Changes in intestinal flora of mice induced by rEg.P29 epitope peptide vaccines
ConclusionIn this study, we comprehensively analyzed and compared changes in the intestinal microbiota of mice immunized with three peptide vaccines as well as their related metabolic pathways, providing a theoretical background for the development of novel vaccines againstE. granulosus. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 23, 2023 Category: Allergy & Immunology Authors: Tingting Zhang,
Yongxue Lv,
Yinqi Zhao,
Jihui Yang,
Bingshuo Qian,
Yazhou Zhu,
Wei Zhao,
Mingxing Zhu Tags: ORIGINAL ARTICLE Source Type: research
Impact of the SARS ‐CoV‐2 pandemic on the overall respiratory viruses' transmission in a cancer care setting
ConclusionThis study provides valuable insights into the interplay between COVID-19 and other respiratory viruses, suggesting that the measures taken for COVID-19 were effective in reducing the spread of viral respiratory infections, aiding future infection control strategies to protect vulnerable populations, including cancer patients, from seasonal respiratory infections. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Sawsan Mubarak,
Osama Alsmadi,
Abdelghani Tbakhi,
Osama Abu Ata,
Ala'a Hassan,
Hadeel AlGhawrie Tags: ORIGINAL ARTICLE Source Type: research
Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF ‐1 pathway
ConclusionAPC ameliorates IR in HepG2 cells through activating the STAT5/IGF-1 pathway. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Xinxin Yue,
Wei Hao,
Min Wang,
Yang Fu Tags: ORIGINAL ARTICLE Source Type: research
Cell ‐based therapies for the treatment of rheumatoid arthritis
Stem cell therapy for systemic sclerosis was evaluated. The efficacy of mesenchymal and hematopoietic stem cells was evaluated. Issues, including conditioning regimen, limitations, and complications, were discussed AbstractAutoimmune diseases, including rheumatoid arthritis that is the most prevalent rheumatic autoimmune disorder, affect autologous connective tissues caused by the breakdown of the self-tolerance mechanisms of the immune system. During the last two decades, cell-based therapy, including stem cells and none-stem cells has been increasingly considered as a therapeutic option in various diseases. This is partl...
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Maryam Zare Moghaddam,
Mohammad Javad Mousavi,
Somayeh Ghotloo Tags: REVIEW ARTICLE Source Type: research
High frequency of type I interferon auto ‐antibodies in a group of middle‐aged HIV‐infected patients: A cross‐sectional exploratory study
ConclusionsThis study, which is the first searching auto-antibodies against type I interferons in HIV-infected patients, demonstrated that their prevalence was higher than that expected by the age of these patients. Furthermore, it indicated that these auto-antibodies are nonspecifically increased in critical SARS-CoV-2 infection but can be found also in other infections. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Luisa Imberti,
Paola Magro,
Alessandra Sottini,
Virginia Quaresima,
Francesco Castelli,
Eugenia Quiros ‐Roldan Tags: SHORT REPORT Source Type: research
Long ‐term oral administration of burdock fructooligosaccharide alleviates DSS‐induced colitis in mice by mediating anti‐inflammatory effects and protection of intestinal barrier function
ConclusionBFO effectively alleviated the symptoms of DSS-induced colitis by mediating anti-inflammatory effects and protecting the intestinal barrier integrity, thereby potentially facilitating the utilization of safer and more efficacious polysaccharides for managing chronic inflammatory diseases. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Qunfei Ma,
Xiujuan Zhang,
Xuan Xu,
Yan Lu,
Qiang Chen,
Yiru Chen,
Chunyan Liu,
Kaoshan Chen Tags: ORIGINAL ARTICLE Source Type: research
Clinical efficacy of budesonide combined with acetylcysteine in the treatment of mycoplasma pneumonia infection
ConclusionBudesonide and N-acetylcysteine combination therapy in the treatment of MP infection in children has a significant effect, and can quickly relieve the clinical symptoms of children with good safety. It is worthy of widespread clinical use. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Jing Chen,
Ying Zhu,
Chunfeng Zheng,
Wei Zhao,
Qi Liu Tags: ORIGINAL ARTICLE Source Type: research
Identification of a 17 kDa protein that is a potentially novel antigen of lettuce‐associated respiratory allergy in farmers
ConclusionA 17 kDa protein that is a potentially novel antigen of lettuce-associated respiratory allergy was identified. In further studies, we will focus on purifying this novel protein to diagnose lettuce allergy. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 21, 2023 Category: Allergy & Immunology Authors: Junya Yoshioka,
Tatsuya Nagano,
Reina Sekiya,
Erika Yano,
Naoya Hatano,
Naoko Katsurada,
Masatsugu Yamamoto,
Motoko Tachihara,
Yuichi Uno,
Tatsuya Moriyama,
Yoshihiro Nishimura,
Kazuyuki Kobayashi Tags: ORIGINAL ARTICLE Source Type: research
