Circ-ATL1 silencing reverses the activation effects of SIRT5 on smooth muscle cellular proliferation, migration and contractility in intracranial aneurysm by adsorbing miR-455
Alterations in vascular smooth muscle cells (VSMCs) contribute to the pathogenesis of intracranial aneurysms (IAs). However, molecular mechanisms underlying these changes remain unknown. The present study aime... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 30, 2023 Category: Cytology Authors: Jichong Xu and Chun Fang Tags: Research Source Type: research
HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis
Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear. High mobility group box protein 1 (HMGB1) is associated with... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 19, 2023 Category: Cytology Authors: Jiawei Shang, Feng Zhao, Yongmei Cao, Feng Ping, Wei Wang and Yingchuan Li Tags: Research Source Type: research
N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling
Tendon injury is associated with oxidative stress, leading to reactive oxygen species (ROS) production and inflammation. N-acetyl-L-cysteine (NAC) is a potent antioxidant. However, how NAC affects the biologic... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 5, 2023 Category: Cytology Authors: Kang Lu, Mei Zhou, Liyuan Wang, Yang Wang, Hong Tang, Gang He, Huan Wang, Chuyue Tang, Jie He, Wei Wang, Kanglai Tang, Yunjiao Wang and Zhongliang Deng Tags: Research Source Type: research
The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates
Considering the high correlation between the functional decline in Alzheimer ’s disease (AD) and the propagation of aggregated tau protein, many research efforts are focused on determining the underlying molecu... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 24, 2022 Category: Cytology Authors: Andreia Ferreira, Ines Royaux, Jian Liu, Zhangjie Wang, Guowei Su, Diederik Moechars, Nico Callewaert and Louis De Muynck Tags: Research Source Type: research
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells
Inflammation is the most common cause of kidney damage, and inflammatory responses in a number of diseases are mediated by microRNA-338-3p (miR-338-3p). However, there are only a few reports which described th... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 23, 2022 Category: Cytology Authors: Jing Wang, Guokai Li, Min Lin, Sheng Lin and Ling Wu Tags: Research Source Type: research
Overexpression of lncRNA HOXA-AS2 promotes the progression of oral squamous cell carcinoma by mediating SNX5 expression
Oral squamous cell carcinoma (OSCC) is one of the most common head and neck cancers. Long non-coding RNA HOXA-AS2 (lncRNA HOXA-AS2) have been extensively studied in various cancers. However, the expression and... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 17, 2022 Category: Cytology Authors: Zhangyi Li Tags: Research Source Type: research
Overexpressed cold inducible RNA-binding protein improves cell viability and EGF expression in glial cells
Cold inducible RNA-binding protein (CIRP) is a key protein in the hypothermic therapy. Highly expressed CIRP exerts a neuroprotective effect on neurons. The aim of this study is to provide the evidence of the ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 16, 2022 Category: Cytology Authors: Aijun Liu, Shouchun Li, Yongcheng Jiao, Haibo Kong and Zhiwen Zhang Tags: Research Source Type: research
CREB1 regulates KPNA2 by inhibiting mir-495-3p transcription to control melanoma progression
Melanoma is a common type of skin cancer, and its incidence is increasing gradually. Exploring melanoma pathogenesis helps to find new treatments. (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 15, 2022 Category: Cytology Authors: Xuerui Geng, Xiujuan Qiu, Jun Gao, Zhifan Gong, Xiaogang Zhou, Chunlei Liu and Haichao Luo Tags: Research Source Type: research
Metabolic analysis of the regulatory mechanism of sugars on secondary flowering in Magnolia
Magnolia, a traditional and important ornamental plant in urban greening, has been cultivated for about 2000 years in China for its elegant flower shape and gorgeous flower color. Most varieties of Magnolia bloom... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 14, 2022 Category: Cytology Authors: Lingjuan Xuan, Qianqian Wang, Zhigao Liu, Bin Xu, Shaoyu Cheng, Yingjia Zhang, Danying Lu, Bin Dong, Dongmei Zhang, Lang Zhang, Jingjing Ma and Yamei Shen Tags: Research Source Type: research
Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeability i... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 14, 2022 Category: Cytology Authors: Fangfang Liu, Yangyang Zhang, Yining Shi, Kai Xiong, Fugui Wang and Jin Yang Tags: Research Source Type: research
Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes
Doxorubicin (DOX), which is widely used in cancer treatment, can induce cardiomyopathy. One of the main mechanisms whereby DOX induces cardiotoxicity involves pyroptosis through the NLR family pyrin domain con... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 14, 2022 Category: Cytology Authors: Soyoung Hwang, Se-Hee Kim, Kwai Han Yoo, Myung-Hee Chung, Jin Woo Lee and Kuk Hui Son Tags: Research Source Type: research
Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspikes
Placement of a cultured synovial mesenchymal stem cell (MSC) suspension on a repaired meniscus for 10 min accelerated meniscus repair. Upon placement of the MSC suspension on the meniscus, microspikes projecti... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 12, 2022 Category: Cytology Authors: Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga and Ichiro Sekiya Tags: Research article Source Type: research
RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1
Keloid is a benign proliferative fibrous disease featured by excessive fibroblast proliferation after skin injury. However, the mechanism of abnormal cell proliferation is still unclear. Herein, we investigate... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 7, 2022 Category: Cytology Authors: Hanye Liu, Guanghai Yan, Li Li, Dandan Wang, Yu Wang, Shan Jin, Zhehu Jin, Liangchang Li and Lianhua Zhu Tags: Research Source Type: research
Lncap-AI prostate cancer cell line establishment by Flutamide and androgen-free environment to promote cell adherent
To establish castration-resistant prostate cancer (CRPC) - Lncap androgen-independent (AI) cell line from Lncap androgen-dependent (AD) cell line, and explore the different molecular biological between these t... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 28, 2022 Category: Cytology Authors: Huifeng Wang, Xihua Wei, Die Zhang, Weidong Li and Yanling Hu Tags: Research Source Type: research
CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity
Ovarian cancer recurrence and chemotherapy resistance are still urgent issues, and exploring the mechanisms of metastasis and chemotherapy resistance is beneficial to the development of therapeutic methods. Ca... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 28, 2022 Category: Cytology Authors: Yanming Wang, Chao Wang and Yan Zhu Tags: Research Source Type: research
