The effect of COVID ‐19 and COVID‐19 vaccination on serum anti‐Mullerian hormone: A systematic review and meta‐analysis
ConclusionCOVID-19 infection can result in ovarian reserve injury by reducing the AMH level but getting vaccinated against COVID-19 has no impact on the AMH level. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 11, 2024 Category: Allergy & Immunology Authors: Marjan Ghaemi, Sedigheh Hantoushzadeh, Arman Shafiee, Omid Kohandel Gargari, Hanieh Fathi, Nasim Eshraghi, Jafar Razavi, Gholam Reza Habibi, Kyana Jafarabady Tags: REVIEW ARTICLE Source Type: research

Interaction between long noncoding RNA and microRNA in lung inflammatory diseases
ConclusionsNumerous lncRNAs and miRNAs have been found to partipicate in all stages of lung inflammatory diseases. While ncRNA-based therapies have been validated and developed, there remain challenges in developing more stable and effective drugs for clinical use. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Jiaqi Li, Shengyu Huang, Liangliang Shi, Guochang Chen, Xiaoxiao Liu, Mingzhuo Liu, Guanghua Guo Tags: REVIEW ARTICLE Source Type: research

Association of polymorphism of IL ‐17A, IL‐17F, and IL‐6 with Toxoplasma gondii infection susceptibility in HIV/AIDS patients in Shiraz, southern Iran
ConclusionThe findings of this study revealed that there were significant differences in the serum levels of IL-6 and IL-17A, but not IL-17F, between the case and control groups in various genetic models. However, these polymorphisms did not show a significant relationship with toxoplasma infection in HIV-positive patients. This study represents the first investigation in Iran to explore the role of IL-6 and IL-17 polymorphisms in toxoplasma infection among HIV-positive patients. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Maryam Nejabat, Mohammadreza Heydari, Mohammad Motamedifar, Zohre Foroozanfar, Saeid Amirizadeh Fard, Ava Hashempour, Nazani Nazari, Esmaeil Rezaei, Zahra Heydari Tags: ORIGINAL ARTICLE Source Type: research

An integrative model with HLA ‐DR, CD64, and PD‐1 for the diagnostic and prognostic evaluation of sepsis
ConclusionThese findings indicate that the combinations of HLA-DR, CD64, and PD-1 outperformed each of the single indicator in diagnosis and predicting prognosis of sepsis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Guosheng Chen, Huimin Chong, Peng Zhang, Dalin Wen, Juan Du, Chu Gao, Shi Zeng, Ling Zeng, Jin Deng, Kejun Zhang, Anqiang Zhang Tags: ORIGINAL ARTICLE Source Type: research

Clinical features of macrophage activation syndrome in adult dermatomyositis:  A single‐center retrospective case‐control study
ConclusionMAS was a common and fatal complication of dermatomyositis in our cohort. MAS is closely related to RP-ILD in patients with dermatomyositis. When RP-ILD is present in dermatomyositis patients with abnormal laboratory findings, such as cytopenia and hyperferritinemia, the presence of MAS should be considered. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Dingxian Zhu, Shuni Ying, Changyi Yang, Sheng Li, Shunli Tang, Chuanyin Sun, Hong Fang, Jianjun Qiao Tags: ORIGINAL ARTICLE Source Type: research

Sirtuin 3 is required for the dexmedetomidine ‐mediated alleviation of inflammation and oxidative stress in nephritis
ConclusionsOur results suggest that DEX exhibits renoprotective activity during nephritis progression, protecting renal cells against inflammatory injury by promoting SIRT3 expression. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Kai Lu, Xinlong Li, Jie Wu Tags: ORIGINAL ARTICLE Source Type: research

Human chorionic gonadotrophin indirectly activates peripheral γδT cells to produce interleukin‐10 during early pregnancy
ConclusionCertain early pregnancy-relevant hCG concentrations could enhance the ratios of peripheral CD69+ and IL-10+γδT cells, contributing to the activation of γδT cells and immunological tolerance during early pregnancy. However, these affects may not be strongly mediated by direct ligand–receptor interactions and they may highly depend on immune microenvironment. Our novel observations propose a perspect ive into the endocrine-immune dialog that exists between the fetus and maternal immune cells. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Liman Li, Yuan Liu, Wenjie Zhou, Chuan Yang, Ting Feng, Hong Li Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of dupilumab plus topical corticosteroids in children with atopic dermatitis: A  meta‐analysis of randomized controlled trials
ConclusionsDupilumab and topical corticosteroids can be used to treat symptoms in children with AD. However, given the substantial variation in treatment outcomes among studies, the findings should be interpreted with caution. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Li Wang, Si ‐Ning Wang, Ruil‐Li Zhang Tags: ORIGINAL ARTICLE Source Type: research

