Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog
Succinate dehydrogenase (Complex II) plays a dual role in respiration by catalyzing the oxidation of succinate to fumarate in the mitochondrial Krebs cycle and transferring electrons from succinate to ubiquino... (Source: BMC Cell Biology)
Source: BMC Cell Biology - June 12, 2021 Category: Cytology Authors: Aloka B. Bandara, Joshua C. Drake and David A. Brown Tags: Research article Source Type: research

Genotype-determined EGFR-RTK heterodimerization and its effects on drug resistance in lung Cancer treatment revealed by molecular dynamics simulations
Epidermal growth factor receptor (EGFR) and its signaling pathways play a vital role in pathogenesis of lung cancer. By disturbing EGFR signaling, mutations of EGFR may lead to progression of cancer or the eme... (Source: BMC Cell Biology)
Source: BMC Cell Biology - June 10, 2021 Category: Cytology Authors: Mengxu Zhu, Debby D. Wang and Hong Yan Tags: Research article Source Type: research

Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma
In the present study, fatty acid synthesis is targeted to combat mammary gland carcinoma by activating prolyl hydroxylase-2 with Voacamine alone and in combination with Tamoxifen. It was hypothesized that the ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - June 5, 2021 Category: Cytology Authors: Lakhveer Singh, Manjari Singh, Shubham Rastogi, Anurag Choudhary, Dinesh Kumar, Ritu Raj, Mohd Nazam Ansari, Abdulaziz S. Saeedan and Gaurav Kaithwas Tags: Research Source Type: research

Methodology for comprehensive cell-level analysis of wound healing experiments using deep learning in MATLAB
Endothelial healing after deployment of cardiovascular devices is particularly important in the context of clinical outcome. It is therefore of great interest to develop tools for a precise prediction of endot... (Source: BMC Cell Biology)
Source: BMC Cell Biology - June 2, 2021 Category: Cytology Authors: Jan Oldenburg, Lisa Maletzki, Anne Strohbach, Paul Bell é, Stefan Siewert, Raila Busch, Stephan B. Felix, Klaus-Peter Schmitz and Michael Stiehm Tags: Methodology article Source Type: research

Retraction Note: Evaluation of PAX8 expression promotes the proliferation of stomach Cancer cells
(Source: BMC Cell Biology)
Source: BMC Cell Biology - June 1, 2021 Category: Cytology Authors: Liang-Yu Bie, Ning Li, Wen-Ying Deng, Xiao-Yu Lu, Ping Guo and Su-Xia Luo Tags: Retraction Note Source Type: research

sFLT01 modulates invasion and metastasis in prostate cancer DU145 cells by inhibition of VEGF/GRP78/MMP2 & 9 axis
About 90% of cancer-related deaths are due to metastasis of cancer cells, and angiogenesis is a critical step in this process. sFLT01 is a novel fusion protein and a dual-targeting agent that neutralizes both ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 19, 2021 Category: Cytology Authors: Sepideh Taghizadeh, Zahra-Soheila Soheili, Mehdi Sadeghi, Shahram Samiei, Ehsan Ranaei Pirmardan, Ali Kashanian, Fahimeh Zakeri, Hamid Latifi-Navid and Hoda Shams Najafabadi Tags: Research Source Type: research

Impact of uORFs in mediating regulation of translation in stress conditions
A large fraction of genes contains upstream ORFs (uORFs) in the 5 ′ untranslated region (5’UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing prematur... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 16, 2021 Category: Cytology Authors: Simone G. Moro, Cedric Hermans, Jorge Ruiz-Orera and M. Mar Alb à Tags: Research Source Type: research

Novel leukocyte-depleted platelet-rich plasma-based skin equivalent as an in vitro model of chronic wounds: a preliminary study
Chronic leg ulcerations are associated with Haemoglobin disorders, Type2 Diabetes Mellitus, and long-term venous insufficiency, where poor perfusion and altered metabolism develop into a chronic inflammation t... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 10, 2021 Category: Cytology Authors: Elisa Seria, George Galea, Joseph Borg, Kevin Schembri, Gabriella Grech, Sarah Samut Tagliaferro and Alexander Felice Tags: Methodology article Source Type: research

