Mechanistic insights into the role of probiotics in modulating immune cells in ulcerative colitis
ConclusionProbiotics demonstrate significant potential in modulating the immune reactions in UC. Their capacity to modulate different immune cells and inflammation-related processes makes them a promising therapeutic approach for managing UC. However, further studies are warranted to optimize their use and fully elucidate the molecular mechanisms underlying their beneficial effects in UC treatment. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 13, 2023 Category: Allergy & Immunology Authors: Ni Guo,
Lu ‐lu Lv Tags: REVIEW ARTICLE Source Type: research
Mechanism of KLF9 in airway inflammation in chronic obstructive pulmonary
ConclusionKLF9 bound to the miR-494-3p promoter and repressed PTEN expression, thereby facilitating NLRP3 inflammasome-mediated inflammation. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 12, 2023 Category: Allergy & Immunology Authors: Peijie Gu,
Zhen Wang,
Xin Yu,
Nan Wu,
Liang Wu,
Yihang Li,
Xiaodong Hu Tags: ORIGINAL ARTICLE Source Type: research
Effect of lidocaine on cognitively impaired rats: Anti ‐inflammatory and antioxidant mechanisms in combination with CRMP2 antiphosphorylation
ConclusionsLidocaine was shown to reduce cognitive impairment in rats with cognitive dysfunction through anti-inflammatory and antioxidative stress mechanisms in combination with CRMP2 antiphosphorylation. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 11, 2023 Category: Allergy & Immunology Authors: Xiaohong Zheng,
Yuerong Lin,
Linshen Huang,
Xianzhong Lin Tags: ORIGINAL ARTICLE Source Type: research
Clinical efficacy of plasma exchange in systemic lupus erythematosus during pregnancy
ConclusionsThe combination of PE and oral prednisone and HCQ is possibly a more effective treatment than oral prednisone and HCQ alone for patients with active SLE during pregnancy. This treatment option reduces pregnancy loss and promotes the patients' postpartum condition to a certain extent. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 11, 2023 Category: Allergy & Immunology Authors: Fen Zhang,
Bing ‐Ying Zhang,
Ru Fan,
Ting Cheng,
Xiao‐Rong Hu,
Yu‐Qing Liu,
Xing Cen,
Yu‐Jie Bu,
Jian‐Ping Cao,
Feng‐Wu Chen,
Jun‐Wei Chen Tags: ORIGINAL ARTICLE Source Type: research
Identification of ferroptosis ‐related genes in type 2 diabetes mellitus based on machine learning
ConclusionsThe diagnosis and aetiology of T2DM can be greatly aided by eight FRGs, providing novel therapeutic avenues. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 11, 2023 Category: Allergy & Immunology Authors: Sen Wang,
Yongpan Lu,
Tingting Chi,
Yixin Zhang,
Yuli Zhao,
Huimin Guo,
Li Feng Tags: ORIGINAL ARTICLE Source Type: research
COVID ‐associated arthritis after severe and non‐severe COVID‐19: A systematic review
ConclusionWe conclude that there may be an inverse relationship between COVID-19 severity and arthritis severity, possibly due to weaker immunity conditions following immunosuppressant treatments in patients with severe COVID-19. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 11, 2023 Category: Allergy & Immunology Authors: Mahsa Zarpoosh,
Parsa Amirian Tags: REVIEW ARTICLE Source Type: research
Machine learning identification and immune infiltration of disulfidptosis ‐related Alzheimer's disease molecular subtypes
ConclusionWe identified disulfidptosis-related molecular clusters in AD and established a novel risk model to assess the likelihood of developing AD. These findings revealed a complex association between disulfidptosis and AD, which may aid in identifying potential therapeutic targets for this debilitating disorder. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 11, 2023 Category: Allergy & Immunology Authors: Yidong Zhu,
Lingyue Kong,
Tianxiong Han,
Qiongzhi Yan,
Jun Liu Tags: ORIGINAL ARTICLE Source Type: research
Heat stress combined with lipopolysaccharide induces pulmonary microvascular endothelial cell glycocalyx inflammatory damage in vitro
