Shiga toxin producing Escherichia coli -associated diarrhea and hemolytic uremic syndrome in young children in Romania
ConclusionsSTEC prevalence among young children with diarrhea in Romania was high and the risk of HUS is emerging. The establishment of a systematic laboratory-based surveillance program including identification of the circulating STEC strains coupled with epidemiological investigation of HUS patients is warranted to determine the source and mode of transmission of STEC and prevent of STEC-associated diarrhea and HUS. (Source: Gut Pathogens)
Source: Gut Pathogens - September 24, 2019 Category: Microbiology Source Type: research

Genome-wide mutation analysis of Helicobacter pylori after inoculation to Mongolian gerbils
ConclusionsWe confirmed mutations in genes previously reported to be associated with adaptation to Mongolian gerbils. We also listed up genes that mutated during the infection to the gerbils, though it needs experiments to prove the influence on adaptation. (Source: Gut Pathogens)
Source: Gut Pathogens - September 20, 2019 Category: Microbiology Source Type: research

First bloodstream infection caused by Prevotella copri in a heart failure elderly patient with Prevotella -dominated gut microbiota: a case report
ConclusionsWe provide the first evidence for a clinically significant BSI caused byP. copri and its relationship to aPrevotella-rich gut microbiota in the HF patient setting. When strengthening the pathogenicity ofP. copri, the present case suggests that the gut may be a source of BSI caused by the rare anaerobic organism. Future studies are necessary to assess the role of the gut microbiota profiling for precise identification and targeted treatment of patients at high risk of BSI. (Source: Gut Pathogens)
Source: Gut Pathogens - September 17, 2019 Category: Microbiology Source Type: research

Preliminary feasibility for recruiting and retaining black and white females to provide fecal samples for longitudinal research
This article provides preliminary evidence of the feasibility of recruiting and retaining a racially diverse sample of females (97% completion for invited participants) for longitudinal microbiome research. (Source: Gut Pathogens)
Source: Gut Pathogens - August 25, 2019 Category: Microbiology Source Type: research

Differences in virulence gene expression between human blood and stool Campylobacter coli clade 1 ST828CC isolates
ConclusionsThis study reveals interesting differences betweenC. coli clade 1 isolates of human and animal origin on one hand, and also between human blood and stool isolates, on the other. The results suggest thatC. coli might downregulate and/or inactivate various virulence determinants as the isolates pass from the animal host to the human gastrointestinal tract and enter the human blood stream. (Source: Gut Pathogens)
Source: Gut Pathogens - July 31, 2019 Category: Microbiology Source Type: research