Cannabis use and cyclic vomiting syndrome
None. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 25, 2023 Category: Gastroenterology Authors: Aravind Thavamani, Senthilkumar Sankararaman Tags: Correspondence Source Type: research
A 9-year-old patient with indolent NK cell lymphoproliferative disorder: What role does an inherited SESN3 mutation play?
A 9-year-old male, who had experienced refractory hematochezia since infancy, was admitted to our hospital. He had previously gone to multiple hospitals and was successively diagnosed with eosinophilic gastroenteritis and ulcerative colitis, while the digestive ulcers did not improve after the treatment of oral glucocorticoid or infliximab. Upon admission to our hospital, all laboratory results were in the normal range, except for high platelets count and immunoglobulin E levels. Endoscopy revealed multiple ulcers throughout the digestive tract. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 23, 2023 Category: Gastroenterology Authors: Chengcheng He, Chuangzhen Lin, Mingsong Li, Yan Sun Tags: Image of the Month Source Type: research
Author's Reply: “Aquaporin 1 in cancer: Oncogene or a tumor suppressor?”
We thank the letter [1] from Guo Hongmei et al. for their attention and evaluation of our article “Aquaporin 1 is a prognostic marker and inhibits tumor progression through downregulation of Snail expression in Cholangiocarcinoma” [2]. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 23, 2023 Category: Gastroenterology Authors: Meng-Qi Zhuang, Hua-Bang Zhou, Yu-Bao Zhou Tags: Correspondence Source Type: research
A huge spleen with papillary intralymphatic angioendothelioma
A previously healthy 33-year-old woman was hospitalized with upper left quadrant mass for three months. The physical examination showed a huge mass in the upper left quadrant of abdomen. The blood tests results showed the WBC of 2.02 ×109 /L, Hb of 99 g/L and PLT of 37 × 109 /L. Enhanced abdominal computed tomography revealed a huge spleen with multiple space-occupying lesions (Fig.1A,1B). The lesions had no typical imaging features, only multiple low density lesions without obvious reinforcement were found. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 20, 2023 Category: Gastroenterology Authors: Ting Li, Jiaao Yu, Xiaodong Sun, Guoyue Lv Tags: Image of the Month Source Type: research
Tuberculous peritonitis
A 62-year-old man presented with a 2-month history of abdominal swelling, loss of appetite, and a significant 5-kilogram weight loss. Physical examination revealed emaciation, abdominal swelling, and shifting dullness. Lab tests showed monocytosis, elevated erythrocyte sedimentation rate and C-reactive protein. An 18F-fluorodeoxyglucose (18F-FDG) PET/CT scan found lung calcification, pleural effusion, mesentery, and peritoneum thickening with diffuse 18F-FDG accumulation (Fig. 1). Tuberculosis tests including anti-tuberculosis antibody test and tuberculin skin test were negative except for a slightly positive tuberculosi...
Source: Digestive and Liver Disease - November 20, 2023 Category: Gastroenterology Authors: Na Wu, Zhong Xu, Wei-Feng Huang Tags: Image of the Month Source Type: research
LncRNA AGAP2-AS1 in cancer: An insufficiently explored and controversial research area
In this study, the authors revealed that AGAP2-AS1 expression was significantly elevated in colorectal cancer (CRC) cells and could b e transcriptionally activated by E2F Transcription Factor 4 (E2F4). Down-regulated AGAP2-AS1 could weaken CRC cell growth, migration, invasion, and epithelial-mesenchymal transition (EMT). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 20, 2023 Category: Gastroenterology Authors: Hua-Wei Zhang, Li-Kai Shen Tags: Correspondence Source Type: research
Bacterial infections predispose to the development of portal vein thrombosis in patients with decompensated cirrhosis
We read with interest the original article by Dalbeni et al., investigating the association between bacterial infections and portal vein thrombosis (PVT) in cirrhosis (1). They recruited 202 consecutive patients with cirrhosis without history of bacterial infections. Patients were prospectively followed for up to 5 years or until one of the following: d eath, transplant, TIPS, PVT, or start of anticoagulation. Any episode of bacterial infection requiring hospitalization during follow-up was collected. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 20, 2023 Category: Gastroenterology Authors: Alberto Zanetto, Elena Campello, Paolo Simioni, Marco Senzolo Tags: Correspondence Source Type: research
Magnetic foreign body ingestion in pediatric age
To assess the clinical complications reported after the ingestion of magnetic foreign bodies (FBs) in pediatric age, along with their incidence among all FB ingestions and clinical presentation. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 19, 2023 Category: Gastroenterology Authors: Paolo Quitadamo, Piergiorgio Gragnaniello, Sara Isoldi, Cristina Bucci, Francesco Esposito, Silvana Russo, Maria Giovanna Grella, Mariano Caldore Tags: Alimentary Tract Source Type: research
