TNF α induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes
Cytopenia is the primary feature of Myelodysplastic Syndrome, even in the presence of hypercellular bone marrow. TNF α is recognized as both a proinflammatory, and proapoptotic cytokine with a well established ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 21, 2023 Category: Cytology Authors: Anggraini Iriani, Andhika Rachman, Rahayuningsih D. Setiabudy, Siti B. Kresno, Aru W. Sudoyo, Mansyur Arief, Alida R. Harahap and Marsya Kaila Fatina Tags: Research Source Type: research
From network analysis to experimental validation: identification of regulators of non-muscle myosin II contractility using the folded-gastrulation signaling pathway
The morphogenetic process of apical constriction, which relies on non-muscle myosin II (NMII) generated constriction of apical domains of epithelial cells, is key to the development of complex cellular pattern... (Source: BMC Cell Biology)
Source: BMC Cell Biology - October 11, 2023 Category: Cytology Authors: Andy Zhao, Sophia Varady, Madelyn O ’Kelley-Bangsberg, Vicki Deng, Amy Platenkamp, Petra Wijngaard, Miriam Bern, Wyatt Gormley, Elaine Kushkowski, Kat Thompson, Logan Tibbetts, A. Tamar Conner, David Noeckel, Aidan Teran, Anna Ritz and Derek A. Applewhi Tags: Research Source Type: research
Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of cells from nasal polyps
Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to establish a robust method for the isolation and culture of epithelial cell... (Source: BMC Cell Biology)
Source: BMC Cell Biology - October 10, 2023 Category: Cytology Authors: Jonghui Kim, Karla Hegener, Claudia Hagedorn, Daniel Weidinger, Kashin Jamal Jameel, Inga Marte Charlott Seuthe, Sabine Eichhorn, Florian Kreppel, Jonas Jae-Hyun Park and J ürgen Knobloch Tags: Research Source Type: research
Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats
This study aimed to investigate the pharmacological effects and mechanisms of HRW on ionizing radiation by... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 26, 2023 Category: Cytology Authors: Xiaoming Liu, Mengya Liu, Huan Liu, Hui Yuan, Yong Wang, Xiaoman Chen, Jianguo Li and Xiujun Qin Tags: Research Source Type: research
Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities
Patients with intellectual disabilities are shown to have a limited capacity for cooperation, communication,and other biological consequences, which significantly require a specialized interest in healthcare p... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 20, 2023 Category: Cytology Authors: Ahmad H. Alghadir, Sami A. Gabr and Amir Iqbal Tags: Research Source Type: research
Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro
Inflammation plays a crucial role in the progression of Subacute Ruminal Acidosis (SARA). The experiment was designed to investigate anti-inflammatory effects of glycyrrhizin on goats ruminal epithelial cells ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 19, 2023 Category: Cytology Authors: Junfeng Liu, Bei Ma, Guang Hao, DuoDuo Su, Tianyang Wang, Ze Ding and Xuefeng Guo Tags: Research Source Type: research
D-galactose-induced mitochondrial oxidative damage and apoptosis in the cochlear stria vascularis of mice
Age-related hearing loss, known as presbycusis, is the result of auditory system degeneration. Numerous studies have suggested that reactive oxygen species (ROS) and mitochondrial oxidative damage play importa... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 21, 2023 Category: Cytology Authors: Zhe Peng, Chunli Zhao, Zijing Yang, Shusheng Gong and Zhengde Du Tags: Research Source Type: research
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA processing and long non-coding RNA localization in the nucleus. It was previously shown that shuttling of HNRNPK to the cytoplasm promotes ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 17, 2023 Category: Cytology Authors: Arwa Fallatah, Dimitrios G. Anastasakis, Amirhossein Manzourolajdad, Pooja Sharma, Xiantao Wang, Alexis Jacob, Sarah Alsharif, Ahmed Elgerbi, Pierre A. Coulombe, Markus Hafner and Byung Min Chung Tags: Research Source Type: research
A computational peptide model induces cancer cells ’ apoptosis by docking Kringle 5 to GRP78
Cells can die through a process called apoptosis in both pathological and healthy conditions. Cancer development and progression may result from abnormal apoptosis. The 78-kDa glucose-regulated protein (GRP78)... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 8, 2023 Category: Cytology Authors: Ibrahim Khater and Aaya Nassar Tags: Research Source Type: research
BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway
Bone morphogenetic protein 9 (BMP9) has been shown to regulate processes such as angiogenesis, endothelial dysfunction, and tumorigenesis. However, the role of BMP9 in preeclampsia (PE) is unclear. The purpose... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 7, 2023 Category: Cytology Authors: Xue Yang, Lingling Ren, Xiang Chen, Ying Pang, Baoxia Jia, Jing Sun and Xiaofang Quan Tags: Research Source Type: research
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance
Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood. The MAP kinase family, which plays an active... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 25, 2023 Category: Cytology Authors: Aysenur Gunaydin-Akyildiz, Rabia Sare Yanikoglu, Meltem Gulec, Gulbahar Ozge Alim-Toraman, Ebru Didem Kuran, Sezen Atasoy, Abdullah Olgun and Gulacti Topcu Tags: Research Source Type: research
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress
Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI). Dysfunction of E74-like ETS transcription factor 4 (ELF4) leads to inflammation. This research intended to look into the f... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 20, 2023 Category: Cytology Authors: Li Li, Shunying Wang and Wenming Wang Tags: Research Source Type: research
Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells
Janus kinase 3 (JAK3) is a member of the JAK family of tyrosine kinase proteins involved in cytokine receptor-mediated intracellular signal transduction through the JAK/STAT signaling pathway. JAK3 was previou... (Source: BMC Cell Biology)
Source: BMC Cell Biology - June 20, 2023 Category: Cytology Authors: Amir Zareifard, Francis Beaudry and Kalidou Ndiaye Tags: Research article Source Type: research
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2
DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both have demonstrated roles in neuronal migration, in cilia growth and function and they both are cytosk... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 26, 2023 Category: Cytology Authors: Andrea Bieder, Gayathri Chandrasekar, Arpit Wason, Steffen Erkelenz, Jay Gopalakrishnan, Juha Kere and Isabel Tapia-P áez Tags: Research article Source Type: research
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation
The platelet-derived growth factor (PDGF) family of ligands exerts their cellular effects by binding to α- and β-tyrosine kinase receptors (PDGFRα and PDGFRβ, respectively). SUMOylation is an important posttra... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 16, 2023 Category: Cytology Authors: Kehuan Wang, Natalia Papadopoulos, Anahita Hamidi, Johan Lennartsson and Carl-Henrik Heldin Tags: Research Source Type: research