Assessing nucleic acid binding activity of four dinoflagellate cold shock domain proteins from Symbiodinium kawagutii and Lingulodinium polyedra
Dinoflagellates have a generally large number of genes but only a small percentage of these are annotated as transcription factors. Cold shock domain (CSD) containing proteins (CSPs) account for roughly 60% of... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 8, 2021 Category: Cytology Authors: Bahareh Zaheri and David Morse Tags: Research Source Type: research

The Glypican proteoglycans show intrinsic interactions with Wnt-3a in human prostate cancer cells that are not always associated with cascade activation
Prostate cancer occurs through multiple steps until advanced metastasis. Signaling pathways studies can result in the identification of targets to interrupt cancer progression. Glypicans are cell surface prote... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 4, 2021 Category: Cytology Authors: Gabrielle Ferrante Alves de Moraes, Eduardo Listik, Giselle Zenker Justo, Carolina Meloni Vicente and Leny Toma Tags: Research article Source Type: research

SEM and TEM for identification of capsular fibrosis and cellular behavior around breast implants – a descriptive analysis
Capsular fibrosis (CF) is the most common long-term complication in implant-based breast augmentation. It is well accepted that the foreign body response (FBR) instigates the development of fibrotic disease. O... (Source: BMC Cell Biology)
Source: BMC Cell Biology - May 3, 2021 Category: Cytology Authors: Britta Kuehlmann, Isabel Zucal, Clark Andrew Bonham, Lydia-Marie Joubert and Lukas Prantl Tags: Methodology article Source Type: research

Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow –derived mesenchymal stem cells by regulating TP63
Progressive population aging has contributed to the increased global prevalence of diabetes and osteoporosis. Inhibition of osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by hyperglyc... (Source: BMC Cell Biology)
Source: BMC Cell Biology - April 27, 2021 Category: Cytology Authors: Fangzi Gong, Le Gao, Luyao Ma, Guangxin Li and Jianhong Yang Tags: Research Source Type: research

Online biophysical predictions for SARS-CoV-2 proteins
The SARS-CoV-2 virus, the causative agent of COVID-19, consists of an assembly of proteins that determine its infectious and immunological behavior, as well as its response to therapeutics. Major structural bi... (Source: BMC Cell Biology)
Source: BMC Cell Biology - April 23, 2021 Category: Cytology Authors: Luciano Kagami, Joel Roca-Mart ínez, Jose Gavaldá-García, Pathmanaban Ramasamy, K. Anton Feenstra and Wim F. Vranken Tags: Database Source Type: research

Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center
Sonic Hedgehog (Shh) has a catalytic cleft characteristic for zinc metallopeptidases and has significant sequence similarities with some bacterial peptidoglycan metallopeptidases defining a subgroup within the... (Source: BMC Cell Biology)
Source: BMC Cell Biology - April 16, 2021 Category: Cytology Authors: Carina J ägers and Henk Roelink Tags: Research article Source Type: research

Cyr61 promotes Schwann cell proliferation and migration via αvβ3 integrin
Schwann cells (SCs) play a crucial role in the repair of peripheral nerves. This is due to their ability to proliferate, migrate, and provide trophic support to axon regrowth. During peripheral nerve injury, S... (Source: BMC Cell Biology)
Source: BMC Cell Biology - April 7, 2021 Category: Cytology Authors: Zhenghui Cheng, Yawen Zhang, Yinchao Tian, Yuhan Chen, Fei Ding, Han Wu, Yuhua Ji and Mi Shen Tags: Research article Source Type: research

A cell-based ribozyme reporter system employing a chromosomally-integrated 5 ′ exonuclease gene
Bioinformatic genome surveys indicate that self-cleaving ribonucleic acids (ribozymes) appear to be widespread among all domains of life, although the functions of only a small number have been validated by bi... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 16, 2021 Category: Cytology Authors: Aiyada Aroonsri, Jindaporn Kongsee, Jeremy David Gunawan, Daniel Abidin Aubry and Philip James Shaw Tags: Methodology article Source Type: research

Responsiveness of human bronchial fibroblasts and epithelial cells from asthmatic and non-asthmatic donors to the transforming growth factor- β1 in epithelial-mesenchymal trophic unit model
The asthma-related airway wall remodeling is associated i.a. with a damage of bronchial epithelium and subepithelial fibrosis. Functional interactions between human bronchial epithelial cells and human bronchi... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 12, 2021 Category: Cytology Authors: Milena Paw, Dawid Wnuk, Bogdan Jakie ła, Grażyna Bochenek, Krzysztof Sładek, Zbigniew Madeja and Marta Michalik Tags: Research article Source Type: research

