Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17;150:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Functional Characterization of A Deformed Epidermal Autoregulatory Factor 1 Gene in Litopenaeus vannamei
In this study, we investigated the functions of Deformed Epidermal Autoregulatory Factor 1 (LvDEAF1) in Litopenaeus vannamei, a member of the Toll-NF-κB pathway. Our findings revealed that LvDEAF1 interacts with L. vannamei Pellino1 (LvPellino1). LvDEAF1 enhances the promoter activity of certain antimicrobial peptide genes, such as Metchnikowin and Drosomycin, in Drosophila Schneider 2 (S2) cells by binding to the NF-κB binding site. LvDEAF1 and LvPellino1 exhibit positive and synergistic effects. Additionally, the expression of LvDEAF1 is induced by Vibrio parahaemolyticus infection and lipopolysaccharides or zymosan tr...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Qian-Ming Hong Xin-Jun Yang Meng-En Zhang Qi Chen Yi-Hong Chen Source Type: research

Role of prophenoloxidase 1 from the beetle Octodonta nipae in melanized encapsulation of a wasp egg
Dev Comp Immunol. 2023 Oct 17:105082. doi: 10.1016/j.dci.2023.105082. Online ahead of print.ABSTRACTExploring the function of the host immune system can help to understand the host-parasitoid interaction. Prophenoloxidase (PPO) is crucial in defensive melanization during the encapsulation of wasp eggs. However, the existence of multiple PPO sequences increases the difficulty of exploring the specific functions of individual PPOs. We previously identified three PPOs in the nipa palm hispid beetle, Octodonta nipae. Our current work showed that OnPPO1 and OnPPO2 possessed the typical characteristics of the type III copper fam...
Source: Developmental and Comparative Immunology - October 20, 2023 Category: Allergy & Immunology Authors: Xia-Fang Zhang Wen Cui Mou-Jun Wang Yan Zhou Ting-Ting Fu Kun Jiang You-Ming Hou Bao-Zhen Tang Source Type: research

Immuno-molecular profile for Biomphalaria glabrata/Schistosoma mansoni interaction
Dev Comp Immunol. 2023 Oct 16:105083. doi: 10.1016/j.dci.2023.105083. Online ahead of print.ABSTRACTThe complex innate immune defense of Biomphalaria glabrata, the intermediate host of Schistosoma mansoni, governs the successful development of the intramolluscan stages of the parasite. The interaction between the snail and the parasite involves a complex immune molecular crosstalk between several parasite antigens and the snail immune recognition receptors, evoking different signals and effector molecules. This work seeks to discuss the immune-related molecules that influence compatibility in Biomphalaria glabrata/Schistos...
Source: Developmental and Comparative Immunology - October 18, 2023 Category: Allergy & Immunology Authors: Iman Fathy Abou-El-Naga Nermine Mogahed Fawzy Hussein Mogahed Source Type: research