Inflammatory biomarker changes in healthy adults secondary to electronic cigarette use: A scoping review
ConclusionThe results of studies evaluated in our scoping review suggested that short-term use of nicotine-containing ECs may result in increased CV and oxidative stress inflammation, contributing to potential CV or neurologic disease development. The results of studies evaluated in our scoping review also suggested that long-term use of nicotine-containing ECs resulted in no significant changes in general inflammatory biomarker levels. A rigorous systematic review and meta-analysis is necessary to corroborate our findings and to determine the effect of long-term EC use on MMP-9 and IL-6 levels. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 2, 2024 Category: Allergy & Immunology Authors: Shawn Boss,
Michael Bertolio,
Laura Lipke Tags: REVIEW ARTICLE Source Type: research
Potential clinical implications of molecular mimicry ‐induced autoimmunity
ConclusionsMolecular mimicry plausibly explains initial stages of autoimmune pathogenesis induced by infection or microbiota disturbances. Understanding mimicry antigens and pathways could enable improved prediction, monitoring, and antigen-specific immunotherapy for autoimmune disorders. However, definitive proof of causation in humans remains limited. Further research should focus on establishing clinical evidence and utility. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 1, 2024 Category: Allergy & Immunology Authors: Bandar A Suliman Tags: REVIEW ARTICLE Source Type: research
Serological detection of Newcastle disease virus in backyard poultry production system in Woliso District South West Shewa, Central Ethiopia
ConclusionFrom the finding, we conclude that indirect ELISA test detected the presence of the NDV in the study area and the heterogeneousity of antibody titer in the study area. Therefore, further molecular characterization and epidemiological investigation should be carried and vaccination of animals is critical in the study area. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 1, 2024 Category: Allergy & Immunology Authors: Alemayehu Choramo,
Motuma Debelo,
Asamenew Tesfaye,
Chala Bedasa,
Chala Dima,
Chala Guyassa Tags: ORIGINAL ARTICLE Source Type: research
Elucidating systemic immune responses to acute and convalescent SARS ‐CoV‐2 infection in children and elderly individuals
ConclusionThus, COVID-19 children are characterized by distinct cytokine/chemokine/growth factor/acute phase protein markers that are markedly different from elderly COVID-19 individuals. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 1, 2024 Category: Allergy & Immunology Authors: Anuradha Rajamanickam,
Pavan Kumar Nathella,
Aishwarya Venkataraman,
Padmapriyadarsini Chandrasekaran,
Sasidaran Rajendraprasath,
Bella D. Devaleenal,
Arul Nancy Pandiarajan,
Gowshika Krishnakumar,
Padmasani Venkat Ramanan,
Subash Babu Tags: ORIGINAL ARTICLE Source Type: research
Adalimumab exhibits superiority over etanercept in terms of a numerically higher response rate and equivalent adverse events: A real ‐world finding
ConclusionADA shows superiority over ETN in terms of a numerically greater response rate and equivalent adverse events. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 1, 2024 Category: Allergy & Immunology Authors: Zhe Yu,
Ling Gao,
Yinshan Zang,
Lu Cheng,
Wenjia Gao,
Yan Xu Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 1, 2024 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research
Efficacy, safety and the lymphocyte subsets changes of low ‐dose IL‐2 in patients with systemic lupus erythematosus: A systematic review and meta‐analysis
ConclusionLD-IL-2 was promising and well-tolerated in treating SLE, which could promote Treg's proliferation and functional recovery. Injecting 0.5 million IU of IL-2 daily can better induce the differentiation of Treg cells and maintain immune homeostasis than injecting 1 million IU every other day. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 25, 2024 Category: Allergy & Immunology Authors: Qin ‐Yi Su,
Jing Luo,
Xin‐Miao Wang,
Jing‐Kai Di,
Yi‐Xin Cao,
Sheng‐Xiao Zhang Tags: REVIEW ARTICLE Source Type: research
Circ_0087199 depletion attenuates lipopolysaccharides ‐induced human periodontal ligament cell injury through the miR‐527/TLR4 axis