Intracellular pH regulation: characterization and functional investigation of H+ transporters in Stylophora pistillata
Reef-building corals regularly experience changes in intra- and extracellular H+ concentrations ([H+]) due to physiological and environmental processes. Stringent control of [H+] is required to maintain the homeo... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 8, 2021 Category: Cytology Authors: Laura Capasso, Philippe Ganot, V íctor Planas-Bielsa, Sylvie Tambutté and Didier Zoccola Tags: Research article Source Type: research

SPRD: a surface plasmon resonance database of common factors for better experimental planning
Surface plasmon resonance is a label-free biophysical technique that is widely used in investigating biomolecular interactions, including protein-protein, protein-DNA, and protein-small molecule binding. Surfa... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 6, 2021 Category: Cytology Authors: Purushottam B. Tiwari, Camelia Bencheqroun, Mario Lemus, Taryn Shaw, Marilyn Kouassi-Brou, Adil Alaoui and Aykut Üren Tags: Database Source Type: research

STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells
Staufen2 (STAU2) is an RNA binding protein involved in the posttranscriptional regulation of gene expression. In neurons, STAU2 is required to maintain the balance between differentiation and proliferation of ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 4, 2021 Category: Cytology Authors: Lionel Cond é, Yulemi Gonzalez Quesada, Florence Bonnet-Magnaval, Rémy Beaujois and Luc DesGroseillers Tags: Research article Source Type: research

Fetal sex modulates placental microRNA expression, potential microRNA-mRNA interactions, and levels of amino acid transporter expression and substrates: INFAT study subpopulation analysis of n-3 LCPUFA intervention during pregnancy and associations with offspring body composition
Previously, we revealed sexually dimorphic mRNA expression and responsiveness to maternal dietary supplementation with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in placentas from a defined INFAT stud... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 3, 2021 Category: Cytology Authors: Eva-Maria Sedlmeier, Dorothy M. Meyer, Lynne Stecher, Manuela Sailer, Hannelore Daniel, Hans Hauner and Bernhard L. Bader Tags: Research article Source Type: research

Correction to: Avian eggshell biomineralization: an update on its structure, mineralogy and protein tool kit
An amendment to this paper has been published and can be accessed via the original article. (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 22, 2021 Category: Cytology Authors: J. Gautron, L. Stapane, N. Le Roy, Y. Nys, A. B. Rodriguez-Navarro and M. T. Hincke Tags: Correction Source Type: research

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation
Human induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 18, 2021 Category: Cytology Authors: Emilia Solomon, Katie Davis-Anderson, Blake Hovde, Sofiya Micheva-Viteva, Jennifer Foster Harris, Scott Twary and Rashi Iyer Tags: Research article Source Type: research

Avian eggshell biomineralization: an update on its structure, mineralogy and protein tool kit
The avian eggshell is a natural protective envelope that relies on the phenomenon of biomineralization for its formation. The shell is made of calcium carbonate in the form of calcite, which contains hundreds ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 12, 2021 Category: Cytology Authors: J. Gautron, L. Stapane, N. Le Roy, Y. Nys, A. B. Rodriguez-Navarro and M. T. Hincke Tags: Review Source Type: research

Isolation, culture, and characterization of chicken intestinal epithelial cells
Enterocytes exert an absorptive and protective function in the intestine, and they encounter many different challenging factors such as feed, bacteria, and parasites. An intestinal epithelial in vitro model ca... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 12, 2021 Category: Cytology Authors: Federico Ghiselli, Barbara Rossi, Martina Felici, Maria Parigi, Giovanni Tosi, Laura Fiorentini, Paola Massi, Andrea Piva and Ester Grilli Tags: Methodology article Source Type: research

Increased expression of MUSASHI1 in epithelial breast cancer cells is due to down regulation of miR-125b
Musashi1 (MSI1) is an oncogenic protein with a crucial role in the proliferation and characteristics of the epithelial cells in breast cancer. The change in expression of MSI1 has a role in solid tumor progressio... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 4, 2021 Category: Cytology Authors: Mahboobeh Forouzanfar, Liana Lachinani, Kianoush Dormiani, Mohammad Hossein Nasr-Esfahani and Kamran Ghaedi Tags: Research article Source Type: research