Sieving out non-celiac gluten sensitivity amongst patients with irritable bowel syndrome
It is challenging to make diagnosis of non-celiac gluten sensitivity/non-celiac wheat sensitivity (NCGS/NCWS) in clinical practice, since there is no biomarker and diagnosis is based on response to gluten-free-diet (GFD). We used anti-gliadin antibody (AGA) for screening patients with IBS for gluten-sensitivity. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 18, 2023 Category: Gastroenterology Authors: Anam Ahmed, Kunal Dixit, Alka Singh, Ashish Agarwal, Wajiha Mehtab, Shubham Prasad, Mahendra Singh Rajput, Ashish Chauhan, Ankit Agarwal, Shubham Mehta, Vineet Ahuja, Yogesh Shouche, Dhiraj Dhotre, Govind K Makharia Tags: Alimentary Tract Source Type: research
Analysis of exposome and genetic variability suggests stress as a major contributor for development of pancreatic ductal adenocarcinoma
The current knowledge on pancreatic ductal adenocarcinoma (PDAC) risk factors is limited and no study has comprehensively tested the exposome in combination with the genetic variability in relation to the disease susceptibility. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 18, 2023 Category: Gastroenterology Authors: Giulia Peduzzi, Alessio Felici, Roberto Pellungrini, Francesca Giorgolo, Riccardo Farinella, Manuel Gentiluomo, Andrea Spinelli, Gabriele Capurso, Anna Monreale, Federico Canzian, Marco Calderisi, Daniele Campa Tags: Oncology Source Type: research
Endoscopic submucosal dissection for oesophageal cavernous haemangioma accompanied by squamous epithelial dysplasia
A 70-year-old man with dysphagia presented to our hospital. Gastroscopy revealed a submucosal eminence with a bluish surface in the anterior wall of the oesophagus 20 –23 cm from the incisor, which was soft to the touch (Fig. 1A). Endoscopic ultrasound (EUS) showed a 10.5 × 18.5 mm hypoechoic and homogeneous mass in the submucosal layer (Fig. 1B). The patient was initially diagnosed with a submucosal bulge of the oesophagus, and atypical hemangioma was t he first consideration. A subsequent computed tomography (CT) scan confirmed the presence and location of the lesion (Fig. 2). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 18, 2023 Category: Gastroenterology Authors: Chen Wu, Yuwen Pang, Xiangyu Liu, Lingyun Wang Tags: Image of the Month Source Type: research
Thiopurines have no impact on outcomes of Crohn's disease patients beyond 12 months of maintenance treatment with infliximab
The emergence of new treatments the inflammatory bowel diseases (IBD) raised questions regarding the role of older agents, namely thiopurines. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 16, 2023 Category: Gastroenterology Authors: Paula Sousa, Marta Patita, Bruno Arroja, Paula Lago, Isadora Rosa, Helena Tavares de Sousa, Paula Ministro, Irina Mocanu, Ana Vieira, Joana Castela, Joana Moleiro, Joana Roseira, Eugenia Cancela, Francisco Portela, Luis Correia, Mafalda Santiago, Sandra D Tags: Alimentary Tract Source Type: research
Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Beh çet's disease and HLA-B*46:01 for its intestinal involvement
Intestinal involvement in Beh çet's disease (BD) is associated with poor prognosis and is more prevalent in East Asian than in Mediterranean populations. Identifying the genetic causes of intestinal BD is important for understanding the pathogenesis and for appropriate treatment of BD patients. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 15, 2023 Category: Gastroenterology Authors: Eun Suk Jung, David Ellinghaus, Frauke Degenhardt, Akira Meguro, Seik-Soon Khor, S ören Mucha, Mareike Wendorff, Simonas Juzenas, Nobuhisa Mizuki, Katsushi Tokunaga, Seung Won Kim, Min Goo Lee, Stefan Schreiber, Won Ho Kim, Andre Franke, Jae Hee Cheon Tags: Alimentary Tract Source Type: research
Improve the prediction of liver transplant mortality based on pre-transplant factors: A multi-center study from China
To designed a new model using pre-transplant data to predict post-transplant mortality for Chinese population and compared its performance to that of existing models. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 14, 2023 Category: Gastroenterology Authors: Pingbo Jin, Wei Zhang, Liying Sun, Haijin Lv, Xin Duan, Yuntao Zhang, Xueli Bai, Zhijun Zhu, John Fung, Tingbo Liang Tags: Liver, Pancreas and Biliary Tract Source Type: research
Prospective evaluation of liver shearwave elastography measurements with 3 different technologies and same day liver biopsy in patients with chronic liver disease
Most ultrasound-based methods for assessing liver fibrosis still need further validation with liver biopsy used as gold standard to assess their accuracy. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - November 13, 2023 Category: Gastroenterology Authors: Sebastiana M. Atzori, Yasmin Pasha, James B. Maurice, Simon D. Taylor-Robinson, Louise Campbell, Adrian K.P. Lim Tags: Liver, Pancreas and Biliary Tract Source Type: research
