Clinical and virological features of asymptomatic and mild symptomatic patients with SARS ‐CoV‐2 Omicron infection at Shanghai Fangcang shelter hospital
ConclusionAsymptomatic and symptomatic patients with non-severe SARS-CoV-2 Omicron BA.2.2 variant infection have similar clinical features and virological courses. Old age was an independent risk factor for prolonged SARS-CoV-2 conversion time. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 27, 2023 Category: Allergy & Immunology Authors: Lin Zhang,
Xiaoyu Kang,
Liangliang Wang,
Rui Yan,
Yanglin Pan,
Jiuping Wang,
Zhangqian Chen Tags: ORIGINAL ARTICLE Source Type: research
Assessing the acceptability of COVID ‐19 vaccine and its booster dose
ConclusionOverall, our results emphasize a positive response and a positive attitude toward COVID-19 vaccination. In addition, define the groups to be targeted with effective communication regarding the COVID-19 vaccine and its booster dose. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 27, 2023 Category: Allergy & Immunology Authors: Sawsan Mubarak,
Ashraf A'aqoulah,
Hadeel AlGhawrie,
Samir Albalas,
Nisreen Innab Tags: ORIGINAL ARTICLE Source Type: research
Immunomodulatory approaches in managing lung inflammation in COVID ‐19: A double‐edge sword
ConclusionThe present review discusses promising immunomodulatory approaches to manage lung inflammation in COVID-19 cases which may serve as potential therapeutic options in the future and may prove lifesaving. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Geetika Verma,
Manish Dhawan,
AbdulRahman A. Saied,
Geetika Kaur,
Reetesh Kumar,
Talha Bin Emran Tags: REVIEW ARTICLE Source Type: research
High ‐fat diet aggravates the severity of the in vitro posttraumatic osteoarthritis model through macrophagic FBW7
In conclusion, this study provides novel insights into the pathological mechanisms underlying HFD-related OA development by identifying the role of FBW7 in synovial macrophages. These findings open up new avenues for research and therapeutic intervent ions targeting HFD-related OA. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Lijun Duan,
Yuan Ma,
Chen ‐Guang Feng,
Xing Yu Tags: ORIGINAL ARTICLE Source Type: research
Analyze the clinical effect of YAG laser combined with sodium hypochlorite in root canal treatment of pulpitis
ConclusionCompared with root canal irrigation with 1% sodium hypochlorite alone, sodium hypochlorite combined with Nd: YAG laser for root canal disinfection can significantly improve the therapeutic effect, relieve inflammatory reaction, and decrease bacterial infection. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Qiaolin Lin,
Zhixin Li,
Mingming Liu Tags: ORIGINAL ARTICLE Source Type: research
Dense fine speckled nuclear immunofluorescence: A mildly reassuring antinuclear antibody pattern meriting consideration
ConclusionsAlthough more studies are needed in this field, it seems reasonable to ascertain the presence of anti-DFS70 in routine clinical practice. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Aleksandra Fija łkowska,
Robert A. Schwartz,
Anna Woźniacka Tags: SHORT REPORT Source Type: research
Alteration of indicator gut microbiota in patients with chronic sinusitis
ConclusionAlthough the more research is needed, possibly the gut microbiota indicator bacteria number analyses might enable to plan personalized prebiotic and probiotic treatment, which could support intestine microbiota and mucosal immunity patients suffering from chronic sinusitis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Micha ł Michalik,
Adrianna Podbielska‐Kubera,
Anna Maria Basińska,
Monika Szewc,
Mirosława Gałęcka,
Andreas Schwiertz Tags: ORIGINAL ARTICLE Source Type: research
Neutrophil ‐to‐lymphocyte ratio in relation to trauma severity as prognosis factors in patients with multiple injuries complicated by multiple organ dysfunction syndrome: A retrospective analysis
Conclusiond-dimer level, ISS, NLR, and CS-24h are important risk factors for MODS in patients with multiple injuries. Notably, NLR expression may be a good indicator of injury severity and predictor of the occurrence of MODS in patients with multiple injuries. Therefore, assessment of injury severity and coagulation function, active resuscitation, as well as prevention of infection should be emphasized during treatment of multiple injuries, to reduce and prevent the risk of MODS in patients with multiple injuries. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Yong ‐Ming He,
