Estrogen suppresses SOX9 and activates markers of female development in a human testis-derived cell line
The increasing incidence of reproductive disorders in humans has been attributed to in utero exposure to estrogenic endocrine disruptors. In particular, exposure of the developing testis to exogenous estrogen ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 15, 2020 Category: Cytology Authors: Melanie K. Stewart, Deidre M. Mattiske and Andrew J. Pask Tags: Research article Source Type: research
Obg-like ATPase 1 inhibited oral carcinoma cell metastasis through TGF β/SMAD2 axis in vitro
The human Obg-like ATPase 1 (OLA1) protein has been reported to play an important role in cancer cell proliferation. The molecular mechanism underlying OLA1 regulated oral metastasis is still unknown. We inves... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 14, 2020 Category: Cytology Authors: Jianzhou Liu, Qing Yang, Kevin Chen Xiao, Thomas Dobleman, Shen Hu and Gary Guishan Xiao Tags: Research article Source Type: research
Ommochrome pathway genes kynurenine 3-hydroxylase and cardinal participate in eye pigmentation in Plutella xylostella
Eye pigmentation genes have been utilized as visible markers for constructing genetic control prototypes in several insect vectors of human disease. Here, orthologs of two ommochrome pathway genes, kynurenine 3-h... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 11, 2020 Category: Cytology Authors: Xuejiao Xu, Tim Harvey-Samuel, Jie Yang, Luke Alphey and Minsheng You Tags: Research article Source Type: research
Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF
It has been demonstrated that von Willebrand factor (VWF) mediated platelet-endothelium and platelet-platelet interactions are shear dependent. The VWF ’s mobility under dynamic conditions (e.g. flow) is pivota... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 11, 2020 Category: Cytology Authors: Matthias F. Schneider, Mohammad A. Fallah, Christian Mess, Tobias Obser, Reinhard Schneppenheim, Alfredo Alexander-Katz, Stefan W. Schneider and Volker Huck Tags: Research article Source Type: research
IMPARO: inferring microbial interactions through parameter optimisation
Microbial Interaction Networks (MINs) provide important information for understanding bacterial communities. MINs can be inferred by examining microbial abundance profiles. Abundance profiles are often interpr... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 19, 2020 Category: Cytology Authors: Rajith Vidanaarachchi, Marnie Shaw, Sen-Lin Tang and Saman Halgamuge Tags: Research Source Type: research
Correction to: GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 18, 2020 Category: Cytology Authors: Oluwatosin Oluwadare, Max Highsmith, Douglass Turner, Erez Lieberman Aiden and Jianlin Cheng Tags: Correction Source Type: research
Correction to: Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 17, 2020 Category: Cytology Authors: Sandeep Singh, Varsheish Raina, Pavithra Lakshminarsimhan Chavali, Taronish Dubash, Sreenath Kadreppa, Pradeep Parab and Samit Chattopadhyay Tags: Correction Source Type: research
GSDB: a database of 3D chromosome and genome structures reconstructed from Hi-C data
Advances in the study of chromosome conformation capture technologies, such as Hi-C technique - capable of capturing chromosomal interactions in a genome-wide scale - have led to the development of three-dimen... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 5, 2020 Category: Cytology Authors: Oluwatosin Oluwadare, Max Highsmith, Douglass Turner, Erez Lieberman-Aiden and Jianlin Cheng Tags: Database Source Type: research
Exonuclease resistant 18S and 25S ribosomal RNA components in yeast are possibly newly transcribed by RNA polymerase II
We have previously reported 18S and 25S ribosomal RNA molecules in Candida albicans resistant to processive 5 ′ → 3′ exonuclease, appearing as cells approached stationary growth phase. Initial analysis pointed to ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 1, 2020 Category: Cytology Authors: Jacob Fleischmann, Miguel A. Rocha, Peter V. Hauser, Bhavani S. Gowda and Mary Grace D. Pilapil Tags: Research article Source Type: research
Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles
Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer ’s disease (AD). Recent evidence has suggested that ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 30, 2020 Category: Cytology Authors: Allaura S. Cone, Stephanie N. Hurwitz, Gloria S. Lee, Xuegang Yuan, Yi Zhou, Yan Li and David G. Meckes Jr Tags: Research article Source Type: research
An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model
This study aimed to investigate the e... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 29, 2020 Category: Cytology Authors: Jing Ai, Jian Ma, Zhi-Qing Chen, Jun-Hui Sun and Ke Yao Tags: Research article Source Type: research
Polyvalent therapeutic vaccine for type 2 diabetes mellitus: Immunoinformatics approach to study co-stimulation of cytokines and GLUT1 receptors
Type 2 diabetes mellitus (T2DM) is a worldwide disease that have an impact on individuals of all ages causing micro and macro vascular impairments due to hyperglycemic internal environment. For ultimate treatm... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 23, 2020 Category: Cytology Authors: Syed Aun Muhammad, Hiba Ashfaq, Sidra Zafar, Fahad Munir, Muhammad Babar Jamshed, Jake Chen and Qiyu Zhang Tags: Research article Source Type: research
Determinants of translation efficiency in the evolutionarily-divergent protist Trichomonas vaginalis
Trichomonas vaginalis, the causative agent of a prevalent urogenital infection in humans, is an evolutionarily divergent protozoan. Protein-coding genes in T. vaginalis are largely controlled by two core promoter... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 20, 2020 Category: Cytology Authors: Shuqi E. Wang, Anna E. S. Brooks, Anthony M. Poole and Augusto Simoes-Barbosa Tags: Research article Source Type: research
Differential contribution of p300 and CBP to regulatory element acetylation in mESCs
The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and p... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 20, 2020 Category: Cytology Authors: Sara Martire, Jennifer Nguyen, Aishwarya Sundaresan and Laura A. Banaszynski Tags: Research article Source Type: research
A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway
This study investigates the mech... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 10, 2020 Category: Cytology Authors: Yang Yang, Dan Xing, Yawei Wang, Haobo Jia, Bing Li and Jiao Jiao Li Tags: Research article Source Type: research
