Developmental and Comparative Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Molecular characterization, cytoprotective, DNA protective, and immunological assessment of peroxiredoxin-1 (Prdx1) from yellowtail clownfish (Amphiprion clarkii)
In this study, the Prdx1 cDNA sequence was isolated from the pre-established Amphiprion clarkii (A. clarkii) (AcPrdx1) transcriptome database and characterized structurally and functionally. The AcPrdx1 coding sequence comprises 597 bp and encodes 198 amino acids with a molecular weight of 22.1 kDa and a predicted theoretical isoelectric point of 6.3. AcPrdx1 is localized and functionally available in the cytoplasm and nucleus of cells. The TXN domain of AcPrdx1 comprises two peroxiredoxin signature VCP motifs, which contain catalytic peroxidatic (Cp-C52) and resolving cysteine (CR-C173) residues. The constructed phylogene...
Source: Developmental and Comparative Immunology - April 4, 2024 Category: Allergy & Immunology Authors: D C G Rodrigo H M V Udayantha W K M Omeka D S Liyanage M A H Dilshan H A C R Hanchapola Y K Kodagoda Jihun Lee Sukkyoung Lee Taehyug Jeong Qiang Wan Jehee Lee Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

Transcriptomic profiling revealed immune-related signaling pathways in response to experimental infection of Leishmania donovani in two desert lizards from Northwest China
In this study, we conducted the first liver transcriptome analysis of two lizards (Phrynocephalus przewalskii and Eremias multiocellata) challenged with L. donovani, endemic to the steppe desert region of northwestern China. Our results revealed that multiple biological processes and immune-related signaling pathways are closely associated with the immune response to experimental L. donovani infection in the two lizards, and that both lizards show similar changes to mammals in terms of immunity to Leishmania. However, the interspecific divergence of the two lizards leads to different transcriptomic changes. In particular, ...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Yuying Xiao Jinlei He Xianguang Guo Xiaoting Zheng Zheying Zhu Qi Zhou Xuechun Liao Dali Chen Source Type: research

The expression patterns of exosomal miRNAs in the Pacific oyster after high-temperature stress or Vibrio stimulation
Dev Comp Immunol. 2024 Mar 26:105174. doi: 10.1016/j.dci.2024.105174. Online ahead of print.ABSTRACTThe exosomal miRNA plays a crucial role in the intercellular communication response to environmental stress and pathogenic stimulation. In the present study, the expression of exosomal miRNAs in the Pacific oyster Crassostrea gigas after high-temperature stress or Vibrio splendidus stimulation was characterized through high-throughput sequencing. The exosomes were identified to be teardrop-like vesicles with the average size of 81.7 nm by transmission electron microscopy. There were 66 known miRNAs and 33 novel miRNAs identi...
Source: Developmental and Comparative Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Lu Liu Lei Gao Keli Zhou Qingsong Li Hairu Xu Xingyi Feng Lingling Wang Linsheng Song Source Type: research

A trace amine associated receptor mediates antimicrobial immune response in the oyster Crassostrea gigas
Dev Comp Immunol. 2024 Mar 25:105171. doi: 10.1016/j.dci.2024.105171. Online ahead of print.ABSTRACTTrace amine-associated receptors (TAARs) are a class of G protein-coupled receptors, playing an immunomodulatory function in the neuroinflammatory responses. In the present study, a TAAR homologue with a 7tm_classA_rhodopsin-like domain (designated as CgTAAR1L) was identified in oyster Crassostrea gigas. The abundant CgTAAR1L transcripts were detected in visceral ganglia and haemocytes compared to other tissues, which were 55.35-fold and 32.95-fold (p < 0.01) of those in adductor muscle, respectively. The mRNA expression ...
Source: Developmental and Comparative Immunology - March 27, 2024 Category: Allergy & Immunology Authors: Yuehong Yang Xue Qiao Simiao Yu Xinyu Zhao Yuhao Jin Rui Liu Jie Li Lingling Wang Linsheng Song Source Type: research

The involvement of interferon regulatory factor 8 in regulating the proliferation of haemocytes in oyster Crassostrea gigas
Dev Comp Immunol. 2024 Mar 25:105172. doi: 10.1016/j.dci.2024.105172. Online ahead of print.ABSTRACTInterferon regulatory factor 8 (IRF8) is an important transcriptional regulatory factor involving in multiple biological process, such as the antiviral immune response, immune cell proliferation and differentiation. In the present study, the involvement of a previously identified IRF8 homologue (CgIRF8) in regulating haemocyte proliferation of oyster were further investigated. CgIRF8 mRNA transcripts were detectable in all the stages of C. gigas larvae with the highest level in D-veliger (1.76-fold of that in zygote, p < ...
Source: Developmental and Comparative Immunology - March 27, 2024 Category: Allergy & Immunology Authors: Zhuo Yu Xue Qiao Simiao Yu Xiaoyu Gu Yuhao Jin Chunyu Tang Jixiang Niu Lingling Wang Linsheng Song Source Type: research