
The respiratory tract is primarily infected by SARS-CoV-2. The primary cause of mortality for COVID-19 was acute respiratory distress syndrome (ARDS), which can be brought on by a lung infection. This review we mainly discuss the mechanism that favor NETosis in COVID-19 immune pulmonary thrombosis, as well as the potential targeting of NETs in COVID-19 patients. AbstractExtracellular trap networks (neutrophil extracellular traps [NETs]) of polymorphonuclear neutrophils are mesh-like substances that prevent the spread of pathogens. They primarily consist of DNA skeletons, histones, granule components, and cytoplasmic protei...
Source: Immunity, Inflammation and Disease - August 28, 2023 Category: Allergy & Immunology Authors: Shi Li, Hui Wang, Qixiang Shao Tags: REVIEW ARTICLE Source Type: research

First ‐ever Marburg virus disease outbreak in Equatorial Guinea and Tanzania: An imminent crisis in West and East Africa
The Marburg virus causes the severe infectious disease known as Marburg Virus Disease (MVD). Previously, different outbreaks of MVD have appeared in different African countries. For the first time, Equatorial Guinea and Tanzania are experiencing MVD outbreaks. In affected regions of Equatorial Guinea and Tanzania, surveillance and detection efforts, including contact tracing and active case finding, are recommended. AbstractThe Marburg virus, which is a member of the same virus family as the Ebola virus called Filoviridae, causes the severe infectious disease known as Marburg virus disease (MVD). Previously, different outb...
Source: Immunity, Inflammation and Disease - August 28, 2023 Category: Allergy & Immunology Authors: Olivier Sibomana, Emmanuel Kubwimana Tags: COMMENTARY Source Type: research

Clinical efficacy, safety, and subjective experience based on ePRO in HIV ‐infected individuals administered Bictegravir/Emtricitabine/Tenofovir Alafenamide in southwest China
ConclusionBIC/FTC/TAF  reduces the viral load in ART-naïve patients with high viral load as well as ART-experienced patients with residual viremia. The patient's subjective experience was maintained stable after treatment with BIC/FTC/TAF. This study also revealed a very low incidence for BIC/FTC/TAF drug-related sid e effects. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - August 28, 2023 Category: Allergy & Immunology Authors: Linghong Kong, Xiaoxin Xie, Yanhua Fu, Lin Gan, Xiaoyan Yang, Shujing Ma, Hai Long Tags: ORIGINAL ARTICLE Source Type: research