Endoplasmic reticulum - condensate interactions in protein synthesis and secretion
Curr Opin Cell Biol. 2024 Apr 15;88:102357. doi: 10.1016/j.ceb.2024.102357. Online ahead of print.ABSTRACTIn the past decade, a growing amount of evidence has demonstrated that organelles do not act autonomously and independently but rather communicate with each other to coordinate different processes for proper cellular function. With a highly extended network throughout the cell, the endoplasmic reticulum (ER) plays a central role in interorganelle communication through membrane contact sites. Here, we highlight recent evidence indicating that the ER also forms contacts with membrane-less organelles. These interactions c...
Source: Current Opinion in Cell Biology - April 16, 2024 Category: Cytology Authors: Dan T M Nguyen Max Koppers Ginny G Far ías Source Type: research
Molecular cartography within axons
We describe the similarity and difference in organization of organelles and molecules in varying compartments. Finally, we highlight outstanding questions on the dynamics and localization of various components along the axon that may be answered using orthogonal approaches.PMID:38608424 | DOI:10.1016/j.ceb.2024.102358 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: A King Cada Naoko Mizuno Source Type: research
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography
Curr Opin Cell Biol. 2024 Apr 11;88:102356. doi: 10.1016/j.ceb.2024.102356. Online ahead of print.ABSTRACTCryo-electron tomography (cryo-ET) has begun to provide intricate views of cellular architecture at unprecedented resolutions. Considerable efforts are being made to further optimize and automate the cryo-ET workflow, from sample preparation to data acquisition and analysis, to enable visual proteomics inside of cells. Here, we will discuss the latest advances in cryo-ET that go hand in hand with their application to the actin cytoskeleton. The development of deep learning tools for automated annotation of tomographic ...
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: Jonathan Schneider Marion Jasnin Source Type: research
Molecular cartography within axons
We describe the similarity and difference in organization of organelles and molecules in varying compartments. Finally, we highlight outstanding questions on the dynamics and localization of various components along the axon that may be answered using orthogonal approaches.PMID:38608424 | DOI:10.1016/j.ceb.2024.102358 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: A King Cada Naoko Mizuno Source Type: research
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography
Curr Opin Cell Biol. 2024 Apr 11;88:102356. doi: 10.1016/j.ceb.2024.102356. Online ahead of print.ABSTRACTCryo-electron tomography (cryo-ET) has begun to provide intricate views of cellular architecture at unprecedented resolutions. Considerable efforts are being made to further optimize and automate the cryo-ET workflow, from sample preparation to data acquisition and analysis, to enable visual proteomics inside of cells. Here, we will discuss the latest advances in cryo-ET that go hand in hand with their application to the actin cytoskeleton. The development of deep learning tools for automated annotation of tomographic ...
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: Jonathan Schneider Marion Jasnin Source Type: research
Molecular cartography within axons
We describe the similarity and difference in organization of organelles and molecules in varying compartments. Finally, we highlight outstanding questions on the dynamics and localization of various components along the axon that may be answered using orthogonal approaches.PMID:38608424 | DOI:10.1016/j.ceb.2024.102358 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: A King Cada Naoko Mizuno Source Type: research
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography
Curr Opin Cell Biol. 2024 Apr 11;88:102356. doi: 10.1016/j.ceb.2024.102356. Online ahead of print.ABSTRACTCryo-electron tomography (cryo-ET) has begun to provide intricate views of cellular architecture at unprecedented resolutions. Considerable efforts are being made to further optimize and automate the cryo-ET workflow, from sample preparation to data acquisition and analysis, to enable visual proteomics inside of cells. Here, we will discuss the latest advances in cryo-ET that go hand in hand with their application to the actin cytoskeleton. The development of deep learning tools for automated annotation of tomographic ...
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: Jonathan Schneider Marion Jasnin Source Type: research
Molecular architecture of the actin cytoskeleton: From single cells to whole organisms using cryo-electron tomography
Curr Opin Cell Biol. 2024 Apr 11;88:102356. doi: 10.1016/j.ceb.2024.102356. Online ahead of print.ABSTRACTCryo-electron tomography (cryo-ET) has begun to provide intricate views of cellular architecture at unprecedented resolutions. Considerable efforts are being made to further optimize and automate the cryo-ET workflow, from sample preparation to data acquisition and analysis, to enable visual proteomics inside of cells. Here, we will discuss the latest advances in cryo-ET that go hand in hand with their application to the actin cytoskeleton. The development of deep learning tools for automated annotation of tomographic ...
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: Jonathan Schneider Marion Jasnin Source Type: research
Molecular cartography within axons
We describe the similarity and difference in organization of organelles and molecules in varying compartments. Finally, we highlight outstanding questions on the dynamics and localization of various components along the axon that may be answered using orthogonal approaches.PMID:38608424 | DOI:10.1016/j.ceb.2024.102358 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 12, 2024 Category: Cytology Authors: A King Cada Naoko Mizuno Source Type: research
The multidimensional roles of intermediate filaments - bridging genetic diversity with form, functions, and targets
Curr Opin Cell Biol. 2024 Apr 10;88:102354. doi: 10.1016/j.ceb.2024.102354. Online ahead of print.NO ABSTRACTPMID:38604107 | DOI:10.1016/j.ceb.2024.102354 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 11, 2024 Category: Cytology Authors: C Patrick Lusk John E Eriksson Source Type: research
The multidimensional roles of intermediate filaments - bridging genetic diversity with form, functions, and targets
Curr Opin Cell Biol. 2024 Apr 10;88:102354. doi: 10.1016/j.ceb.2024.102354. Online ahead of print.NO ABSTRACTPMID:38604107 | DOI:10.1016/j.ceb.2024.102354 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 11, 2024 Category: Cytology Authors: C Patrick Lusk John E Eriksson Source Type: research
Editorial overview: Navigating the landscapes of mechanobiology and cell-cell interactions
Curr Opin Cell Biol. 2024 Apr 3;88:102353. doi: 10.1016/j.ceb.2024.102353. Online ahead of print.NO ABSTRACTPMID:38574401 | DOI:10.1016/j.ceb.2024.102353 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 4, 2024 Category: Cytology Authors: Staffan Str ömblad Yasuyuki Fujita Source Type: research
Editorial overview: Navigating the landscapes of mechanobiology and cell-cell interactions
Curr Opin Cell Biol. 2024 Apr 3;88:102353. doi: 10.1016/j.ceb.2024.102353. Online ahead of print.NO ABSTRACTPMID:38574401 | DOI:10.1016/j.ceb.2024.102353 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 4, 2024 Category: Cytology Authors: Staffan Str ömblad Yasuyuki Fujita Source Type: research
Editorial overview: Navigating the landscapes of mechanobiology and cell-cell interactions
Curr Opin Cell Biol. 2024 Apr 3;88:102353. doi: 10.1016/j.ceb.2024.102353. Online ahead of print.NO ABSTRACTPMID:38574401 | DOI:10.1016/j.ceb.2024.102353 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 4, 2024 Category: Cytology Authors: Staffan Str ömblad Yasuyuki Fujita Source Type: research
Editorial overview: Navigating the landscapes of mechanobiology and cell-cell interactions
Curr Opin Cell Biol. 2024 Apr 3;88:102353. doi: 10.1016/j.ceb.2024.102353. Online ahead of print.NO ABSTRACTPMID:38574401 | DOI:10.1016/j.ceb.2024.102353 (Source: Current Opinion in Cell Biology)
Source: Current Opinion in Cell Biology - April 4, 2024 Category: Cytology Authors: Staffan Str ömblad Yasuyuki Fujita Source Type: research