Identification and characterization of the LRR repeats in plant LRR-RLKs
Leucine-rich-repeat receptor-like kinases (LRR-RLKs) play central roles in sensing various signals to regulate plant development and environmental responses. The extracellular domains (ECDs) of plant LRR-RLKs ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 28, 2021 Category: Cytology Authors: Tianshu Chen Tags: Research article Source Type: research

The negative charge of the 343 site is essential for maintaining physiological functions of CXCR4
Warts, hypogammaglobulinemia, recurrent bacterial infections and myelokathexis (WHIM) syndrome is a primary immunodeficiency disease (PID) usually caused by autosomal dominant mutations in the chemokine receptor (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 23, 2021 Category: Cytology Authors: Liqing Wang, Qiuhong Xiong, Ping Li, Guangxin Chen, Nayab Tariq and Changxin Wu Tags: Research article Source Type: research

Conserved paradoxical relationships among the evolutionary, structural and expressional features of KRAB zinc-finger proteins reveal their special functional characteristics
One striking feature of the large KRAB domain-containing zinc finger protein (KZFP) family is its rapid evolution, leading to hundreds of member genes with various origination time in a certain mammalian genom... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 22, 2021 Category: Cytology Authors: Pan Shen, Aishi Xu, Yushan Hou, Huqiang Wang, Chao Gao, Fuchu He and Dong Yang Tags: Research article Source Type: research

circRNA_0005529 facilitates growth and metastasis of gastric cancer via regulating miR-527/Sp1 axis
Circular RNAs (circRNAs) are endogenous non-coding RNAs, which are associated with various biological processes, including microRNA (miRNA) interaction, protein binding and regulatory splicing. circRNA_0005529... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 20, 2021 Category: Cytology Authors: Xing Zhang, Hongwei Yang, Yingdong Jia, Zhengwen Xu, Liuping Zhang, Meng Sun and Jing Fu Tags: Research article Source Type: research

NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover
Most of the cells of the mammalian retina are terminally differentiated, and do not regenerate once fully developed. This implies that these cells have strict controls over their metabolic processes, including... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 11, 2021 Category: Cytology Authors: Elisa A. Bonnin, Eugenio F. Fornasiero, Felix Lange, Christoph W. Turck and Silvio O. Rizzoli Tags: Research article Source Type: research

Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization
Human ether- à-go-go-related gene potassium channel 1 (hERG) is a voltage-gated potassium channel, the voltage-sensing domain (VSD) of which is targeted by a gating-modifier toxin, APETx1. APETx1 is a 42-residue p... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 7, 2021 Category: Cytology Authors: Kazuki Matsumura, Takushi Shimomura, Yoshihiro Kubo, Takayuki Oka, Naohiro Kobayashi, Shunsuke Imai, Naomi Yanase, Madoka Akimoto, Masahiro Fukuda, Mariko Yokogawa, Kazuyoshi Ikeda, Jun-ichi Kurita, Yoshifumi Nishimura, Ichio Shimada and Masanori Osawa Tags: Research article Source Type: research

New genotypes of Helicobacter Pylori VacA d-region identified from global strains
Pathogenesis of Helicobacter Pylori (HP) vacuolating toxin A (vacA) depends on polymorphic diversity within the signal (s), middle (m), intermediate (i), deletion (d) and c-regions. These regions show distinct al... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 7, 2021 Category: Cytology Authors: Djaleel Muhammad Soyfoo, Yussriya Hanaa Doomah, Dong Xu, Chao Zhang, Huai-Ming Sang, Yan-Yan Liu, Guo-Xin Zhang, Jian-Xia Jiang and Shun-Fu Xu Tags: Research article Source Type: research

A novel method for isolation and culture of primary swine gastric epithelial cells
Culturing primary epithelial cells has a major advantage over tumor-derived or immortalized cell lines as long as their functional phenotype and genetic makeup are mainly maintained. The swine model has shown ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 6, 2021 Category: Cytology Authors: Henry Bautista-Amorocho, Jorge Alexander Silva-Sayago, Diego A. Goyeneche-Patino, Tania Liseth P érez-Cala, Fabio Macías-Gómez, Juan Carlos Arango-Viana and Alonso Martínez Tags: Methodology article Source Type: research

