Intermittent Fasting Attenuates High Fat Diet-Induced Cerebellar Changes in Rats: Involvement of TNF α, autophagy and oxidative stress
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 22, 2021 Category: Cytology Source Type: research
The effectiveness of platelet-rich plasma as a carrier of stem cells in tissue regeneration: A systematic review of pre-clinical research
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 22, 2021 Category: Cytology Source Type: research
Increased expression of miR-7a-5p and miR-592 during expansion of rat dental pulp stem cells and their implication in osteogenic differentiation
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 16, 2021 Category: Cytology Source Type: research
Effect of human periodontal ligament stem cell-derived extracellular vesicles on macrophage pyroptosis and periodontal inflammatory injury in periodontitis
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 15, 2021 Category: Cytology Source Type: research
Expression and clinical significance of lncRNA OSER1-AS1 in peripheral blood of patients with non-small cell lung cancer
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 15, 2021 Category: Cytology Source Type: research
Assessment of Long-Term in vitro Multiplied Human Wharton ’s Jelly-Derived Mesenchymal Stem Cells prior to Their Use in Clinical Administration
The quantity of mesenchymal stem/stromal cells (MSCs) required for a particular therapy demands their subsequent expansion through ex vivo culture. During in vitro multiplication, they undergo replicative senescence which may alter their genetic stability. Therefore, this study was aimed to analyze cellular, molecular, and chromosomal alterations in Wharton ’s jelly-derived MSCs (WJ-MSCs) during their in vitro sequential passages, where WJ-MSCs were sequentially passaged up to P14 and cells were evaluated at an interval of P2, P6, P10, and P14. They were examined for their morphology, tumorigenicity, surface markers, ste...
Source: Cells Tissues Organs - September 14, 2021 Category: Cytology Source Type: research
Mouse Models for Human Skin Transplantation: A Systematic Review
Immunodeficient mouse models with human skin xenografts have been developed in the past decades to study different conditions of the skin. Features such as follow-up period and size of the graft are of different relevance depending on the purpose of an investigation. The aim of this study is to analyze the different mouse models grafted with human skin. A systematic review of the literature was performed in line with the PRISMA statement using MEDLINE/PubMed databases from January 1970 to June 2020. Articles describing human skin grafted onto mice were included. Animal models other than mice, skin substitutes, bioengineere...
Source: Cells Tissues Organs - September 14, 2021 Category: Cytology Source Type: research
Analgesic activity of synaptamide in a rat sciatic nerve chronic constriction injury model
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - September 10, 2021 Category: Cytology Source Type: research
A Two-Step Bioreactor for Decellularized Lung Epithelialization
Bioreactors for the reseeding of decellularized lung scaffolds have evolved with various advancements, including biomimetic mechanical stimulation, constant nutrient flow, multi-output monitoring, and large mammal scaling. Although dynamic bioreactors are not new to the field of lung bioengineering, ideal conditions during cell seeding have not been extensively studied or controlled. To address the lack of cell dispersal in traditional seeding methods, we have designed a two-step bioreactor. The first step is a novel system that rotates a seeded lung every 20 min at different angles in a sequence designed to anchor 20% of ...
Source: Cells Tissues Organs - September 9, 2021 Category: Cytology Source Type: research
Renovation of Intestinal Barrier by Polydatin in Experimentally Induced Ulcerative Colitis: Comparative Ultrastructural Study with L-Carnosine
Ulcerative colitis (UC) is a chronic inflammatory bowel disease associated with intestinal epithelial barrier impairment. Polydatin (PD), a natural product isolated fromPolygonum cuspidatum, is known to have an anti-inflammatory, antioxidant, and antiapoptotic effect. We attempted to compare the protective impact of PD pretreatment on alterations to the intestinal epithelial barrier and the colonic wall ’s ultrastructure accompanying ulcerative colitis to other conventional drugs in practice, primarily L-carnosine, which has not been addressed before. The rats were divided into 5 groups; 3 of them were treated with sulph...
Source: Cells Tissues Organs - August 30, 2021 Category: Cytology Source Type: research
Three-dimensional analysis of human laryngeal and tracheobronchial cartilages during the late embryonic and early fetal period
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - August 26, 2021 Category: Cytology Source Type: research
Synergistic Anticancer Effects of Cisplatin Combined with Combretastatin A4 Phosphate on Human Osteosarcoma-Xenografted Mice
This study aimed to investigate the effectiveness of anticancer therapy combining a cytotoxic chemotherapeutic agent, cisplatin (DDP), and a vascular disruptive drug, combretastatin A4 phosphate (CA4P), in osteosarcoma. First, a human osteosarcoma-xenografted mice model was established. Second, the transplanted tumor models were treated with DDP and CA4P in combination or as monotherapy. Third, the therapeutic effects and the mechanism of the drug combination in the inhibition of transplanted tumors was studied. Finally, the toxic effects of the drugs were observed and recorded. The results showed that DDP combined with CA...
Source: Cells Tissues Organs - August 25, 2021 Category: Cytology Source Type: research
Tubular bioartificial organs: From physiological requirements to fabrication processes and resulting properties. A critical review.
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - August 25, 2021 Category: Cytology Source Type: research
Evaluation of the postnatal effects induced by Diazinon on the Growth of the mice offspring and the development of their cerebellar cortex.
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - August 23, 2021 Category: Cytology Source Type: research
Differentiation Potential of Cultured Extracellular DEAD-Box Helicase 4+ Oogonial Stem Cells from Adult Human Ovaries into Somatic Lineages
(Source: Cells Tissues Organs)
Source: Cells Tissues Organs - August 19, 2021 Category: Cytology Source Type: research
