Decellularized Pancreas Matrix Scaffolds for Tissue Engineering Using Ductal or Arterial Catheterization
Conclusions: Using the detergent-based method, an effective and time-efficient procedure, a whole pancreas extracellular matrix bioscaffold can be developed that can be used as a 3D structure for pancreas tissue engineering-based studies and regenerative medicine applications.Cells Tissues Organs (Source: Cells Tissues Organs)
Source: Cells Tissues Organs - May 9, 2018 Category: Cytology Source Type: research
Innervation of the Human Incisive Papilla: Comparison with Other Oral Regions
Immunohistochemistry for several neurochemical substances was performed on the human incisive papilla and other oral structures. Sodium channel alpha subunit 7 (SCN7A) protein-immunoreactive (IR) Schwann cells and protein gene product 9.5 (PGP 9.5)-IR nerve fibers made nerve plexuses beneath the epithelium of the palate, including the incisive papilla, tongue, and lip. SCN7A immunoreactivity could also be detected in lamellated and nonlamellated capsules of corpuscle endings. Lamellated SCN7A-IR corpuscle endings were mostly restricted to the mucous and cutaneous lips. These endings had thick and spiral-shaped PGP 9.5-IR a...
Source: Cells Tissues Organs - May 7, 2018 Category: Cytology Source Type: research
Immunolocalization of Receptor and Chemoreceptor Modules in the Sheep Vomeronasal Organ
The vomeronasal organ (VNO) is the peripheral receptor organ of the accessory olfactory system, which is responsible for both sexual and innate behaviors. The degree of neuronal differentiation and maturation of the vomeronasal receptor cells together with the verification of the presence of the solitary chemoreceptor cells (SCCs) in the VNO of Corriedale sheep were assessed using immunofluorescence. A protein gene product 9.5 (PGP 9.5), which is a neuronal marker recognized to be expressed in most neurons of vertebrate species, an olfactory marker protein (OMP) that is precise for mature olfactory receptor cells, and last...
Source: Cells Tissues Organs - April 19, 2018 Category: Cytology Source Type: research
The Role of Epithelial < b > < i > Stat3 < /i > < /b > in Amelogenesis during Mouse Incisor Renewal
The aim of this study was to evaluate the role of epithelial signal transducer and activator of transcription 3 (STAT3) in mouse incisor amelogenesis. SinceStat3 is expressed in the epithelial component of developing and adult mouse teeth, we generated and analyzedKrt14Cre/+;Stat3fl/fl mutant mice in whichStat3 was inactivated in epithelia including ameloblast progenitors and ameloblasts, the cells responsible for enamel formation. Histological analysis showed little enamel matrix in mutant incisors compared to controls. Delayed incisor enamel mineralization was demonstrated using micro-computed X-ray tomography analysis a...
Source: Cells Tissues Organs - March 16, 2018 Category: Cytology Source Type: research
Functional Morphology of Thecal Glands in the Ovary of Japanese Quails ( < b > < i > Coturnix japonica < /i > < /b > )
The role of thecal glands in the ovary of birds remains controversial. Using transmission electron microscopy and immunohistochemistry, immunohistochemical localisation of cyclooxygenase I and II (COX-1 and COX-2), oestrogen receptor α and β (ER-α and ER-β), androgen receptor (AR) and progesterone receptor (PR), a detailed analysis of the thecal glands was performed. Our ultrastructural studies revealed that the thecal glands of the quail ovary consist of 2 cell types, steroid-producing cells (SPCs) and enclosing cells (ENCs ). The SPCs are large, light cells containing a varying number of lipid droplets. Their cytopla...
Source: Cells Tissues Organs - March 1, 2018 Category: Cytology Source Type: research