Sufficiently activated mature natural killer cells derived from peripheral blood mononuclear cells substantially enhance antitumor activity
ConclusionSNK cells derived from peripheral blood mononuclear cells have sufficiently activated mature characteristics and high antitumor activity, rendering them a highly promising and essential therapeutic approach for cancer treatment. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Chuanling Liu, Yingying Li, Yanrong Li, Meng Hu, Haiyan Wang, Shasha Lu, Zhao Li, Dilinuer Dilimulati, Shunchang Jiao, Shelian Lu, Weihong Zhao Tags: ORIGINAL ARTICLE Source Type: research

Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity
ConclusionHuman UC-MSCs and UC-MSCs-exo improved disease characterization of SS in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Yao Zou, Wei Xiao, Dongzhou Liu, Xianyao Li, Lihua Li, Lijuan Peng, Ying Xiong, Haina Gan, Xiang Ren Tags: ORIGINAL ARTICLE Source Type: research

The role of autophagy in SIM mediated anti ‐inflammatory osteoclastogenesis through NLRP3 signaling pathway
ConclusionsSIM may reduce autophagy secretion to attenuate LPS-induced osteoclastogenesis and the NLRP3 signaling pathway participates in this process, thus providing theoretical basis for the application of this drug in peri-implantitis. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Yuting Cheng, Wenjun Jin, Lin Zheng, Xiaolin Huang, Shanshan Luo, Wei Hong, Jian Liao, Bancha Samruajbenjakun, Chidchanok Leethanakul Tags: ORIGINAL ARTICLE Source Type: research

Immune checkpoint molecules B7 ‐1 and B7‐H1 as predictive markers of pre‐eclampsia: A case–control study in a Ghana
ConclusionPE may be characterized by a dominant Th1-type immunity with higher levels of pro-inflammatory cytokines and B7-H1 proteins, but these variables may not be suitable for predicting PE. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Martin Awe Akilla, Ignatius Abowini Awinibuno Nchor, Moses Banyeh, Nafiu Amidu Tags: ORIGINAL ARTICLE Source Type: research

A community based seroprevalence of SARS ‐CoV‐2 antibodies in Somali Region, Eastern Ethiopia
ConclusionPrevalence of SARS-CoV-2 antibodies was the highest ever reported in Ethiopia, indicating that a large proportion of the population had been infected 14 months after the start of the outbreak in the country. Such studies are important to swiftly reassess and improve specific COVID-19 preventive and control measures to reduce transmissions within the community in a given setting. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 10, 2024 Category: Allergy & Immunology Authors: Solomon Yared, Tsegalem Abera, Seid Mohammed Ali, Abdifatah Muktar Muhummed, Mohammed Ibrahim, Abdullahi Hassan, Jan Hattendorf, Jakob Zinsstag, Rea Tschopp Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - January 6, 2024 Category: Allergy & Immunology Tags: ISSUE INFORMATION Source Type: research

Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review
ConclusionTherefore, it is not astonishing that dysregulations in miRNA expression patterns are now recognized in a wide spectrum of disorders, establishing themselves as potential biomarkers and therapeutic targets. Owing to its theranostic potencies, miRNA targets have been widely utilized in the development of biosensors and other therapeutic molecules originating from the same. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - December 29, 2023 Category: Allergy & Immunology Authors: Sagnik Nag, Oishi Mitra, Garima Tripathi, Souvik Samanta, Bikramjit Bhattacharya, Priti Chandane, Sourav Mohanto, Vino Sundararajan, Sumira Malik, Sarvesh Rustagi, Suraj Adhikari, Aroop Mohanty, Darwin A. Le ón‐Figueroa, Alfonso J. Rodrigu Tags: REVIEW ARTICLE Source Type: research