Forsythia suspensa (Thunb.) Vahl extract ameliorates ulcerative colitis via inhibiting NLRP3 inflammasome activation through the TLR4/MyD88/NF ‐κB pathway

ConclusionIn conclusion, PHI possesses significant anti-inflammatory properties and is expected to be a potential drug for UC treatment. Our study delves into the underlying mechanisms of PHI therapy and highlights the potential for further research in developing PHI-based treatments for UC.

Source: Immunity, Inflammation and Disease - November 7, 2023 Category: Allergy & Immunology Authors: Xiao Tong, Li Chen, Shijun He, Shuangshuang Liu, Jiaying Yao, Zhenguang Shao, Yang Ye, Sheng Yao, Zemin Lin, Jianping Zuo Tags: ORIGINAL ARTICLE Source Type: research