RNAP II produces capped 18S and 25S ribosomal RNAs resistant to 5 ′-monophosphate dependent processive 5′ to 3′ exonuclease in polymerase switched Saccharomyces cerevisiae
We have previously found that, in the pathogenic yeast Candida albicans, 18S and 25S ribosomal RNA components, containing more than one phosphate on their 5 ′-end were resistant to 5′-monophosphate requiring 5′ → ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - April 10, 2022 Category: Cytology Authors: Miguel A. Rocha, Bhavani S. Gowda and Jacob Fleischmann Tags: Research Source Type: research
The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids
Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential pr... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 24, 2022 Category: Cytology Authors: Ana Carolina Monteleone-Cassiano, Janaina A. Dernowsek, Romario S. Mascarenhas, Amanda Freire Assis, Dimitrius Pitol, Natalia Chermont Santos Moreira, Elza Tiemi Sakamoto-Hojo, Jo ão Paulo Mardegan Issa, Eduardo A. Donadi and Geraldo Aleixo Passos Tags: Research Source Type: research
Identification of critical residues of O-antigen-modifying O-acetyltransferase B (OacB) of Shigella flexneri
Shigellosis is an acute gastrointestinal disease caused primarily by the bacterium Shigella flexneri. Upon ingestion, S. flexneri initiates a serotype-specific immune response that targets the O-antigen of the pa... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 24, 2022 Category: Cytology Authors: Munazza I. Rajput and Naresh K. Verma Tags: Research Source Type: research
High miRNA-378 expression has high diagnostic values for pulmonary tuberculosis and predicts adverse outcomes
This study explored the effects of miR-378 on TB patients. (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 19, 2022 Category: Cytology Authors: Xiaolu Sun, Kai Liu, Yan Zhao and Tianhua Zhang Tags: Research Source Type: research
Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma
The nucleolus is a subnuclear, non-membrane bound domain that is the hub of ribosome biogenesis and a critical regulator of cell homeostasis. Rapid growth and division of cells in tumors are correlated with in... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 7, 2022 Category: Cytology Authors: Marzia Tagliaferro, Paolo Rosa, Gian Carlo Bellenchi, Daniela Bastianelli, Rosa Trotta, Claudia Tito, Francesco Fazi, Antonella Calogero and Donatella Ponti Tags: Research Source Type: research
Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody
The epidermal growth factor receptor (EGFR) is involved in various developmental processes, and alterations of its extracellular segment are associated with several types of cancers, in particular glioblastoma... (Source: BMC Cell Biology)
Source: BMC Cell Biology - March 1, 2022 Category: Cytology Authors: Matthieu R. Zeronian, Sofia Doulkeridou, Paul M. P. van Bergen en Henegouwen and Bert J. C. Janssen Tags: Research Source Type: research
Systemic administration of c-Kit+ cells diminished pulmonary and vascular inflammation in rat model of chronic asthma
To circumvent some pitfalls related to acute status, chronic model of asthma is conceived to be more suitable approach to guarantee the conditions which are similar to human pulmonary disease. Here, possible t... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 24, 2022 Category: Cytology Authors: Sajjad Taghizadeh, Rana Keyhanmanesh, Reza Rahbarghazi, Jafar Rezaie, Aref Delkhosh, Mehdi Hassanpour, Hossein Heiran, Arshad Ghaffari-Nasab and Mahdi Ahmadi Tags: Research Source Type: research
Exportin Crm1 is important for Swi6 nuclear shuttling and MBF transcription activation in Saccharomyces cerevisiae
Swi6 acts as a transcription factor in budding yeast, functioning in two different heterodimeric complexes, SBF and MBF, that activate the expression of distinct but overlapping sets of genes. Swi6 undergoes r... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 21, 2022 Category: Cytology Authors: Kenneth D. Belanger, William T. Yewdell, Matthew F. Barber, Amy N. Russo, Mark A. Pettit, Emily K. Damuth, Naveen Hussain, Susan J. Geier and Karyn G. Belanger Tags: Research Source Type: research
Optimization of fuzzy c-means (FCM) clustering in cytology image segmentation using the gray wolf algorithm
Image segmentation is considered an important step in image processing. Fuzzy c-means clustering is one of the common methods of image segmentation. However, this method suffers from drawbacks, such as sensiti... (Source: BMC Cell Biology)
Source: BMC Cell Biology - February 15, 2022 Category: Cytology Authors: Maryam Mohammdian-khoshnoud, Ali Reza Soltanian, Arash Dehghan and Maryam Farhadian Tags: Research Source Type: research
NanoBRET in C. elegans illuminates functional receptor interactions in real time
Protein-protein interactions form the basis of every organism and thus, investigating their dynamics, intracellular protein localization, trafficking and interactions of distinct proteins such as receptors and... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 31, 2022 Category: Cytology Authors: Victoria Elisabeth Gro ß, Miron Mikhailowitsch Gershkovich, Torsten Schöneberg, Anette Kaiser and Simone Prömel Tags: Research article Source Type: research
Correction to: Influence of mechanical and TGF- β3 stimulation on the tenogenic differentiation of tonsil-derived mesenchymal stem cells
(Source: BMC Cell Biology)
Source: BMC Cell Biology - January 28, 2022 Category: Cytology Authors: Jaeyeon Wee, Hyang Kim, Sang-Jin Shin, Taeyong Lee and Seung Yeol Lee Tags: Correction Source Type: research
Correction to: A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation
(Source: BMC Cell Biology)
Source: BMC Cell Biology - January 27, 2022 Category: Cytology Authors: Shannon Robin, Khalil Ben Hassine, Jayaraman Muthukumaran, Simona Jurkovic Mlakar, Maja Krajinovic, Tiago Nava, Chakradhara Rao S. Uppugunduri and Marc Ansari Tags: Correction Source Type: research
A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation
Sinusoidal occlusion syndrome (SOS) is a potentially severe complication following hematopoietic stem cell transplantation (HSCT) in pediatric patients. Treatment related risk factors such as intensity of cond... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 21, 2022 Category: Cytology Authors: Shannon Robin, Khalil Ben Hassine, Jayaraman Muthukumaran, Simona Jurkovic Mlakar, Maja Krajinovic, Tiago Nava, Chakradhara Rao S. Uppugunduri and Marc Ansari Tags: Research Source Type: research
An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin
This study aims to explore the potential underlying mechanism... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 17, 2022 Category: Cytology Authors: Xuena Yang, Xue Xiao, Lu Zhang, Bo Wang, Ping Li, Bolun Cheng, Chujun Liang, Mei Ma, Xiong Guo, Feng Zhang and Yan Wen Tags: Research Source Type: research
Influence of mechanical and TGF- β3 stimulation on the tenogenic differentiation of tonsil-derived mesenchymal stem cells
Organogenesis from tonsil-derived mesenchymal cells (TMSCs) has been reported, wherein tenogenic markers are expressed depending on the chemical stimulation during tenogenesis. However, there are insufficient ... (Source: BMC Cell Biology)
Source: BMC Cell Biology - January 15, 2022 Category: Cytology Authors: Jaeyeon Wee, Hyang Kim, Sang-Jin Shin, Taeyong Lee and Seung Yeol Lee Tags: Research article Source Type: research