This study indicated that EGCX may con tribute to apoptosis and heat stroke-induced coagulopathy, and these effects may have been due to the decrease in the shedding of EGCX. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 6, 2023 Category: Allergy & Immunology Authors: Jiadi Chen,
Chengjia Ding,
Jingjing Cao,
Huasheng Tong,
Yi Chen Tags: ORIGINAL ARTICLE Source Type: research
Downregulation of BIRC2 hinders the progression of rheumatoid arthritis through regulating TRADD
ConclusionIn summary, BIRC2 knockdown alleviated necroptosis, oxidative stress, and inflammation in LPS-mediated C28/I2 cells, which might correlate to the regulatory role of TRADD, indicating a novel target for the treatment of RA. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 5, 2023 Category: Allergy & Immunology Authors: Yanting Rao,
Shengjing Xu,
Ting Lu,
Yuanyuan Wang,
Manman Liu,
Wei Zhang Tags: ORIGINAL ARTICLE Source Type: research
Neuroprotective mechanism of salvianolic acid B against cerebral ischemia –reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β
ConclusionWe found that Sal B protects brain tissues from I/R injury by activating its anti-inflammatory properties. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 4, 2023 Category: Allergy & Immunology Authors: Xiu ‐fen Zheng,
Xiang‐jian Zhang,
Li‐peng Dong,
Jing‐ru Zhao,
Cong Zhang,
Rong Chen Tags: ORIGINAL ARTICLE Source Type: research
Cerebrospinal fluid proteomics in meningitis patients with reactivated varicella zoster virus
ConclusionInflammatory immune response is an important pathophysiological mechanism of CNS infection by VZV, and the CSF IL-18 levels might be a potential prognostic indicator of the outcomes of VZV meningitis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 4, 2023 Category: Allergy & Immunology Authors: Huili Liu,
Jun Wang,
Yan Zhang,
Jing Gu,
Yu Wang,
Yongxing Yan,
Dongli Pan,
Zeyu Sun Tags: REVIEW ARTICLE Source Type: research
Research progress on the activation mechanism of NLRP3 inflammasome in septic cardiomyopathy
Inflammasomes play a key role in the development and progression of innate immunity and immunoinflammatory diseases. It was found that NLPR3 inflammasomes are closely related to sepsis and septic cardiomyopathy (SCM) and can be involved in regulating SCM through cardiomyocyte inflammatory response and apoptosis, oxidative stress injury, calcium regulation, endoplasmic reticulum stress, mitochondrial dysfunction, and exosomes. AbstractSepsis is an uncontrolled host response to infection, resulting in a clinical syndrome involving multiple organ dysfunctions. Cardiac damage is the most common organ damage in sepsis. Uncontro...
Source: Immunity, Inflammation and Disease - October 4, 2023 Category: Allergy & Immunology Authors: Yuqi Wen,
Yang Liu,
Weihong Liu,
Wenli Liu,
Jinyan Dong,
Qingkuo Liu,
Hao Hao,
Hongsheng Ren Tags: REVIEW ARTICLE Source Type: research
Primary symptoms of severe mycoplasma pneumoniae pneumonia with acute abdomen, scrotal swelling and pain, and fever: A case report
ConclusionSevere MP pneumonia in patients with pediatric diseases may include abdominal pain, scrotal swelling and pain, and fever as the primary symptoms. Care should be taken to avoid missed diagnoses and misdiagnoses in clinical practice. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 4, 2023 Category: Allergy & Immunology Authors: Hui Lei,
Qiong Wang,
Xue ‐min Xiong,
Shengjuan Hu,
Yu Shao,
Rongchang Shao Tags: ORIGINAL ARTICLE Source Type: research
The potential roles of stress ‐induced phosphoprotein 1 and connexin 43 in rats with reperfusion arrhythmia
ConclusionSTIP1 promoted Cx43 expression to improve intercellular communication and reduce oxidative stress in H/R-stimulated H9C2 cells. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 3, 2023 Category: Allergy & Immunology Authors: Li An,
Hong Gao,
Yi Zhong,
Yanqiu Liu,
Ying Cao,
Jing Yi,
Xiang Huang,
Chunlei Wen,
Rui Tong,
Zhijun Pan,
Xu Yan,
Meiyan Liu,
Shengzhao Wang,
Hao Wu,
Tingju Hu Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - October 3, 2023 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research