Correlation between immune ‐related Tryptophan‐Kynurenine pathway and severity of severe pneumonia and inflammation‐related polyunsaturated fatty acids
ConclusionThis study revealed that during severe pneumonia, the Tryptophan-Kynurenine pathway was activated and was positively correlated with the disease progression. On the other hand, the activation of the Tryptophan-Kynurenine pathway was negatively correlated with N-3/N-6 PUFAs. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 20, 2023 Category: Allergy & Immunology Authors: Baojun Guo,
Mingshan Xue,
Teng Zhang,
Hui Gan,
Runpei Lin,
Mingtao Liu,
Yuhong Liao,
Jiali Lyu,
Peiyan Zheng,
Baoqing Sun Tags: ORIGINAL ARTICLE Source Type: research
Identification of potential therapeutic drugs targeting core genes for systemic lupus erythematosus (SLE) and coexisting COVID ‐19: Insights from bioinformatic analyses
ConclusionFour possible drugs that targeted two specific genes, which may be beneficial for COVID-19 patients with SLE. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 20, 2023 Category: Allergy & Immunology Authors: Chao Chen,
Hongjian Zhang,
Yanbin Lin,
Meiqi Lu,
Quan Liao,
Shichao Zhang,
Weibin Chen,
Xiongwei Zheng,
Yunpeng Li,
Rui Ding,
Zheng Wan Tags: ORIGINAL ARTICLE Source Type: research
Evaluation of common protein biomarkers involved in the pathogenesis of respiratory diseases with proteomic methods: A systematic review
ConclusionAlthough these 31 proteins regulate different factors and molecular pathways in all five diseases, they ultimately lead to the regulation of inflammatory pathways. In other words, the expression of some proteins in COPD and mustard-exposed patients increases inflammatory reactions, while in IPF, they cause lung fibrosis. Asthma, causes allergic reactions due to T-cell differentiation toward Th2. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 20, 2023 Category: Allergy & Immunology Authors: Hadi Rezaeeyan,
Masoud Arabfard,
Hamid R. Rasouli,
Alireza Shahriary,
B. Fatemeh Nobakht M. Gh Tags: REVIEW ARTICLE Source Type: research
Resolvin D1 promotes the resolution of inflammation in the ACLF rat model by increasing the proportion of Treg cells
ConclusionA low dose of RvD1 can promote the resolution of inflammation in ACLF rats by increasing the proportion of Treg cells. RvD1, therefore, may be used as a potential drug for the treatment of patients with ACLF. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 20, 2023 Category: Allergy & Immunology Authors: Linjun Chen,
Yixuan Huang,
Yizhen Chen,
Jiaxuan Chen,
Xueye You,
Laiyu Zou,
Jiabing Chen,
Zhixin Chen,
Xiaozhong Wang,
Yuehong Huang Tags: ORIGINAL ARTICLE Source Type: research
Evaluation of the efficacy and safety of oral N ‐acetylcysteine in patients with COVID‐19 receiving the routine antiviral and hydroxychloroquine protocol: A randomized controlled clinical trial
ConclusionThe NAC could be more effective as prophylactic or adjuvant therapy in stable non-severe cases of COVID-19 with a particularly positive role in the augmentation of O2 saturation and faster reduction of the CRP level and inflammation or could be effective for better controlling of COVID-19 or its therapy-related side effects. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 20, 2023 Category: Allergy & Immunology Authors: Najmolsadat Atefi,
Azadeh Goodarzi,
Taghi Riahi,
Niloofar Khodabandehloo,
Mahshid Talebi Taher,
Niloufar Najar Nobari,
Farnoosh Seirafianpour,
Zeinab Mahdi,
Amir Baghestani,
Rohollah Valizadeh Tags: ORIGINAL ARTICLE Source Type: research
Clinical characteristics and prognostic analysis of idiopathic inflammatory myopathy with positive anti ‐aminoacyl‐tRNA synthetase antibodies: A single center experience
ConclusionsPatients with ASS accompanied with ILD are highly prevalent. Mechanic's hands, ANA, and ILD may be a potential biomarker for predicting a poor prognosis in patients with ASS. Additionally, the detection of the anti-Ro52 antibody provides valuable insights for managing and predicting disease progression and long-term outcomes. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 18, 2023 Category: Allergy & Immunology Authors: Di Zhang,
Huijing Wang,
Xinpeng Zhou,
Jianguo Yang,
Yuan Liu,
Wenjing Wang,
Ping Jiang,
Bing Fan Tags: ORIGINAL ARTICLE Source Type: research
Evaluation of risk factors for cytomegalovirus DNAemia after end of regular prophylaxis after heart transplantation
ConclusionOur data should raise awareness of CMV-DNAemia after the termination of regular prophylaxis, as this affects one in five HTx patients. Especially old recipients as well as D+/R − and D−/R+ serology share an elevated risk of late CMV-DNAemia. For these patients, prolongation, or repetition of CMV prophylaxis, including antiviral drugs and CMV immunoglobulins, may be considered. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 17, 2023 Category: Allergy & Immunology Authors: Moritz Benjamin Immohr,
Daniel Oehler,
Freya Sophie Jenkins,
Nikolas Kalampokas,
Vincent Hendrik Hettlich,
Dennis Sigetti,
Fabian Vo ß,
Hannan Dalyanoglu,
Hug Aubin,
Payam Akhyari,
Artur Lichtenberg,
Udo Boeken Tags: ORIGINAL ARTICLE Source Type: research
