High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients
Although hormonal and metabolic dysfunction have been recognized as a possible cause of polycystic ovarian syndrome (PCOS), the associations between hyperandrogenism and aryl hydrocarbon receptor (Ahr) signali... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 11, 2022 Category: Cytology Authors: Fatemeh Eini, Maryam Azizi kutenaei, Tahereh Foroutan and Ensieh Salehi Tags: Research Source Type: research
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression
Cholangiocarcinoma is a kind of invasive malignant tumor followed by hepatocellular carcinoma. miR-451 was suggested to function as regulator in various human tumors, but its role in mediating tumor progressio... (Source: BMC Cell Biology)
Source: BMC Cell Biology - November 9, 2022 Category: Cytology Authors: Dengfang Guo, Qingling Wang, Jiancheng Huang, Zhanglin Hu, Chun Chen, Chun Zhang and Feng Lin Tags: Research Source Type: research
Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1 β-treated chondrocyte cells
Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which it acts remains unknown. The aim of this study is to investigate the effect of acetami... (Source: BMC Cell Biology)
Source: BMC Cell Biology - October 27, 2022 Category: Cytology Authors: Jie Gao, Yan Li, Zijin Liu, Dong Wang and Huawu Zhang Tags: Research Source Type: research
CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways
Cervical cancer is an important malignant tumor threatening the physical and mental health of women in the world. As a new calcium activated chloride channel protein, calcium activated chloride channel (CLCA2) pl... (Source: BMC Cell Biology)
Source: BMC Cell Biology - October 25, 2022 Category: Cytology Authors: Wenhu Xin, Jian Zhang, Haibin Zhang, Xueyao Ma, Yunzhong Zhang, Yufeng Li and Fang Wang Tags: Research Source Type: research
The role of proteoglycan form of DMP1 in cranial repair
The cranial region is a complex set of blood vessels, cartilage, nerves and soft tissues. The reconstruction of cranial defects caused by trauma, congenital defects and surgical procedures presents clinical ch... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 30, 2022 Category: Cytology Authors: Yang Liu, Pingping Niu, Mengqi Zhou and Hui Xue Tags: Research Source Type: research
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells
COVID-19 is a disease caused by SARS-CoV-2, which can cause mild to serious infections in humans. We aimed to explore the effect of growth hormone (GH)/estrogen/androgen in normal human lung epithelial BEAS-2B... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 29, 2022 Category: Cytology Authors: Zemin Zhu, Zhijian Zhao, Xun Chen, Zhou Chu, Yi He, Yingzheng Tan, Juan Zhou and Caixi Tang Tags: Research Source Type: research
Optimization of differentiation protocols of dental tissues stem cells to pancreatic β-cells
Despite the recent progress in the differentiation strategies of stem cells into pancreatic beta cell lineage, current protocols are not optimized for different cell types. The purpose of this study is to inve... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 20, 2022 Category: Cytology Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen and Hanaa H. Ahmed Tags: Research Source Type: research
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line
Aquaporins are channel proteins, form pores in the membrane of biological cells to facilitate the transcellular and transepithelial water movement. The role of Aquaporins in carcinogenesis has become an area o... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 16, 2022 Category: Cytology Authors: Amir Hossein Mansourabadi, Azin Aghamajidi, Fatemeh Faraji, Shirin Taghizadeh, Leila Mohamed Khosroshahi, Mona Bahramkiya and Maryam Azimi Tags: Research Source Type: research
In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor
The AAA + ATPase p97 is an essential unfoldase/segragase involved in a multitude of cellular processes. It functions as a molecular machine critical for protein homeostasis, homotypic membrane fusion events an... (Source: BMC Cell Biology)
Source: BMC Cell Biology - September 10, 2022 Category: Cytology Authors: Abolfazl Mirzadeh, George Kobakhidze, R émi Vuillemot, Slavica Jonic and Isabelle Rouiller Tags: Research Source Type: research
Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics
Glioblastoma (GBM) represents nearly one-half of primary brain tumors, and the median survival of patients with GBM is only 14.6 months. Surgery followed by radiation with concomitant temozolomide (TMZ) therap... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 19, 2022 Category: Cytology Authors: Hao Chen, Chunlin Li, Haiyang Hu and Bin Zhang Tags: Research Source Type: research
Effects of an inhibitor of the SHH signaling pathway on endometrial cells of patients with endometriosis
Endometriosis is one of the most common gynecological diseases, and seriously reduces the quality of life of patients. However, the pathogenesis of this disease is unclear. Therefore, more studies are needed t... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 6, 2022 Category: Cytology Authors: Yanan He, J. Wang, Xinyan Jiang, Jianhua Gao, Yan Cheng, Tian Liang, Jun Zhou, Liyuan Sun and Guangmei Zhang Tags: Research Source Type: research
Chromatin structure in cancer
In the past decade, we have seen the emergence of sequence-based methods to understand chromosome organization. With the confluence of in situ approaches to capture information on looping, topological domains, an... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 28, 2022 Category: Cytology Authors: Meng Wang, Benjamin D. Sunkel, William C. Ray and Benjamin Z. Stanton Tags: Review Source Type: research
Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of cells. In T cells, the Nck1 isoform promotes T cell receptor signalling as well as acti... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 28, 2022 Category: Cytology Authors: Aussanee Nuiyen, Araya Rattanasri, Piyamaporn Wipa, Sittiruk Roytrakul, Apirath Wangteeraprasert, Sutatip Pongcharoen and Jutaporn Ngoenkam Tags: Research Source Type: research
lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p
Dysregulation of ACTA2-AS1 and miR-532-5p and their functions in various cancers have been widely reported. Their potential of serving as biomarkers in triple-negative breast cancer (TNBC) remains unknown. Thi... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 27, 2022 Category: Cytology Authors: Yi Peng, Xiaoxi Huang and Hongmei Wang Tags: Research Source Type: research
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing
The single-cell platform provided revolutionary way to study cellular biology. Technologically, a sophistic protocol of isolating qualified single cells would be key to deliver to single-cell platform, which r... (Source: BMC Cell Biology)
Source: BMC Cell Biology - July 26, 2022 Category: Cytology Authors: Manman Gao, Peng Guo, Xizhe Liu, Penghui Zhang, Zhongyuan He, Liru Wen, Shaoyu Liu, Zhiyu Zhou and Weimin Zhu Tags: Research article Source Type: research