Xing Liu,
Si‐Yi Zhong,
Qiu‐Hong Fu Tags: ORIGINAL ARTICLE Source Type: research
Cathelicidin (LL ‐37) causes expression of inflammatory factors in coronary artery endothelial cells of Kawasaki disease by activating TLR4–NF‐κB–NLRP3 signaling
ConclusionsOur data suggest that LL-37 induces an inflammatory response in KD coronary endothelial cells via TLR4-NF- κB-NLRP3, providing a potential target for the treatment of KD. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Feifei Si,
Yaheng Lu,
Yizhou Wen,
Tingting Chen,
Yingzi Zhang,
Yanfeng Yang Tags: ORIGINAL ARTICLE Source Type: research
Interaction among inflammasome, PANoptosise, and innate immune cells in infection of influenza virus: Updated review
ConclusionA comprehensive understanding of the dynamic interactions between PANoptosis, Inflammasomes, and IV is essential for advancing our knowledge of innate immune responses to viral infections. This knowledge will be invaluable in developing targeted antiviral therapies to combat IV and mitigate potential complications, including cytokine storms and tissue damage. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 26, 2023 Category: Allergy & Immunology Authors: Li Wei,
Xufang Wang,
Huifei Zhou Tags: REVIEW ARTICLE Source Type: research
Activating transcription factor 3: A potential therapeutic target for inflammatory pulmonary diseases
ConclusionsIn this review, we first summarized the structure, function, and mechanism of ATF3 in various inflammatory pulmonary diseases. The impact of ATF3 on disease pathogenesis and the clinical implications was particularly focused on, with an overall aim to identify new targets for treating inflammatory pulmonary diseases. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 23, 2023 Category: Allergy & Immunology Authors: Dandan Li,
Juanjuan Jing,
Xue Dong,
Chenyang Zhang,
Jia Wang,
Xianyao Wan Tags: REVIEW ARTICLE Source Type: research
Cardiac troponin as a prognosticator of mortality in patients with sepsis: A systematic review and meta ‐analysis
ConclusionsOverall, our finding revealed that elevated cardiac troponin for sepsis patients was a predictor of hospital and long-term mortality. Clinicians may treat septic patients with elevated cardiac troponin more cautious to avoid extra death. Moreover, large clinical studies are warranted to validate this association. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 22, 2023 Category: Allergy & Immunology Authors: Peiqiu Zheng,
Xing Wang,
Tao Guo,
Wei Gao,
Qiang Huang,
Jie Yang,
Hui Gao,
Qian Liu Tags: ORIGINAL ARTICLE Source Type: research
Safety and efficacy of mesenchymal stem cells in COVID ‐19 patients: A systematic review and meta‐analysis
ConclusionsMSCs are a viable therapy option for COVID-19 because of their safety and potential efficacy. With no significant adverse effects, MSCs can reduce mortality, clinical symptom improvement time, and days to hospital discharge, improve clinical symptoms, and reduce inflammatory cytokines CRP in COVID-19. However, further high-quality clinical studies are required to confirm these results. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 22, 2023 Category: Allergy & Immunology Authors: Cai Yan,
Minjie Hu,
Rongjuan Dai Tags: REVIEW ARTICLE Source Type: research
Mitochondrial dynamics modulate the allergic inflammation in a murine model of allergic rhinitis
ConclusionOur findings reveal mitochondrial dynamics modulate the allergic responses in AR. Mitochondrial dynamics may represent a promising target for the treatment of AR. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 22, 2023 Category: Allergy & Immunology Authors: Xu ‐qing Chen,
Long‐yun Zhou,
Hua‐an Ma,
Ji‐yong Wu,
Shu‐fen Liu,
Yong‐jun Wu,
Dao‐nan Yan Tags: ORIGINAL ARTICLE Source Type: research
Diagnostic values of serum BNP, PTX3, and VEGF in acute pulmonary embolism complicated by pulmonary artery hypertension and their correlations with severity of pulmonary artery hypertension
ConclusionSerum BNP, PTX3, and VEGF levels are significantly elevated in APE-PAH patients. Serum BNP, PTX3, and VEGF levels are of clinical value in the diagnosis of APE-PAH patients, and serum BNP, PTX3, and VEGF levels are positively correlated with the severity of PAH and can be used as predictors of the severity of PAH. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - September 21, 2023 Category: Allergy & Immunology Authors: Qinghou Zheng,
Bin Zhang,
Na Lu,
Xinyi Li,
Beibei Jin,
Pingkui Jin Tags: ORIGINAL ARTICLE Source Type: research