ConclusionCirc_0087199 knockdown attenuated LPS-induced apoptosis, inflammation and oxidative stress of PDLCs by regulating the miR-527/TLR4 pathway. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 25, 2024 Category: Allergy & Immunology Authors: Jing Wang,
Na Huo,
Chuan Cai,
Yu Zhang,
Rui Xiao Tags: ORIGINAL ARTICLE Source Type: research
Cordyceps cicadae ameliorates inflammatory responses, oxidative stress, and fibrosis by targeting the PI3K/mTOR ‐mediated autophagy pathway in the renal of MRL/lpr mice
ConclusionsThe findings of the present research showed thatC. cicadae could alleviate inflammatory responses, oxidative stress, and fibrosis in the renal tissues of mice with LN by targeting the PI3K/mTOR-mediated autophagy pathway. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 25, 2024 Category: Allergy & Immunology Authors: Feng Yang,
Yanyan Zhang,
Lei Dong,
Zhichao Song Tags: ORIGINAL ARTICLE Source Type: research
Exploring the effect of LncRNA DANCR to regulate the Keap1 ‐Nrf2/ARE pathway on oxidative stress in rheumatoid arthritis
ConclusionThe low-expressed LncRNA DANCR may regulate the Keap1-Nrf2/ARE pathway and suppress the inflammatory and oxidative responses in RA patients. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 24, 2024 Category: Allergy & Immunology Authors: Shaohong Cai,
Yue Sun,
Yuan Wang,
Zhangying Lin Tags: REVIEW ARTICLE Source Type: research
Bibliometric analysis of mucosal immunity in IgA nephropathy from 1990 to 2022
ConclusionThis was the first bibliometric analysis to systematically analyze the mucosal immunity in IgAN, which obtained the current status and indicated the future research hotspots and development trends. The gut microbiota and the related therapy-targeted mucosal immunity might be the future research hotspot. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 24, 2024 Category: Allergy & Immunology Authors: Xian Chen,
Zhe Yan,
Qing Pan,
Chunxia Zhang,
Yakun Chen,
Xuzhi Liang,
Shaomei Li,
Gang Wu Tags: ORIGINAL ARTICLE Source Type: research
m5C regulator ‐mediated methylation modification patterns and tumor microenvironment infiltration characteristics in acute myeloid leukemia
ConclusionsThis study shows that m5C modification may be one of the key roles in the formation of diversity and complexity of TME. Meanwhile, assessing the patterns of m5C modification among individual cancer samples is of great importance, which provides insights into cell infiltration features within TME, thereby helping to develop relevant immunotherapy and predict patient prognostic outcomes. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 23, 2024 Category: Allergy & Immunology Authors: Qiang Wen,
ShouJun Wang,
Lili Hong,
Siyu Shen,
Yibo He,
Xianfu Sheng,
Xiaofen Zhuang,
Shiliang Chen,
Ying Wang,
Haifeng Zhuang Tags: ORIGINAL ARTICLE Source Type: research
Effect of serum inflammatory factors in predicting co ‐infection with influenza viruses and Omicron
ConclusionThe findings suggest that prealbumin is a valuable indicator that can warn of co-infection and guide timely treatment decisions. Joint prediction may offer an even more effective diagnostic tool for discriminating co-infection from mono-infection. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 22, 2024 Category: Allergy & Immunology Authors: Chengli Zhang,
Wei Wang,
Xianglin Luo,
Minggang Yin,
Xiaolong Guo Tags: SHORT REPORT Source Type: research
Analysis of intestinal flora in elderly Uygur patients with sarcopenia
ConclusionIn conclusion, Lachnoclostridium is significantly enriched in the intestines of elderly Uygur patients with sarcopenia; the increase in Lachnoclostridium abundance and the decrease in Streptobacillus abundance are associated with high levels of IL-6. Therefore, abnormal intestinal flora is related to inflammatory reflexes in patients with sarcopenia. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 22, 2024 Category: Allergy & Immunology Authors: Zimei Shan,
Na Cheng,
Jia Zhu,
Fei Chen,
Jiani Ji,
Meilibana Tags: ORIGINAL ARTICLE Source Type: research
Alleviating effect of Nexrutine on mucosal inflammation in mice with ulcerative colitis: Involvement of the RELA suppression
ConclusionThis study demonstrates that Nexrutine alleviates inflammatory mucosal barrier damage in UC by suppressing RELA transcription. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 20, 2024 Category: Allergy & Immunology Authors: Hongyun Xu,
Chunyu Wu,
Danning Wang,
Haiqiang Wang Tags: ORIGINAL ARTICLE Source Type: research