Reduced translation efficiency due to novel splicing variants in 5 ′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA2
Breast cancer 2, early onset (BRCA2) is a tumor suppressor gene. The protein encoded by this gene plays an important role in homologous recombination (HR)-mediated DNA repair. Deleterious mutations in BRCA2 and d... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 6, 2021 Category: Cytology Authors: Yasunaga Yoshikawa, Hajime Kozuma, Masami Morimatsu, Kaori Sugawara and Koichi Orino Tags: Research article Source Type: research

A fast, efficient and high-throughput procedure involving laser microdissection and RT droplet digital PCR for tissue-specific expression profiling of rice roots
In rice, the cortex and outer tissues play a key role in submergence tolerance. The cortex differentiates into aerenchyma, which are air-containing cavities that allow the flow of oxygen from shoots to roots, ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 10, 2020 Category: Cytology Authors: Thibault Mounier, Sergi Navarro-Sanz, Charlotte Bureau, Lefeuvre Antoine, Fabrice Varoquaux, Franz Durandet and Christophe P érin Tags: Methodology article Source Type: research

Three functional mutation sites affect the immune response of pigs through altering the expression pattern and IgV domain of the CD4 protein
The CD4 protein is an important surface marker of T lymphocytes, which can mediate the antigen presentation process by interacting with MHC II and TCR molecules in human and mouse. (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 9, 2020 Category: Cytology Authors: Weiya Zhang, Juan Ni, Jie Zhang, Lu Zhang, Huanhuan Zhou, Changzhi Zhao, Mengjin Zhu, Haiyan Wang, Jianlin Han, Xinyun Li and Shuhong Zhao Tags: Research article Source Type: research

Regulation of the Fasciola hepatica newly excysted juvenile cathepsin L3 (FhCL3) by its propeptide: a proposed ‘clamp-like’ mechanism of binding and inhibition
The zoonotic worm parasite Fasciola hepatica secretes an abundance of cathepsin L peptidases that are associated with virulence, invasiveness, feeding and migration. The peptidases are produced as inactive zymoge... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 7, 2020 Category: Cytology Authors: Izanara C. Pritsch, Irina G. Tikhonova, Heather L. Jewhurst, Orla Drysdale, Krystyna Cwiklinski, Marcelo B. Molento, John P. Dalton and Carolina De M. Verissimo Tags: Research article Source Type: research

Designing a chimeric subunit vaccine for influenza virus, based on HA2, M2e and CTxB: a bioinformatics study
Type A influenza viruses are contagious and even life-threatening if left untreated. So far, no broadly protective vaccine is available due to rapid antigenic changes and emergence of new subtypes of influenza... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 4, 2020 Category: Cytology Authors: Davod Jafari, Sara Malih, Mohammad Mahmoudi Gomari, Marzieh Safari, Rasool Jafari and Mohammad Morad Farajollahi Tags: Research article Source Type: research

An interaction of heart disease-associated proteins POPDC1/2 with XIRP1 in transverse tubules and intercalated discs
Popeye domain-containing proteins 1 and 2 (POPDC1 and POPDC2) are transmembrane proteins involved in cyclic AMP-mediated signalling processes and are required for normal cardiac pacemaking and conduction. In o... (Source: BMC Cell Biology)
Source: BMC Cell Biology - December 1, 2020 Category: Cytology Authors: Ian Holt, Heidi R. Fuller, Roland F. R. Schindler, Sally L. Shirran, Thomas Brand and Glenn E. Morris Tags: Research article Source Type: research

Biochemical and genetic analysis of Ecm14, a conserved fungal pseudopeptidase
Like most major enzyme families, the M14 family of metallocarboxypeptidases (MCPs) contains a number of pseudoenzymes predicted to lack enzyme activity and with poorly characterized molecular function. The gen... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 30, 2020 Category: Cytology Authors: R. Christian McDonald, Matthew J. Schott, Temitope A. Idowu and Peter J. Lyons Tags: Research article Source Type: research

A novel in vitro Caenorhabditis elegans transcription system
Caenorhabditis elegans is an excellent model organism for biological research, but its contributions to biochemical elucidation of eukaryotic transcription mechanisms have been limited. One of the biggest obstacl... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 30, 2020 Category: Cytology Authors: Phillip Wibisono, Yiyong Liu and Jingru Sun Tags: Methodology article Source Type: research

Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs; liver resident macrophages) form the body ’s most effective scavenger cell system for the removal of harmful blood-borne substances, ranging fr... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 27, 2020 Category: Cytology Authors: Sabin Bhandari, Ruomei Li, Jaione Sim ón-Santamaría, Peter McCourt, Steinar Daae Johansen, Bård Smedsrød, Inigo Martinez-Zubiaurre and Karen Kristine Sørensen Tags: Research article Source Type: research

The PP1 regulator PPP1R2 coordinately regulates AURKA and PP1 to control centrosome phosphorylation and maintain central spindle architecture
Maintenance of centrosome number in cells is essential for accurate distribution of chromosomes at mitosis and is dependent on both proper centrosome duplication during interphase and their accurate distributi... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 25, 2020 Category: Cytology Authors: Alan-Michael Bresch, Nadiya Yerich, Rong Wang and Ann O. Sperry Tags: Research article Source Type: research

Regulatory effect of heat shock transcription factor-1 gene on heat shock proteins and its transcriptional regulation analysis in small abalone Haliotis diversicolor
The effects of diverse stresses ultimately alter the structures and functions of proteins. As molecular chaperones, heat shock proteins (HSPs) are a group of highly conserved proteins that help in the refoldin... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 24, 2020 Category: Cytology Authors: Xin Zhang, Yuting Li, Yulong Sun, Mingxing Guo, Jianjun Feng, Yilei Wang and Ziping Zhang Tags: Research article Source Type: research

Identification of biomarkers for the accurate and sensitive diagnosis of three bacterial pneumonia pathogens using in silico approaches
Pneumonia ranks as one of the main infectious sources of mortality among kids under 5 years of age, killing 2500 a day; late research has additionally demonstrated that mortality is higher in the elderly. A fe... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 20, 2020 Category: Cytology Authors: Olalekan Olanrewaju Bakare, Marshall Keyster and Ashley Pretorius Tags: Research article Source Type: research

Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrils
Although several studies demonstrate prion-like properties of Tau fibrils, the effect of size in the seeding capacity of these aggregates is not fully understood. The aim of this study is to characterize Tau s... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 12, 2020 Category: Cytology Authors: Andr é Marreiro, Kristof Van Kolen, Cristiano Sousa, Liesbet Temmerman, Bruno Vasconcelos, Rosa Crespo-Rodriguez, Jan R. T. van Weering, Debby Van Dam, Peter P. De Deyn, Adrian Apetri, Liliane Schoofs and Marc H. Mercken Tags: Research article Source Type: research

Egr-1 mediates low-dose arecoline induced human oral mucosa fibroblast proliferation via transactivation of Wnt5a expression
Arecoline is an alkaloid natural product found in the areca nut that can induce oral submucous fibrosis and subsequent development of cancer. However, numerous studies have shown that arecoline may inhibit fib... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 10, 2020 Category: Cytology Authors: Qiang Chen, Jiuyang Jiao, Youyuan Wang, Zhihui Mai, Jing Ren, Sijie He, Xiaolan Li and Zheng Chen Tags: Research article Source Type: research

Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation
Non-professional phagocytosis is usually triggered by stimuli such as necrotic cell death. In tumor therapy, the tumors often disappear slowly and only long time after the end of therapy. Here, tumor therapy i... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 7, 2020 Category: Cytology Authors: Dorian Gottwald, Florian Putz, Nora Hohmann, Maike B üttner-Herold, Markus Hecht, Rainer Fietkau and Luitpold Distel Tags: Research article Source Type: research

LncRNA IMFlnc1 promotes porcine intramuscular adipocyte adipogenesis by sponging miR-199a-5p to up-regulate CAV-1
Local Chinese local pig breeds have thinner muscle fiber and higher intramuscular-fat (IMF) content. But its regulation mechanism has not been discussed in-depth. Studies indicated that long non coding RNAs (l... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 4, 2020 Category: Cytology Authors: Jing Wang, Ming-yue Chen, Jun-feng Chen, Qiao-ling Ren, Jia-qing Zhang, Hai Cao, Bao-song Xing and Chuan-ying Pan Tags: Research article Source Type: research